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Aquaporin 0 (MIP) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS176068

Description: Rabbit IgG polyclonal antibody for Lens fiber major intrinsic protein(MIP) detection. Tested with WB in Human, Mouse, Rat.Background: Lens fiber major intrinsic protein also called MIP26 or MP26 is a protein that in humans is encoded by the MIP… More details

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Product Overview

Online Datasheet in PDF
Product Name
Aquaporin 0 (MIP), Polyclonal Antibody
Full Product Name
Anti-Aquaporin 0 antibody
Product Gene Name
Product Synonym Names
Lens fiber major intrinsic protein; major intrinsic protein of lens fiber; AQP 0 antibody; AQP0 antibody; Aquaporin antibody; Aquaporin0 antibody; Lens fiber major intrinsic protein antibody; LIM 1 antibody; LIM1 antibody; Major intrinsic protein 26kD antibody; Major intrinsic protein of lens fiber antibody; MIP 26 antibody; MIP antibody; MIP26 antibody; MP 26 antibody; MP26 antibody; PALM antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Lyophilized
Purity/Purification
Immunogen affinity purified.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Molecular Weight
27,891 Da
3D Structure
ModBase 3D Structure for P09011
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of mouse Aquaporin 0 (246-263aa NGQPEGTGEPVELKTQAL), identical to the related rat sequence, and different from the related human sequence by two amino acids.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-MIP antibody
Western Blot (WB)

Western Blot (WB) of anti-MIP antibody

Anti- MIP antibody, MBS176068, Western blotting
All lanes: Anti MIP (MBS176068) at 0.5ug/ml
Lane 1: Mouse Spleen Tissue Lysate at 50ug
Lane 2: Mouse Intestine Tissue Lysate at 50ug
Predicted bind size: 28KD
Observed bind size: 50KD
Rabbit Anti-MIP Polyclonal Antibody – Cat# MBS176068

Other Notes

Small volumes of anti-MIP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MIP purchase

MBS176068 is an antibody targeting MIP. Also known as Anti-Aquaporin 0 antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MIP. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
Lens fiber major intrinsic protein
NCBI Official Synonym Full Names
major intrinsic protein of lens fiber
NCBI Official Symbol
Mip
NCBI Official Synonym Symbols
Aqp0
UniProt Protein Name
Lens fiber major intrinsic protein
UniProt Synonym Protein Names
Aquaporin-0; MIP26; MP26
Protein Family
UniProt Gene Name
Mip
UniProt Synonym Gene Names
MP26
UniProt Entry Name
MIP_RAT
NCBI Protein Information
lens fiber major intrinsic protein; MP26; MIP26; aquaporin-0; major intrinsic protein of eye lens fiber

NCBI Summary for MIP

human homolog is a member of the aquaporin family of water transporters [RGD, Feb 2006]

UniProt Comments for MIP

AQP0: major intrinsic protein of lens fiber. A member of the water-transporting aquaporins as well as the original member of the MIP family of channel proteins. May be responsible for regulating the osmolarity of the lens. Defects in MIP are a cause of autosomal recessive congenital cataract.

Protein type: Channel, misc.; Membrane protein, multi-pass; Transporter, aquaporin family; Membrane protein, integral

Cellular Component: intracellular canaliculus; intracellular membrane-bound organelle; membrane; integral to plasma membrane; integral to membrane; plasma membrane; gap junction

Molecular Function: calmodulin binding; water channel activity; structural constituent of eye lens; glycerol channel activity

Biological Process: lens development in camera-type eye; glycerol transport; cellular water homeostasis; visual perception; canalicular bile acid transport; water transport; transmembrane transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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