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Annexin A3 (ANXA3) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS175431

Description: Rabbit IgG polyclonal antibody for Annexin A3(ANXA3) detection. Tested with WB, IHC-P in Human, Mouse, Rat.Background: Annexin A3 is a protein that in humans is encoded by the Annexin A3 gene. The Annexin A3 gene contains 13 exons and spans 58 kb… More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Annexin A3 (ANXA3), Polyclonal Antibody
Full Product Name
Anti-Annexin A3 antibody
Product Gene Name
anti-ANXA3 antibody
Product Synonym Names
Annexin A3; annexin A3; 2-cyclic phosphate 2-phosphohydrolase antibody; 35-alpha calcimedin antibody; Annexin A3 antibody; Annexin III antibody; Annexin-3 antibody; ANX3 antibody; ANXA 3 antibody; Anxa3 antibody; ANXA3_HUMAN antibody; Inositol 1 2 cyclic phosphate 2 phosphohydrolase antibody; Inositol 1 antibody; Lipocortin III antibody; OTTHUMP00000160701 antibody; OTTHUMP00000219237 antibody; OTTHUMP00000219238 antibody; PAP III antibody; PAP-III antibody; Placental anticoagulant protein III antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Lyophilized
Purity/Purification
Immunogen affinity purified.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Molecular Weight
36,363 Da
3D Structure
ModBase 3D Structure for P14669
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of rat Annexin A3 (124-141aa RQMKEISQAYYTAYKKNL), different from the related human and mouse sequences by two amino acids.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-ANXA3 antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin

Western Blot (WB) of anti-ANXA3 antibody

Anti-Annexin A3 antibody, MBS175431, Western blotting
All lanes: Anti Annexin A3 (MBS175431) at 0.5ug/ml
Lane 1: Rat Brain Tissue Lysate at 50ug
Lane 2: Rat Testis Tissue Lysate at 50ug
Lane 3: Rat Skeletal Muscle Tissue Lysate at 50ug
Lane 4: Rat Lung Tissue Lysate at 50ug
Lane 5: SW620 Whole Cell Lysate at 40ug
Lane 6: HELA Whole Cell Lysate at 40ug
Lane 7: SMMC Whole Cell Lysate at 40ug
Lane 8: MCF-7 Whole Cell Lysate at 40ug
Predicted bind size: 36KD
Observed bind size: 36KD
Rabbit Anti-ANXA3 Polyclonal Antibody – Cat# MBS175431

Immunohistochemistry (IHC) of anti-ANXA3 antibody

Anti-Annexin A3 antibody, MBS175431, IHC(P)
IHC(P): Human Mammary Cancer Tissue
Rabbit Anti-ANXA3 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS175431

Other Notes

Small volumes of anti-ANXA3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ANXA3 purchase

MBS175431 is an antibody targeting ANXA3. Also known as Anti-Annexin A3 antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ANXA3. It may not necessarily be applicable to this product.

NCBI GI #
122065130
NCBI GeneID
25291
NCBI Accession #
P14669.4
UniProt Primary Accession #
P14669
UniProt Secondary Accession #
Q642C2
UniProt Related Accession #
P14669
NCBI Official Full Name
Annexin A3
NCBI Official Synonym Full Names
annexin A3
NCBI Official Symbol
Anxa3
NCBI Official Synonym Symbols
LC3; Anx3; LRRGT00047
UniProt Protein Name
Annexin A3
UniProt Synonym Protein Names
35-alpha calcimedin; Annexin III; Annexin-3; Lipocortin III; Placental anticoagulant protein III; PAP-III
Protein Family
Annexin
UniProt Gene Name
Anxa3
UniProt Synonym Gene Names
Anx3; PAP-III
UniProt Entry Name
ANXA3_RAT
NCBI Protein Information
annexin A3; PAP-III; annexin-3; lipocortin III; 35-alpha calcimedin; Annexin III (Lipocortin III); placental anticoagulant protein III

NCBI Summary for ANXA3

inhibits phospholipase A2 activity [RGD, Feb 2006]

UniProt Comments for ANXA3

ANXA3: a calcium/phospholipid-binding protein and inhibitor of phospholipase A2, Possesses anti-coagulant properties. Cleaves the cyclic bond of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. Annexins are a family of structurally related proteins whose common property is calcium-dependent binding to phospholipids. There are at least ten different annexins in mammalian species. Annexins do not contain signal peptides, yet some annexins (A1, A2 and A5) appear to be secreted in a physiologically regulated fashion.

Protein type: Calcium-binding

Cellular Component: specific granule; phagocytic vesicle membrane; membrane; cell soma; axon; cytoplasm; dendrite; plasma membrane

Molecular Function: phospholipase inhibitor activity; calcium-dependent phospholipid binding; phospholipase A2 inhibitor activity; calcium ion binding; calcium-dependent protein binding

Biological Process: positive regulation of DNA metabolic process; organ regeneration; positive regulation of angiogenesis; hippocampus development; response to glucocorticoid stimulus; negative regulation of catalytic activity; defense response to bacterium; neutrophil degranulation; positive regulation of transcription factor activity; phagocytosis
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Research Articles on ANXA3

1. daunorubicin-induced cardiac cytotoxicity is associated with upregulation of the E3 ligases, MURF-1 and MAFbx and also caused significant increases in two markers of autophagy, beclin-1 and LC3

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ANXA3 antibody

 Reference Product  PubMed Publications
 Anxa1 antibody  >1 publications with ANXA3 and Anxa1

Pathways associated with anti-ANXA3 antibody

 Products by Pathway  Pathway Diagram
 Prostaglandin Synthesis And Regulation Pathway antibodies  Prostaglandin Synthesis And Regulation Pathway Diagram

Diseases associated with anti-ANXA3 antibody

 Disease Name  Pubmed Publications
 Prostatic Neoplasms Antibodies  >9 publications with ANXA3 and Prostatic Neoplasms
 Inflammation Antibodies  >5 publications with ANXA3 and Inflammation
 Brain Diseases Antibodies  >4 publications with ANXA3 and Brain Diseases
 Lung Neoplasms Antibodies  >4 publications with ANXA3 and Lung Neoplasms
 Carcinoma, Hepatocellular Antibodies  >3 publications with ANXA3 and Carcinoma, Hepatocellular
 Arthritis, Rheumatoid Antibodies  >3 publications with ANXA3 and Arthritis, Rheumatoid
 Pancreatic Neoplasms Antibodies  >3 publications with ANXA3 and Pancreatic Neoplasms
 Disease Models, Animal Antibodies  >3 publications with ANXA3 and Disease Models, Animal
 Liver Diseases Antibodies  >3 publications with ANXA3 and Liver Diseases
 Cardiovascular Diseases Antibodies  >3 publications with ANXA3 and Cardiovascular Diseases

Organs/Tissues associated with anti-ANXA3 antibody

 Organ/Tissue Name  Pubmed Publications
 Prostate Antibodies  >10 publications with ANXA3 and Prostate
 Liver Antibodies  >7 publications with ANXA3 and Liver
 Brain Antibodies  >5 publications with ANXA3 and Brain
 Lung Antibodies  >4 publications with ANXA3 and Lung
 Kidney Antibodies  >3 publications with ANXA3 and Kidney
 Heart Antibodies  >2 publications with ANXA3 and Heart
 Testis Antibodies  >1 publications with ANXA3 and Testis
 Placenta Antibodies  >1 publications with ANXA3 and Placenta
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