Rabbit Anti-WNT2B Polyclonal Antibody – Cat# MBS176144

Anti-Wnt2b antibody, MBS176144, Western blotting
Recombinant Protein Detection Source :E.coli derived -recombinant Human WNT2B, 35.78KD(162aa tag+ R101-A254)
Lane 1: Recombinant Human WNT2B Protein 10ng
Lane 2: Recombinant Human WNT2B Protein 5ng
Lane 3: Recombinant Human WNT2B Protein 2.5ng

WNT2B Antibody – Rabbit Polyclonal

Name: WNT2B Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS176144
Price: 210 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS176144

Description: Rabbit IgG polyclonal antibody for Protein Wnt-2b(WNT2B) detection. Tested with WB in Human, Mouse, Rat.Background: WNT2B(Wingless-Type MMTV Integration Site Family Member 2B), is a protein that in humans is encoded by the WNT2B gene. This gene… More details

$210 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Wnt2b, Polyclonal Antibody

Full Product Name

Anti-Wnt2b antibody

Product Gene Name

anti-WNT2B antibody

Product Synonym Names

Protein Wnt-2b; wingless-type MMTV integration site family, member 2B; Protein Wnt-13 antibody; Protein Wnt-2b antibody; Wingless type MMTV integration site family, member 13 antibody; Wingless type MMTV integration site family, member 2B antibody; WNT13 antibody; Wnt2b antibody; WNT2B_HUMAN antibody; XWNT2 antibody; XWNT2, Xenopus, homolog of antibody

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Form/Format

Lyophilized

Purity/Purification

Immunogen affinity purified.

Preparation and Storage

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

Molecular Weight

41,830 Da

OMIM

601968

3D Structure

ModBase 3D Structure for Q93097

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human Wnt2b (169-185aa DPYTRGRHHDQRGDFDW), identical to the related rat and mouse sequences.

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Applications Tested/Suitable for anti-WNT2B antibody

Western Blot (WB)

Other Notes

Small volumes of anti-WNT2B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for WNT2B purchase

MBS176144 is an antibody targeting WNT2B. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for WNT2B. It may not necessarily be applicable to this product.

NCBI GI #

14424481

NCBI GeneID

7482

NCBI Accession #

Q93097.2

UniProt Primary Accession #

Q93097

UniProt Secondary Accession #

O14903; Q5TEH9; Q5TEI2; Q9HDC1; Q9HDC2

UniProt Related Accession #

Q93097

NCBI Official Full Name

Protein Wnt-2b

NCBI Official Synonym Full Names

wingless-type MMTV integration site family, member 2B

NCBI Official Symbol

WNT2B

NCBI Official Synonym Symbols

WNT13

UniProt Protein Name

Protein Wnt-2b

UniProt Synonym Protein Names

Protein Wnt-13

Protein Family

Protein

UniProt Gene Name

WNT2B

UniProt Synonym Gene Names

WNT13

UniProt Entry Name

WNT2B_HUMAN

NCBI Protein Information

protein Wnt-2b; XWNT2, Xenopus, homolog of; wingless-type MMTV integration site family, member 13

NCBI Summary for WNT2B

This gene encodes a member of the wingless-type MMTV integration site (WNT) family of highly conserved, secreted signaling factors. WNT family members function in a variety of developmental processes including regulation of cell growth and differentiation and are characterized by a WNT-core domain. This gene may play a role in human development as well as carcinogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

UniProt Comments for WNT2B

WNT2B: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. May be involved in normal development or differentiation as well as in carcinogenesis. Belongs to the Wnt family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 1p13

Cellular Component: extracellular space; proteinaceous extracellular matrix; extracellular region

Molecular Function: frizzled binding

Biological Process: neuron differentiation; lens development in camera-type eye; Wnt receptor signaling pathway; cell fate commitment; male gonad development; chondrocyte differentiation; Wnt receptor signaling pathway through beta-catenin; forebrain regionalization; cellular response to starvation

Research Articles on WNT2B

1. secretion of WNT2B and WNT9B and stabilization of beta-catenin (CTNNB1) upon virus infection negatively regulate expression of representative inducible genes IFNB1, IFIT1 and TNF in a CTNNB1-dependent effector mechanism

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-WNT2B antibody

Reference Product	PubMed Publications
FZD5 antibody	>10 publications with WNT2B and FZD5
FZD6 antibody	>9 publications with WNT2B and FZD6
FZD4 antibody	>9 publications with WNT2B and FZD4
SFRP1 antibody	>8 publications with WNT2B and SFRP1
FZD10 antibody	>7 publications with WNT2B and FZD10
FZD7 antibody	>7 publications with WNT2B and FZD7
FZD2 antibody	>7 publications with WNT2B and FZD2
FZD1 antibody	>6 publications with WNT2B and FZD1
FZD9 antibody	>4 publications with WNT2B and FZD9
FZD8 antibody	>4 publications with WNT2B and FZD8

Pathways associated with anti-WNT2B antibody

Products by Pathway	Pathway Diagram
Basal Cell Carcinoma Pathway antibodies	Basal Cell Carcinoma Pathway Diagram
Basal Cell Carcinoma Pathway antibodies	Basal Cell Carcinoma Pathway Diagram
Class B/2 (Secretin Family Receptors) Pathway antibodies	Class B/2 (Secretin Family Receptors) Pathway Diagram
DNA Damage Response (only ATM Dependent) Pathway antibodies	DNA Damage Response (only ATM Dependent) Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
HTLV-I Infection Pathway antibodies	HTLV-I Infection Pathway Diagram
HTLV-I Infection Pathway antibodies	HTLV-I Infection Pathway Diagram
Hedgehog Signaling Pathway antibodies	Hedgehog Signaling Pathway Diagram
Hedgehog Signaling Pathway antibodies	Hedgehog Signaling Pathway Diagram

Diseases associated with anti-WNT2B antibody

Disease Name	Pubmed Publications
Breast Neoplasms Antibodies	>8 publications with WNT2B and Breast Neoplasms
Necrosis Antibodies	>4 publications with WNT2B and Necrosis
Inflammation Antibodies	>4 publications with WNT2B and Inflammation
Disease Models, Animal Antibodies	>2 publications with WNT2B and Disease Models, Animal
Neoplasms, Experimental Antibodies	>2 publications with WNT2B and Neoplasms, Experimental
Neural Tube Defects Antibodies	>2 publications with WNT2B and Neural Tube Defects
Neoplasm Metastasis Antibodies	>2 publications with WNT2B and Neoplasm Metastasis
Ovarian Neoplasms Antibodies	>2 publications with WNT2B and Ovarian Neoplasms
Congenital Abnormalities Antibodies	>2 publications with WNT2B and Congenital Abnormalities
Brain Diseases Antibodies	>1 publications with WNT2B and Brain Diseases

Organs/Tissues associated with anti-WNT2B antibody

Organ/Tissue Name	Pubmed Publications
Embryonic Tissue Antibodies	>27 publications with WNT2B and Embryonic Tissue
Eye Antibodies	>20 publications with WNT2B and Eye
Brain Antibodies	>18 publications with WNT2B and Brain
Lung Antibodies	>18 publications with WNT2B and Lung
Kidney Antibodies	>8 publications with WNT2B and Kidney
Testis Antibodies	>6 publications with WNT2B and Testis
Skin Antibodies	>4 publications with WNT2B and Skin
Prostate Antibodies	>4 publications with WNT2B and Prostate
Placenta Antibodies	>4 publications with WNT2B and Placenta
Ovary Antibodies	>2 publications with WNT2B and Ovary