Rabbit Anti-ABI2 Polyclonal Antibody – Cat# MBS176106

Anti-ABI2 antibody, MBS176106, Western blotting
Lane 1: Rat Brain Tissue Lysate
Lane 2: Human Placenta Tissue Lysate
Lane 3: MCF-7 Cell Lysate
Lane 4: HELA Cell Lysate
Lane 5: JURKAT Cell Lysate

ABI2 Antibody – Rabbit Polyclonal

Name: ABI2 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS176106
Price: 210 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS176106

Description: Rabbit IgG polyclonal antibody for Abl interactor 2(ABI2) detection. Tested with WB in Human, Mouse, Rat.Background: ABI2(ABL Interactor 2), is a protein that in humans is encoded by the ABI2 gene. By analysis of a YAC and a BAC, Machado et… More details

$210 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ABI2, Polyclonal Antibody

Full Product Name

Anti-ABI2 antibody

Product Gene Name

anti-ABI2 antibody

Product Synonym Names

Abl interactor 2; abl-interactor 2; Abelson interactor 2 antibody; ABI 2 antibody; ABI2B antibody; Abl binding protein 3 antibody; Abl interacting protein 1(SH3 containing protein) antibody; Abl interactor 2 antibody; Abl interactor protein 2b antibody; AblBP3 antibody; AIP 1 antibody; Arg binding protein 1 antibody; Arg protein tyrosine kinase binding protein antibody; ArgBP1 antibody; ARGBPIA antibody; ArgBPIB antibody; OTTHUMP00000163783 antibody; OTTHUMP00000163784 antibody; OTTHUMP00000206182 antibody; OTTHUMP00000206183 antibody; OTTHUMP00000206184 antibody; OTTHUMP00000206185 antibody; SSH3BP2 antibody

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Form/Format

Lyophilized

Purity/Purification

Immunogen affinity purified.

Preparation and Storage

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

Molecular Weight

54,819 Da

OMIM

606442

3D Structure

ModBase 3D Structure for Q9NYB9

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human ABI2 (158-173aa RFKVSTQNMKMGGLPR), identical to the related mouse and rat sequences.

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Applications Tested/Suitable for anti-ABI2 antibody

Western Blot (WB)

Other Notes

Small volumes of anti-ABI2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ABI2 purchase

MBS176106 is an antibody targeting ABI2. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ABI2. It may not necessarily be applicable to this product.

NCBI GI #

50400673

NCBI GeneID

10152

NCBI Accession #

Q9NYB9.1

UniProt Primary Accession #

Q9NYB9

UniProt Secondary Accession #

Q13147; Q13249; Q13801; Q9BV70; B4DSN1

UniProt Related Accession #

Q9NYB9

NCBI Official Full Name

Abl interactor 2

NCBI Official Synonym Full Names

abl-interactor 2

NCBI Official Symbol

ABI2

NCBI Official Synonym Symbols

ABI-2; ABI2B; AIP-1; AblBP3; argBP1; SSH3BP2; argBPIA; argBPIB

UniProt Protein Name

Abl interactor 2

UniProt Synonym Protein Names

Abelson interactor 2; Abi-2; Abl-binding protein 3; AblBP3; Arg-binding protein 1; ArgBP1

Protein Family

Abl interactor

UniProt Gene Name

ABI2

UniProt Synonym Gene Names

ARGBPIA; Abi-2; AblBP3; ArgBP1

UniProt Entry Name

ABI2_HUMAN

NCBI Protein Information

abl interactor 2; abelson interactor 2; abl binding protein 3; arg-binding protein 1; abl-interactor protein 2b; arg protein tyrosine kinase-binding protein; abl-interacting protein 1 (SH3-containing protein)

UniProt Comments for ABI2

Abi-2: May act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Regulates ABL1/c-Abl-mediated phosphorylation of MENA. Belongs to the ABI family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 2q33

Cellular Component: cytoskeleton; lamellipodium; cytoplasm; cytosol; filopodium

Molecular Function: protein binding; DNA binding; ubiquitin protein ligase binding; protein complex binding; Rac GTPase binding; cytoskeletal adaptor activity; kinase binding; SH3 domain binding

Biological Process: cell migration; peptidyl-tyrosine phosphorylation; actin polymerization and/or depolymerization; Rac protein signal transduction; cytoskeleton organization and biogenesis; cell motility

Research Articles on ABI2

1. Abl-interactor 2 (ABI2) is a novel MLL translocation partner in acute myeloid leukemia.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ABI2 antibody

Reference Product	PubMed Publications
TRIM32 antibody	>2 publications with ABI2 and TRIM32
ABL1 antibody	>1 publications with ABI2 and ABL1
WASF1 antibody	>1 publications with ABI2 and WASF1

Pathways associated with anti-ABI2 antibody

Products by Pathway	Pathway Diagram
Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway antibodies	Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram
RAC1 Signaling Pathway antibodies	RAC1 Signaling Pathway Diagram
Regulation Of Actin Cytoskeleton Pathway antibodies	Regulation Of Actin Cytoskeleton Pathway Diagram
Regulation Of Actin Cytoskeleton Pathway antibodies	Regulation Of Actin Cytoskeleton Pathway Diagram
Regulation Of Actin Cytoskeleton Pathway antibodies	Regulation Of Actin Cytoskeleton Pathway Diagram
Regulation Of Actin Dynamics For Phagocytic Cup Formation Pathway antibodies	Regulation Of Actin Dynamics For Phagocytic Cup Formation Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
Signaling By VEGF Pathway antibodies	Signaling By VEGF Pathway Diagram

Diseases associated with anti-ABI2 antibody

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>4 publications with ABI2 and Nervous System Diseases
Cell Transformation, Neoplastic Antibodies	>3 publications with ABI2 and Cell Transformation, Neoplastic
Neurobehavioral Manifestations Antibodies	>2 publications with ABI2 and Neurobehavioral Manifestations
Necrosis Antibodies	>2 publications with ABI2 and Necrosis
Neoplasm Metastasis Antibodies	>1 publications with ABI2 and Neoplasm Metastasis
Neoplasms, Experimental Antibodies	>1 publications with ABI2 and Neoplasms, Experimental
Brain Diseases Antibodies	>1 publications with ABI2 and Brain Diseases
Blood Coagulation Disorders Antibodies	>1 publications with ABI2 and Blood Coagulation Disorders
Weight Loss Antibodies	>1 publications with ABI2 and Weight Loss
Learning Disorders Antibodies	>1 publications with ABI2 and Learning Disorders

Organs/Tissues associated with anti-ABI2 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>17 publications with ABI2 and Brain
Vascular Antibodies	>10 publications with ABI2 and Vascular
Thyroid Antibodies	>9 publications with ABI2 and Thyroid
Blood Antibodies	>6 publications with ABI2 and Blood
Heart Antibodies	>4 publications with ABI2 and Heart
Muscle Antibodies	>3 publications with ABI2 and Muscle
Embryonic Tissue Antibodies	>3 publications with ABI2 and Embryonic Tissue
Eye Antibodies	>2 publications with ABI2 and Eye
Nerve Antibodies	>2 publications with ABI2 and Nerve
Bone Antibodies	>2 publications with ABI2 and Bone