• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

ALDH1A1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS175551

Description: Rabbit IgG polyclonal antibody for Retinal dehydrogenase 1(ALDH1A1) detection. Tested with WB, IHC-P in Human, Mouse, Rat.Background: ALDH1A1(Aldehyde dehydrogenase 1 family, member A1), also called ALDH1, RALDH1 or ALDH, LIVER CYTOSOLIC, is an… More details

$210 / 0.01 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ALDH1A1, Polyclonal Antibody
Full Product Name
Anti-ALDH1A1 antibody
Product Gene Name
anti-ALDH1A1 antibody
Product Synonym Names
Retinal dehydrogenase 1(RALDH 1/RalDH1); aldehyde dehydrogenase 1 family, member A1; Acetaldehyde dehydrogenase 1 antibody; AHD2 antibody; AL1A1_HUMAN antibody; ALDC antibody; Aldehyde dehydrogenase 1 family member A1 antibody; Aldehyde dehydrogenase 1 soluble antibody; Aldehyde dehydrogenase 1A1 antibody; Aldehyde Dehydrogenase antibody; Aldehyde dehydrogenase cytosolic antibody; Aldehyde dehydrogenase family 1 member A1 antibody; Aldehyde dehydrogenase liver cytosolic antibody; ALDH 1 antibody; ALDH 1A1 antibody; ALDH class 1 antibody; ALDH-E1 antibody; ALDH1 A1 antibody; ALDH1 antibody; ALDH11 antibody; ALDH1A1 antibody; ALHDII antibody; cytosolic antibody; MGC2318 antibody; PUMB1 antibody; RALDH 1 antibody; RalDH1 antibody; Retinal dehydrogenase 1 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Lyophilized
Purity/Purification
Immunogen affinity purified.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Molecular Weight
54,862 Da
OMIM
100640
3D Structure
ModBase 3D Structure for P00352
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human ALDH1A1 (283-303aa DLDNAVEFAHHGVFYHQGQCC), different from the related rat and mouse sequences by one amino acid.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-ALDH1A1 antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin

Western Blot (WB) of anti-ALDH1A1 antibody

Anti-ALDH1A1 antibody, MBS175551, Western blotting
Lane 1: Rat Lung Tissue Lysate
Lane 2: COLO320 Cell Lysate
Rabbit Anti-ALDH1A1 Polyclonal Antibody – Cat# MBS175551

Immunohistochemistry (IHC) of anti-ALDH1A1 antibody

Anti-ALDH1A1 antibody, MBS175551, IHC(P)
IHC(P): Human Lung Cancer Tissue
Rabbit Anti-ALDH1A1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS175551

Other Notes

Small volumes of anti-ALDH1A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ALDH1A1 purchase

MBS175551 is an antibody targeting ALDH1A1. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ALDH1A1. It may not necessarily be applicable to this product.

NCBI GI #
118495
NCBI GeneID
216
NCBI Accession #
P00352.2
UniProt Primary Accession #
P00352
UniProt Secondary Accession #
O00768; Q5SYR1
UniProt Related Accession #
P00352
NCBI Official Full Name
Retinal dehydrogenase 1
NCBI Official Synonym Full Names
aldehyde dehydrogenase 1 family, member A1
NCBI Official Symbol
ALDH1A1
NCBI Official Synonym Symbols
ALDC; ALDH1; HEL-9; HEL12; PUMB1; ALDH11; RALDH1; ALDH-E1; HEL-S-53e
UniProt Protein Name
Retinal dehydrogenase 1
UniProt Synonym Protein Names
ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase, cytosolic
Protein Family
Retinal dehydrogenase
UniProt Gene Name
ALDH1A1
UniProt Synonym Gene Names
ALDC; ALDH1; PUMB1; RALDH 1; RalDH1
UniProt Entry Name
AL1A1_HUMAN
NCBI Protein Information
retinal dehydrogenase 1; ALHDII; RALDH 1; ALDH class 1; acetaldehyde dehydrogenase 1; epididymis luminal protein 9; epididymis luminal protein 12; retinaldehyde dehydrogenase 1; aldehyde dehydrogenase 1, soluble; aldehyde dehydrogenase, liver cytosolic; epididymis secretory sperm binding protein Li 53e

NCBI Summary for ALDH1A1

The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet. [provided by RefSeq, Mar 2011]
Show more

UniProt Comments for ALDH1A1

ALDH1A1: Binds free retinal and cellular retinol-binding protein- bound retinal. Can convert/oxidize retinaldehyde to retinoic acid. Belongs to the aldehyde dehydrogenase family.

