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VMAT1/SLC18A1 (SLC18A1) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1753155

Description: Rabbit IgG polyclonal antibody for VMAT1/SLC18A1 detection. Tested with WB, IHC-P, FCM, Direct ELISA in Human.Background: Chromaffin granule amine transporter is a protein that in humans is encoded by the SLC18A1 gene. This gene is mapped to… More details

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Product Overview

Online Datasheet in PDF
Product Name
VMAT1/SLC18A1, Polyclonal Antibody
Full Product Name
Anti-VMAT1/SLC18A1 Antibody
Product Gene Name
Product Synonym Names
Chromaffin granule amine transporter; Solute carrier family 18 member 1; Vesicular amine transporter 1; VAT1; SLC18A1; VAT1, VMAT1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Lyophilized
Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Purity/Purification
Immunogen affinity purified.
Specificity
No cross reactivity with other proteins.
Preparation and Storage
Store at -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen store at -20 degree C for a longer time. Avoid repeated freezing and thawing.
OMIM
193002
3D Structure
ModBase 3D Structure for P54219
Immunogen
E Coli-derived human VMAT1/SLC18A1 recombinant protein (Position: M1-E510).
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-SLC18A1 antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Flow Cytometry (FC/FACS), Direct ELISA (EIA)
Application Notes for anti-SLC18A1 antibody
WB: 0.25-0.5ug/ml (Human)
IHC-P (Embedded Section): 0.5-1ug/ml (Human)
FC/FACS: 1-3ug/1x106 cells (Human)
Direct ELISA: 0.1-0.5ug/ml (Human)
Tested Species: In-house tested species with positive results.

Flow Cytometry (FC/FACS) of anti-SLC18A1 antibody

Rabbit Anti-SLC18A1 Polyclonal Antibody – Cat# MBS1753155

Immunohistochemistry (IHC) of anti-SLC18A1 antibody

Rabbit Anti-SLC18A1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS1753155

Immunohistochemistry (IHC) of anti-SLC18A1 antibody

Rabbit Anti-SLC18A1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS1753155

Western Blot (WB) of anti-SLC18A1 antibody

Figure 1. Western blot analysis of SLC18A1 using anti-SLC18A1 antibody.
Rabbit Anti-SLC18A1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS1753155

Product References and Citations for anti-SLC18A1 antibody

1. Liu, Y., Peter, D., Roghani, A., Schuldiner, S., Prive, G. G., Eisenberg, D., Brecha, N., Edwards, R. H. A cDNA that suppresses MPP+ toxicity encodes a vesicular amine transporter. Cell 70: 539-551, 1992.
2. Peter, D., Finn, J. P., Klisak, I., Liu, Y., Kojis, T., Heinzmann, C., Roghani, A., Sparkes, R. S., Edwards, R. H. Chromosomal localization of the human vesicular amine transporter genes. Genomics 18: 720-723, 1993.
3. Roghani, A., Welch, C., Xia, Y.-R., Liu, Y., Peter, D., Finn, J. P., Edwards, R. H., Lusis, A. J. Assignment of the mouse vesicular monoamine transporter genes, Slc18a1 and Slc18a2, to chromosomes 8 and 19 by linkage analysis. Mammalian Genome 7: 393-394, 1996.

Other Notes

Small volumes of anti-SLC18A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SLC18A1 purchase

MBS1753155 is an antibody targeting SLC18A1. Also known as Anti-VMAT1/SLC18A1 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC18A1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
Chromaffin granule amine transporter
NCBI Official Synonym Full Names
solute carrier family 18 member A1
NCBI Official Symbol
SLC18A1
NCBI Official Synonym Symbols
CGAT; VAT1; VMAT1
UniProt Protein Name
Chromaffin granule amine transporter
UniProt Synonym Protein Names
Solute carrier family 18 member 1; Vesicular amine transporter 1; VAT1
UniProt Gene Name
SLC18A1
UniProt Synonym Gene Names
VAT1; VMAT1; VAT1
UniProt Entry Name
VMAT1_HUMAN
NCBI Protein Information
chromaffin granule amine transporter

NCBI Summary for SLC18A1

The vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles, using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (Peter et al., 1993 [PubMed 7905859]). See also SLC18A2 (MIM 193001).[supplied by OMIM, Mar 2008]
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UniProt Comments for SLC18A1

SLC18A1: Involved in the vesicular transport of biogenic amines. Belongs to the major facilitator superfamily. Vesicular transporter family.

Protein type: Transporter, SLC family; Membrane protein, multi-pass; Membrane protein, integral; Transporter

Chromosomal Location of Human Ortholog: 8p21.3

Cellular Component: endoplasmic reticulum membrane; integral to membrane

Molecular Function: monoamine transmembrane transporter activity; drug transporter activity

Biological Process: neurotransmitter transport; monoamine transport; multidrug transport; transmembrane transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SLC18A1 antibody

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