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BCAT2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS175502

Description: Rabbit IgG polyclonal antibody for Branched-chain-amino-acid aminotransferase, mitochondrial(BCAT2) detection. Tested with WB, IHC-P in Human.Background: BCAT2, branched-chain aminotransferase 2, encodes a branched chain aminotransferase found in… More details

$210 / 0.01 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
BCAT2, Polyclonal Antibody
Full Product Name
Anti-BCAT2 antibody
Product Gene Name
anti-BCAT2 antibody
Product Synonym Names
Branched-chain-amino-acid aminotransferase, mitochondrial(BCAT(m)); branched chain amino-acid transaminase 2, mitochondrial; BCAM antibody; BCAT 2 antibody; BCAT(m) antibody; BCAT2 antibody; BCAT2_HUMAN antibody; BCATM antibody; BCT2 antibody; Branched chain aminotransferase 2, mitochondrial antibody; Branched-chain-amino-acid aminotransferase antibody; ECA40 antibody; mitochondrial antibody; Placental protein 18 antibody; PP18 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Lyophilized
Purity/Purification
Immunogen affinity purified.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Molecular Weight
33,777 Da
OMIM
113530
3D Structure
ModBase 3D Structure for O15382
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human BCAT2 (377-392aa KEIQYGIRAHEWMFPV).
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-BCAT2 antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin

Western Blot (WB) of anti-BCAT2 antibody

Anti-BCAT2 antibody, MBS175502, Western blotting
All lanes: Anti BCAT2 (MBS175502) at 0.5ug/ml
Lane 1: A431 Whole Cell Lysate at 40ug
Lane 2: SW620 Whole Cell Lysate at 40ug
Lane 3: SMMC Whole Cell Lysate at 40ug
Lane 4: JURKAT Whole Cell Lysate at 40ug
Lane 5: CEM Whole Cell Lysate at 40ug
Predicted bind size: 41KD
Observed bind size: 41KD
Rabbit Anti-BCAT2 Polyclonal Antibody – Cat# MBS175502

Immunohistochemistry (IHC) of anti-BCAT2 antibody

Anti-BCAT2 antibody, MBS175502, IHC(P)
IHC(P): Human Colon Cancer Tissue
Rabbit Anti-BCAT2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS175502

Other Notes

Small volumes of anti-BCAT2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BCAT2 purchase

MBS175502 is an antibody targeting BCAT2. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for BCAT2. It may not necessarily be applicable to this product.

NCBI GI #
20455470
NCBI GeneID
587
NCBI Accession #
O15382.2
UniProt Primary Accession #
O15382
UniProt Secondary Accession #
O00269; Q96KG1; Q9BTB6; Q9BUU6; B2RB87
UniProt Related Accession #
O15382
NCBI Official Full Name
Branched-chain-amino-acid aminotransferase, mitochondrial
NCBI Official Synonym Full Names
branched chain amino-acid transaminase 2, mitochondrial
NCBI Official Symbol
BCAT2
NCBI Official Synonym Symbols
BCAM; BCT2; PP18; BCATM
UniProt Protein Name
Branched-chain-amino-acid aminotransferase, mitochondrial
UniProt Synonym Protein Names
Placental protein 18; PP18
UniProt Gene Name
BCAT2
UniProt Synonym Gene Names
BCATM; BCT2; ECA40; BCAT(m); PP18
UniProt Entry Name
BCAT2_HUMAN
NCBI Protein Information
branched-chain-amino-acid aminotransferase, mitochondrial; placental protein 18; branched chain aminotransferase 2, mitochondrial

NCBI Summary for BCAT2

This gene encodes a branched chain aminotransferase found in mitochondria. The encoded protein forms a dimer that catalyzes the first step in the production of the branched chain amino acids leucine, isoleucine, and valine. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
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UniProt Comments for BCAT2

BCAT2: Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. May also function as a transporter of branched chain alpha-keto acids. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. Homodimer. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Amino Acid Metabolism - valine, leucine and isoleucine degradation; Amino Acid Metabolism - valine, leucine and isoleucine biosynthesis; Mitochondrial; Cofactor and Vitamin Metabolism - pantothenate and CoA biosynthesis; EC 2.6.1.42; Transferase

Chromosomal Location of Human Ortholog: 19q13

Cellular Component: mitochondrion; mitochondrial matrix

Molecular Function: branched-chain-amino-acid transaminase activity

Biological Process: valine metabolic process; branched chain family amino acid catabolic process; leucine metabolic process; isoleucine catabolic process; branched chain family amino acid biosynthetic process
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Research Articles on BCAT2

1. The mitochondrial isoform human brain BCAT 2 is largely confined to vascular endothelial cells, whereas the cytosolic human brain BCAT 1 is restricted to neurons.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-BCAT2 antibody

 Reference Product  PubMed Publications
 BCKDHA antibody  >1 publications with BCAT2 and BCKDHA

Pathways associated with anti-BCAT2 antibody

 Products by Pathway  Pathway Diagram
 2-Oxocarboxylic Acid Metabolism Pathway antibodies  2-Oxocarboxylic Acid Metabolism Pathway Diagram
 2-Oxocarboxylic Acid Metabolism Pathway antibodies  2-Oxocarboxylic Acid Metabolism Pathway Diagram
 Biosynthesis Of Amino Acids Pathway antibodies  Biosynthesis Of Amino Acids Pathway Diagram
 Biosynthesis Of Amino Acids Pathway antibodies  Biosynthesis Of Amino Acids Pathway Diagram
 Branched-chain Amino Acid Catabolism Pathway antibodies  Branched-chain Amino Acid Catabolism Pathway Diagram
 Leucine Degradation, Leucine => Acetoacetate + Acetyl-CoA Pathway antibodies  Leucine Degradation, Leucine => Acetoacetate + Acetyl-CoA Pathway Diagram
 Leucine Degradation, Leucine => Acetoacetate + Acetyl-CoA Pathway antibodies  Leucine Degradation, Leucine => Acetoacetate + Acetyl-CoA Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Amino Acids And Derivatives Pathway antibodies  Metabolism Of Amino Acids And Derivatives Pathway Diagram

Diseases associated with anti-BCAT2 antibody

 Disease Name  Pubmed Publications
 Atrophy Antibodies  >1 publications with BCAT2 and Atrophy
 Adenocarcinoma Antibodies  >1 publications with BCAT2 and Adenocarcinoma
 Weight Gain Antibodies  >1 publications with BCAT2 and Weight Gain
 Weight Loss Antibodies  >1 publications with BCAT2 and Weight Loss
 Maple Syrup Urine Disease Antibodies  >1 publications with BCAT2 and Maple Syrup Urine Disease

Organs/Tissues associated with anti-BCAT2 antibody

 Organ/Tissue Name  Pubmed Publications
 Adipose Tissue Antibodies  >4 publications with BCAT2 and Adipose Tissue
 Muscle Antibodies  >4 publications with BCAT2 and Muscle
 Liver Antibodies  >2 publications with BCAT2 and Liver
 Connective Tissue Antibodies  >2 publications with BCAT2 and Connective Tissue
 Blood Antibodies  >2 publications with BCAT2 and Blood
 Brain Antibodies  >2 publications with BCAT2 and Brain
 Heart Antibodies  >1 publications with BCAT2 and Heart
 Embryonic Tissue Antibodies  >1 publications with BCAT2 and Embryonic Tissue
 Placenta Antibodies  >1 publications with BCAT2 and Placenta
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