Protein type: Oxidoreductase; GAPs; Cofactor and Vitamin Metabolism - retinol; Apoptosis; GAPs, Ras; EC 1.2.1.36

Chromosomal Location of Human Ortholog: 9q21.13

Cellular Component: cytoplasm; cytosol

Molecular Function: aldehyde dehydrogenase (NAD) activity; androgen binding; 3-chloroallyl aldehyde dehydrogenase activity; benzaldehyde dehydrogenase (NAD+) activity; retinal dehydrogenase activity

Biological Process: retinol metabolic process; xenobiotic metabolic process; aldehyde metabolic process; ethanol oxidation
Show more

Research Articles on ALDH1A1

1. The increase of ALDH1A1 and GST activity in Diabetes mellitus seems to be associated with the severity of the disease and might be a compensatory effect against oxidative stress.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ALDH1A1 antibody

 Reference Product  PubMed Publications
 ADH1B antibody  >11 publications with ALDH1A1 and ADH1B
 CYP26B1 antibody  >9 publications with ALDH1A1 and CYP26B1
 CYP26A1 antibody  >7 publications with ALDH1A1 and CYP26A1
 CYP3A4 antibody  >5 publications with ALDH1A1 and CYP3A4
 ADH1A antibody  >4 publications with ALDH1A1 and ADH1A
 ADH5 antibody  >3 publications with ALDH1A1 and ADH5
 ADH7 antibody  >3 publications with ALDH1A1 and ADH7
 CYP26C1 antibody  >2 publications with ALDH1A1 and CYP26C1
 ADH6 antibody  >2 publications with ALDH1A1 and ADH6

Pathways associated with anti-ALDH1A1 antibody

 Products by Pathway  Pathway Diagram
 Biological Oxidations Pathway antibodies  Biological Oxidations Pathway Diagram
 Ethanol Oxidation Pathway antibodies  Ethanol Oxidation Pathway Diagram
 Fatty Acid Omega Oxidation Pathway antibodies  Fatty Acid Omega Oxidation Pathway Diagram
 Folate-Alcohol And Cancer Pathway antibodies  Folate-Alcohol And Cancer Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Phase 1 - Functionalization Of Compounds Pathway antibodies  Phase 1 - Functionalization Of Compounds Pathway Diagram
 Retinol Metabolism Pathway antibodies  Retinol Metabolism Pathway Diagram
 Retinol Metabolism Pathway antibodies  Retinol Metabolism Pathway Diagram
 Tryptophan Metabolism Pathway antibodies  Tryptophan Metabolism Pathway Diagram

Diseases associated with anti-ALDH1A1 antibody

 Disease Name  Pubmed Publications
 Lung Neoplasms Antibodies  >26 publications with ALDH1A1 and Lung Neoplasms
 Breast Neoplasms Antibodies  >21 publications with ALDH1A1 and Breast Neoplasms
 Disease Models, Animal Antibodies  >19 publications with ALDH1A1 and Disease Models, Animal
 Neoplasms, Experimental Antibodies  >18 publications with ALDH1A1 and Neoplasms, Experimental
 Brain Diseases Antibodies  >17 publications with ALDH1A1 and Brain Diseases
 Nervous System Diseases Antibodies  >16 publications with ALDH1A1 and Nervous System Diseases
 Liver Diseases Antibodies  >14 publications with ALDH1A1 and Liver Diseases
 Liver Neoplasms Antibodies  >12 publications with ALDH1A1 and Liver Neoplasms
 Parkinsonian Disorders Antibodies  >10 publications with ALDH1A1 and Parkinsonian Disorders
 Inflammation Antibodies  >8 publications with ALDH1A1 and Inflammation

Organs/Tissues associated with anti-ALDH1A1 antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >41 publications with ALDH1A1 and Lung
 Liver Antibodies  >38 publications with ALDH1A1 and Liver
 Blood Antibodies  >35 publications with ALDH1A1 and Blood
 Brain Antibodies  >34 publications with ALDH1A1 and Brain
 Eye Antibodies  >28 publications with ALDH1A1 and Eye
 Prostate Antibodies  >13 publications with ALDH1A1 and Prostate
 Bone Antibodies  >12 publications with ALDH1A1 and Bone
 Intestine Antibodies  >12 publications with ALDH1A1 and Intestine
 Muscle Antibodies  >11 publications with ALDH1A1 and Muscle
 Kidney Antibodies  >10 publications with ALDH1A1 and Kidney
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000