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RAB11B Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1753243

Description: Mouse IgG monoclonal antibody for RAB11B detection. Tested with WB,FCM in Human;Rat,Mouse.Background: Ras-related protein Rab-11B is a protein that in humans is encoded by the RAB11B gene. It is mapped to 19p13.2. The Ras superfamily of small… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RAB11B, Monoclonal Antibody
Full Product Name
Anti-RAB11B Antibody (Monoclonal, 6C5)
Product Gene Name
Product Synonym Names
Ras-related protein Rab-11B; GTP-binding protein YPT3; RAB11B; YPT3
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
6C5
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Form/Format
Lyophilized
Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Purity/Purification
Immunogen affinity purified.
Specificity
No cross reactivity with other proteins.
Preparation and Storage
Store at -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen store at -20 degree C for a longer time. Avoid repeated freezing and thawing.
OMIM
604198
3D Structure
ModBase 3D Structure for Q15907
Immunogen
A synthetic peptide corresponding to a sequence of human RAB11B (QKQIADRAAHDESPGNNVVDISVPPTTDGQKPNKLQCC).
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-RAB11B antibody
Western Blot (WB), Flow Cytometry (FC/FACS)
Application Notes for anti-RAB11B antibody
WB: 0.1-0.5ug/ml (Human, Mouse, Rat)
FC/FACS: 1-3ug/1x106 cells (Human)
Tested Species: In-house tested species with positive results.

Flow Cytometry (FC/FACS) of anti-RAB11B antibody

Mouse Anti-RAB11B Monoclonal Antibody – Cat# MBS1753243

Western Blot (WB) of anti-RAB11B antibody

Mouse Anti-RAB11B Monoclonal Antibody, Western Blot (WB) – Cat# MBS1753243

Western Blot (WB) of anti-RAB11B antibody

Mouse Anti-RAB11B Monoclonal Antibody, Western Blot (WB) – Cat# MBS1753243

Product References and Citations for anti-RAB11B antibody

1. Gross, M. B. Personal Communication. Baltimore, Md. 7/25/2014.
2. Lamers, I. J. C., Reijnders, M. R. F., Venselaar, H., Kraus, A., DDD Study, Jansen, S., de Vries, B. B. A., Houge, G., Gradek, G. A., Seo, J., Choi, M., Chae, J.-H., and 11 others. Recurrent de novo mutations disturbing the GTP/GDP binding pocket of RAB11B cause intellectual disability and a distinctive brain phenotype. Am. J. Hum. Genet. 101: 824-832, 2017.
3. Zhu, A. X., Zhao, Y., Flier, J. S. Molecular cloning of two small GTP-binding proteins from human skeletal muscle. Biochem. Biophys. Res. Commun. 205: 1875-1882, 1994.

Other Notes

Small volumes of anti-RAB11B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RAB11B purchase

MBS1753243 is an antibody targeting RAB11B. Also known as Anti-RAB11B Antibody (Monoclonal, 6C5). Reactive in Human, Mouse, Rat. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for RAB11B. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ras-related protein Rab-11B
NCBI Official Synonym Full Names
RAB11B, member RAS oncogene family
NCBI Official Symbol
RAB11B
NCBI Official Synonym Symbols
H-YPT3; NDAGSCW
UniProt Protein Name
Ras-related protein Rab-11B
UniProt Synonym Protein Names
GTP-binding protein YPT3
Protein Family
UniProt Gene Name
RAB11B
UniProt Synonym Gene Names
YPT3
UniProt Entry Name
RB11B_HUMAN
NCBI Protein Information
ras-related protein Rab-11B

NCBI Summary for RAB11B

The Ras superfamily of small GTP-binding proteins, which includes the Ras (see MIM 190020), Ral (see MIM 179550), Rho (see MIM 165390), Rap (see MIM 179520), and Rab (see MIM 179508) families, is involved in controlling a diverse set of essential cellular functions. The Rab family, including RAB11B, appears to play a critical role in regulating exocytotic and endocytotic pathways (summary by Zhu et al., 1994 [PubMed 7811277]).[supplied by OMIM, Nov 2010]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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