Rabbit Anti-IGFBP1 Polyclonal Antibody – Cat# MBS175710

Anti-IGFBP-1 antibody, MBS175710, Western blotting
Lane 1: SMMC Cell Lysate
Lane 2: MCF-7 Cell Lysate

IGFBP1 Antibody – Rabbit Polyclonal

Name: IGFBP1 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS175710
Price: 210 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS175710

Description: Rabbit IgG polyclonal antibody for Insulin-like growth factor-binding protein 1(IGFBP1) detection. Tested with WB in Human.Background: IGFBP1, Insulin-like growth factor-binding protein 1, also known as placental protein 12(PP12), is a protein… More details

$210 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

IGFBP1, Polyclonal Antibody

Full Product Name

Anti-IGFBP1 antibody

Product Gene Name

anti-IGFBP1 antibody

Product Synonym Names

Insulin-like growth factor-binding protein 1(IBP-1/IGF-binding protein 1/IGFBP-1); insulin-like growth factor binding protein 1; AFBP antibody; Alpha pregnancy associated endometrial globulin antibody; Amniotic fluid binding protein antibody; Binding protein 25 antibody; Binding protein 26 antibody; Binding protein 28 antibody; Growth hormone independent binding protein antibody; hIGFBP 1 antibody; hIGFBP1 antibody; IBP 1 antibody; IBP-1 antibody; IBP1 antibody; IBP1_HUMAN antibody; IGF binding protein 1 antibody; IGF BP25 antibody; IGF-binding protein 1 antibody; IGFBP 1 antibody; IGFBP-1 antibody; IGFBP1 antibody; Insulin Like Growth Factor Binding Protein 1 antibody; Insulin-like growth factor-binding protein 1 antibody; Placental protein 12 antibody; PP 12 antibody; PP12 antibody

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Lyophilized

Purity/Purification

Immunogen affinity purified.

Preparation and Storage

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

Molecular Weight

27,904 Da

OMIM

146730

3D Structure

ModBase 3D Structure for P08833

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human IGFBP1 (170-190aa KEPCRIELYRVVESLAKAQET).

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Applications Tested/Suitable for anti-IGFBP1 antibody

Western Blot (WB)

Other Notes

Small volumes of anti-IGFBP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IGFBP1 purchase

MBS175710 is an antibody targeting IGFBP1. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for IGFBP1. It may not necessarily be applicable to this product.

NCBI GI #

124055

NCBI GeneID

3484

NCBI Accession #

P08833.1

UniProt Primary Accession #

P08833

UniProt Secondary Accession #

Q8IYP5; A4D2F4; D3DVL9

UniProt Related Accession #

P08833

NCBI Official Full Name

Insulin-like growth factor-binding protein 1

NCBI Official Synonym Full Names

insulin-like growth factor binding protein 1

NCBI Official Symbol

IGFBP1

NCBI Official Synonym Symbols

AFBP; IBP1; PP12; IGF-BP25; hIGFBP-1

UniProt Protein Name

Insulin-like growth factor-binding protein 1

UniProt Synonym Protein Names

Placental protein 12; PP12

Protein Family

Insulin-like growth factor-binding protein

UniProt Gene Name

IGFBP1

UniProt Synonym Gene Names

IBP1; IBP-1; IGF-binding protein 1; IGFBP-1; PP12

UniProt Entry Name

IBP1_HUMAN

NCBI Protein Information

insulin-like growth factor-binding protein 1; IBP-1; IGFBP-1; binding protein-25; binding protein-26; binding protein-28; placental protein 12; IGF-binding protein 1; amniotic fluid binding protein; growth hormone independent-binding protein; alpha-pregnancy-associated endometrial globulin

NCBI Summary for IGFBP1

This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. [provided by RefSeq, Jul 2008]

UniProt Comments for IGFBP1

IGFBP1: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 7p12.3

Cellular Component: extracellular space; extracellular region

Molecular Function: insulin-like growth factor binding; insulin-like growth factor I binding; insulin-like growth factor II binding

