TLR8 Antibody – Rabbit Polyclonal

Description: Rabbit IgG polyclonal antibody for Toll-like receptor 8(TLR8) detection. Tested with WB in Rat, Mouse.
Background: TLR8(Toll-like receptor 8) is a protein that in humans is encoded by the TLR8 gene. TLR8 has also been designated as CD288(cluster of differentiation 288). The TLR8 gene is mapped to Xp22.3-p22.2 by Chuang and Ulevitch(2000) and Du et al.(2000). The protein encoded by this gene is a member of the Toll-like receptor(TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns(PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X. TLR8 recognises G-rich oligonucleotides.

Small volumes of anti-TLR8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS175401 is an antibody targeting TLR8. Reactive in Rat
Predicted to work with: Mouse. Host: Rabbit.