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Syntaxin 6/STX6 (STX6) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1755537

Syntaxin-6 is a protein that in humans is encoded by the STX6 gene. Enables syntaxin binding activity. Involved in several processes, including Golgi ribbon formation; retrograde transport, endosome to Golgi; and vesicle fusion. Acts upstream of or within… More details

$210 / 0.01 mg +1 FREE 8GB USB
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Testing Data View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Syntaxin 6/STX6, Polyclonal Antibody
Full Product Name
Anti-Syntaxin 6/STX6 Antibody Picoband
Product Gene Name
anti-STX6 antibody
Clonality
Polyclonal
Isotype
Rabbit IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Lyophilized
Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
Purity/Purification
Immunogen affinity purified.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. (lot specific)
Preparation and Storage
Store at -20 degree C for one year from date of receipt. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for six months.Avoid repeated freezing and thawing.
Molecular Weight
17,434 Da
OMIM
603944
3D Structure
ModBase 3D Structure for O43752
Reconstitution
Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Immunogen
E Coli-derived human Syntaxin 6/STX6 recombinant protein (Position: M1-A239).

Product Categories/Family for anti-STX6 antibody

Primary Antibodies, Rabbit Polyclonal Antibodies
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-STX6 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS), ELISA (EIA)
Application Notes for anti-STX6 antibody
WB: 0.25-0.5 ug/ml, Human, Mouse, Rat
ICC/IF: 5 ug/ml, Human
FC/FACS: 1-3 ug/1x10^6 cells, Human
Direct ELISA: 0.1-0.5 ug/ml, Human
Tested Species: In-house tested species with positive results.
Enhanced Chemiluminescent Kit with anti-Rabbit IgG (#MBS176460) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (#MBS176453) for ICC.

Other Notes

Small volumes of anti-STX6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for STX6 purchase

MBS1755537 is an antibody targeting STX6. Also known as Anti-Syntaxin 6/STX6 Antibody Picoband. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for STX6. It may not necessarily be applicable to this product.

NCBI GI #
555290010
NCBI GeneID
10228
NCBI Accession #
NP_001273139.1
UniProt Primary Accession #
O43752
UniProt Secondary Accession #
Q5VY08; Q6FH83; B2R652; B4DR17
UniProt Related Accession #
O43752
GenBank Nucleotide #
NM_001286210.1
NCBI Official Full Name
syntaxin-6 isoform 2
NCBI Official Synonym Full Names
syntaxin 6
NCBI Official Symbol
STX6
UniProt Protein Name
Syntaxin-6
Protein Family
Syntaxin
UniProt Gene Name
STX6
UniProt Entry Name
STX6_HUMAN
NCBI Protein Information
syntaxin-6

UniProt Comments for STX6

STX6: Involved in intracellular vesicle trafficking. Binds EEA1. Interacts with VPS45A. Interacts with MARCH2 and MARCH3. Interacts with GOPC. Identified in a complex containing STX6, STX12, VAMP4 and VTI1A. Belongs to the syntaxin family.

Protein type: Vesicle; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q25.3

Cellular Component: SNARE complex; Golgi membrane; Golgi apparatus; clathrin-coated vesicle; perinuclear region of cytoplasm; early endosome; plasma membrane; integral to membrane; trans-Golgi network membrane; trans-Golgi network

Molecular Function: SNAP receptor activity; protein binding; syntaxin binding

Biological Process: vesicle fusion; intracellular protein transport; regulation of protein localization; endosome organization and biogenesis; retrograde transport, endosome to Golgi; Golgi vesicle transport
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Research Articles on STX6

1. The compartment-specific interaction of Syntaxin 6 with v-SNARES VAMP3 and VAMP4 are controlled through an ability of Syntaxin 6 to sense cholesterol levels in the trans-Golgi network and recycling endosomes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-STX6 antibody

 Reference Product  PubMed Publications
 STX16 antibody  >6 publications with STX6 and STX16
 VAMP3 antibody  >4 publications with STX6 and VAMP3
 VTI1B antibody  >3 publications with STX6 and VTI1B
 VAMP4 antibody  >3 publications with STX6 and VAMP4
 VTI1A antibody  >2 publications with STX6 and VTI1A
 GOPC antibody  >2 publications with STX6 and GOPC
 VAMP8 antibody  >1 publications with STX6 and VAMP8
 MARCH2 antibody  >1 publications with STX6 and MARCH2
 SNAP23 antibody  >1 publications with STX6 and SNAP23

Pathways associated with anti-STX6 antibody

 Products by Pathway  Pathway Diagram
 SNARE Interactions In Vesicular Transport Pathway antibodies  SNARE Interactions In Vesicular Transport Pathway Diagram
 SNARE Interactions In Vesicular Transport Pathway antibodies  SNARE Interactions In Vesicular Transport Pathway Diagram

Diseases associated with anti-STX6 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >7 publications with STX6 and Nervous System Diseases
 Supranuclear Palsy, Progressive Antibodies  >5 publications with STX6 and Supranuclear Palsy, Progressive
 Nerve Degeneration Antibodies  >2 publications with STX6 and Nerve Degeneration
 Ovarian Neoplasms Antibodies  >1 publications with STX6 and Ovarian Neoplasms
 Disease Models, Animal Antibodies  >1 publications with STX6 and Disease Models, Animal
 Necrosis Antibodies  >1 publications with STX6 and Necrosis
 Inflammation Antibodies  >1 publications with STX6 and Inflammation

Organs/Tissues associated with anti-STX6 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >5 publications with STX6 and Brain
 Nerve Antibodies  >2 publications with STX6 and Nerve
 Blood Antibodies  >1 publications with STX6 and Blood
 Ovary Antibodies  >1 publications with STX6 and Ovary
 Muscle Antibodies  >1 publications with STX6 and Muscle
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