Biological Process: cellular protein metabolic process; unfolded protein response, activation of signaling protein activity; regulation of insulin-like growth factor receptor signaling pathway; tissue regeneration; unfolded protein response; insulin receptor signaling pathway; signal transduction; positive regulation of cell growth

Research Articles on IGFBP1

1. DeltaIGFBP-1 as a biomarker of hepatic insulin resistance

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-IGFBP1 antibody

Reference Product	PubMed Publications
IGFBP4 antibody	>145 publications with IGFBP1 and IGFBP4
IGF1 antibody	>72 publications with IGFBP1 and IGF1
IGF2 antibody	>33 publications with IGFBP1 and IGF2
IL6 antibody	>10 publications with IGFBP1 and IL6
FOXA2 antibody	>8 publications with IGFBP1 and FOXA2
INS antibody	>6 publications with IGFBP1 and INS
ATF4 antibody	>3 publications with IGFBP1 and ATF4
HIF1A antibody	>3 publications with IGFBP1 and HIF1A
NR3C1 antibody	>1 publications with IGFBP1 and NR3C1

Pathways associated with anti-IGFBP1 antibody

Products by Pathway	Pathway Diagram
ATF4 Activates Genes Pathway antibodies	ATF4 Activates Genes Pathway Diagram
AhR Pathway antibodies	AhR Pathway Diagram
FOXA2 And FOXA3 Transcription Factor Networks Pathway antibodies	FOXA2 And FOXA3 Transcription Factor Networks Pathway Diagram
HIF-1-alpha Transcription Factor Network Pathway antibodies	HIF-1-alpha Transcription Factor Network Pathway Diagram
Metabolism Of Proteins Pathway antibodies	Metabolism Of Proteins Pathway Diagram
Myometrial Relaxation And Contraction Pathways antibodies	Myometrial Relaxation And Contraction Pathways Diagram
PERK Regulates Gene Expression Pathway antibodies	PERK Regulates Gene Expression Pathway Diagram
Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway antibodies	Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway Diagram
Unfolded Protein Response (UPR) Pathway antibodies	Unfolded Protein Response (UPR) Pathway Diagram

Diseases associated with anti-IGFBP1 antibody

Disease Name	Pubmed Publications
Liver Diseases Antibodies	>129 publications with IGFBP1 and Liver Diseases
Cardiovascular Diseases Antibodies	>122 publications with IGFBP1 and Cardiovascular Diseases
Disease Models, Animal Antibodies	>90 publications with IGFBP1 and Disease Models, Animal
Kidney Diseases Antibodies	>83 publications with IGFBP1 and Kidney Diseases
Liver Neoplasms Antibodies	>81 publications with IGFBP1 and Liver Neoplasms
Adenocarcinoma Antibodies	>80 publications with IGFBP1 and Adenocarcinoma
Brain Diseases Antibodies	>75 publications with IGFBP1 and Brain Diseases
Necrosis Antibodies	>65 publications with IGFBP1 and Necrosis
Inflammation Antibodies	>62 publications with IGFBP1 and Inflammation
Hyperglycemia Antibodies	>56 publications with IGFBP1 and Hyperglycemia

Organs/Tissues associated with anti-IGFBP1 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>1319 publications with IGFBP1 and Blood
Liver Antibodies	>449 publications with IGFBP1 and Liver
Uterus Antibodies	>326 publications with IGFBP1 and Uterus
Placenta Antibodies	>238 publications with IGFBP1 and Placenta
Embryonic Tissue Antibodies	>130 publications with IGFBP1 and Embryonic Tissue
Bone Antibodies	>97 publications with IGFBP1 and Bone
Brain Antibodies	>85 publications with IGFBP1 and Brain
Lung Antibodies	>46 publications with IGFBP1 and Lung
Pancreas Antibodies	>31 publications with IGFBP1 and Pancreas
Skin Antibodies	>31 publications with IGFBP1 and Skin