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P2RX6 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS176031

Description: Rabbit IgG polyclonal antibody for P2X purinoceptor 6(P2RX6) detection. Tested with WB in Human.Background: Purinergic receptor P2X-Like 1, also known as P2X6, is a protein that in humans is encoded by the P2RX6 gene. The encoded protein is… More details

$210 / 0.01 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
P2X6 (P2RX6), Polyclonal Antibody
Full Product Name
Anti-P2X6 antibody
Product Gene Name
Product Synonym Names
P2X purinoceptor 6; purinergic receptor P2X, ligand-gated ion channel, 6; ATP receptor antibody; P2RX6 antibody; P2RX6_HUMAN antibody; P2RXL1 antibody; P2X purinoceptor 6 antibody; P2X6 antibody; P2XM antibody; Purinergic receptor antibody; Purinergic receptor P2X ligand gated ion channel 6 antibody; Purinergic receptor P2X like 1 antibody; Purinergic receptor P2X-like 1 antibody; Purinoceptor P2X6 antibody; Purinoreceptor P2X6 antibody; Skeletal muscle expressed P2X antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Lyophilized
Purity/Purification
Immunogen affinity purified.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Molecular Weight
45,808 Da
OMIM
608077
3D Structure
ModBase 3D Structure for O15547
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human P2X6 (387-406aa VWRELALASQARLAECLRRS).
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-P2RX6 antibody
Western Blot (WB)

Western Blot (WB) of anti-P2RX6 antibody

Anti-P2X6 antibody, MBS176031, Western blotting
Lane 1: U87 Cell Lysate
Lane 2: 22RV1 Cell Lysate
Lane 3: JURKAT Cell Lysate
Lane 4: HT1080 Cell Lysate
Rabbit Anti-P2RX6 Polyclonal Antibody – Cat# MBS176031

Other Notes

Small volumes of anti-P2RX6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for P2RX6 purchase

MBS176031 is an antibody targeting P2RX6. Also known as Anti-P2X6 antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for P2RX6. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
P2X purinoceptor 6
NCBI Official Synonym Full Names
purinergic receptor P2X, ligand-gated ion channel, 6
NCBI Official Symbol
P2RX6
NCBI Official Synonym Symbols
P2X6; P2XM; P2RXL1
UniProt Protein Name
P2X purinoceptor 6
UniProt Synonym Protein Names
ATP receptor; P2XM; Purinergic receptor; Purinergic receptor P2X-like 1
Protein Family
UniProt Gene Name
P2RX6
UniProt Synonym Gene Names
P2RXL1; P2X6; P2X6
UniProt Entry Name
P2RX6_HUMAN
NCBI Protein Information
P2X purinoceptor 6; ATP receptor; purinoceptor P2X6; purinoreceptor P2X6; skeletal muscle-expressed P2X; purinergic receptor P2X-like 1, orphan receptor

NCBI Summary for P2RX6

The protein encoded by this gene belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. This gene is predominantly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 22, has been identified. [provided by RefSeq, Apr 2009]
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UniProt Comments for P2RX6

P2X6: Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Channel, cation; Receptor, misc.; Channel, ligand-gated

Chromosomal Location of Human Ortholog: 22q11.21

Cellular Component: cell soma; integral to plasma membrane; postsynaptic density; cytoplasm; dendritic spine; integral to nuclear inner membrane; cell junction

Molecular Function: identical protein binding; transmembrane receptor activity; channel activity; purinergic nucleotide receptor activity; ATP binding; ATP-gated cation channel activity

Biological Process: muscle contraction; transport; protein heterooligomerization; signal transduction; transmembrane transport; protein homooligomerization; cation transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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