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IL7 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS175369

Description: Rabbit IgG polyclonal antibody for Interleukin-7(IL7) detection. Tested with WB, IHC-P in Mouse.Background: IL-7, Interleukin 7, is a protein that in humans is encoded by the IL-7 gene. IL-7 a hematopoietic growth factor secreted by stromal cells… More details

$210 / 0.01 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IL7, Polyclonal Antibody
Full Product Name
Anti-IL7 antibody
Product Gene Name
anti-IL7 antibody
Product Synonym Names
Interleukin-7(IL-7); interleukin 7; IL 7 antibody; IL-7 antibody; Il7 antibody; Interleukin 7 antibody; Interleukin-7 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Purity/Purification
Immunogen affinity purified.
Specificity
No cross reactivity with other proteins.
Preparation and Storage
Store at -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
3D Structure
ModBase 3D Structure for P10168
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of mouse IL7 (26-42aa ECHIKDKEGKAYESVLM).
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-IL7 antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin
Application Notes for anti-IL7 antibody
WB: Concentration: 0.1-0.5ug/ml; Tested Species: Mouse
IHC-P: Concentration: 0.5-1ug; Tested Species: Mouse; Antigen Retrieval: By heat

Tested Species: In house tested species with positive results.
Predicted Species: Species predicted to be fit for the product based on sequence similarities.
By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections.
Other applications have not been tested.
Optimal dilutions should be determined by end users.

Western Blot (WB) of anti-IL7 antibody

Anti-IL7 antibody, MBS175369, Western blotting
Lane 1: Recombinant Mouse IL-7 Protein 10ng
Lane 2: Recombinant Mouse IL-7 Protein 5ng
Lane 3: Recombinant Mouse IL-7 Protein 2.5ng
Rabbit Anti-IL7 Polyclonal Antibody – Cat# MBS175369

Immunohistochemistry (IHC) of anti-IL7 antibody

Anti-IL7 antibody, MBS175369, IHC(P)
IHC(P): Mouse Spleen Tissue
Rabbit Anti-IL7 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS175369

Other Notes

Small volumes of anti-IL7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL7 purchase

MBS175369 is an antibody targeting IL7. Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for IL7. It may not necessarily be applicable to this product.

NCBI GI #
124355
NCBI GeneID
16196
NCBI Accession #
P10168.1
UniProt Primary Accession #
P10168
UniProt Related Accession #
P10168
NCBI Official Full Name
Interleukin-7
NCBI Official Synonym Full Names
interleukin 7
NCBI Official Symbol
Il7
NCBI Official Synonym Symbols
Il-7; hlb368; A630026I06Rik
UniProt Protein Name
Interleukin-7
Protein Family
Interleukin
UniProt Gene Name
Il7
UniProt Synonym Gene Names
Il-7; IL-7
UniProt Entry Name
IL7_MOUSE
NCBI Protein Information
interleukin-7

NCBI Summary for IL7

The protein encoded by this gene is a hematopoietic growth factor important for B and T cell development. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]

UniProt Comments for IL7

IL7: Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell development/differentiation; Cytokine; Apoptosis; Secreted, signal peptide; Secreted; Cell cycle regulation

Cellular Component: extracellular space; extracellular region

Molecular Function: interleukin-7 receptor binding; growth factor activity; hematopoietin/interferon-class (D200-domain) cytokine receptor binding; cytokine activity

Biological Process: T cell lineage commitment; organ morphogenesis; cell-cell signaling; positive regulation of T cell differentiation; homeostasis of number of cells within a tissue; regulation of gene expression; negative regulation of catalytic activity; positive regulation of B cell proliferation; immune response; positive regulation of organ growth; humoral immune response; bone resorption
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Research Articles on IL7

1. IL-7 holds promise as a critical cytokine for selectively inducing Tfh cell generation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-IL7 antibody

 Products by Pathway  Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokines And Inflammatory Response (BioCarta) Pathway antibodies  Cytokines And Inflammatory Response (BioCarta) Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Interleukin-7 Signaling Pathway antibodies  Interleukin-7 Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram

Diseases associated with anti-IL7 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >24 publications with IL7 and Inflammation
 Necrosis Antibodies  >21 publications with IL7 and Necrosis
 Multiple Sclerosis Antibodies  >17 publications with IL7 and Multiple Sclerosis
 Lymphopenia Antibodies  >17 publications with IL7 and Lymphopenia
 Neoplasms, Experimental Antibodies  >14 publications with IL7 and Neoplasms, Experimental
 Carcinoma Antibodies  >10 publications with IL7 and Carcinoma
 Sepsis Antibodies  >6 publications with IL7 and Sepsis
 Hypersensitivity Antibodies  >6 publications with IL7 and Hypersensitivity
 Cell Transformation, Neoplastic Antibodies  >6 publications with IL7 and Cell Transformation, Neoplastic
 Neoplasm Metastasis Antibodies  >4 publications with IL7 and Neoplasm Metastasis

Organs/Tissues associated with anti-IL7 antibody

 Organ/Tissue Name  Pubmed Publications
 Thymus Antibodies  >40 publications with IL7 and Thymus
 Other Antibodies  >39 publications with IL7 and Other
 Spleen Antibodies  >12 publications with IL7 and Spleen
 Liver Antibodies  >10 publications with IL7 and Liver
 Lung Antibodies  >9 publications with IL7 and Lung
 Embryonic Tissue Antibodies  >4 publications with IL7 and Embryonic Tissue
 Ovary Antibodies  >3 publications with IL7 and Ovary
 Mammary Gland Antibodies  >2 publications with IL7 and Mammary Gland
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