• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

NOXA1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS176147

Description: Rabbit IgG polyclonal antibody for NADPH oxidase activator 1(NOXA1) detection. Tested with WB in Human.Background: NOXA1(NADPH oxidase activator 1), also called NOX ACTIVATOR 1 or p51-NOX, is an enzyme that in humans is encoded by the NOXA1 gene.… More details

$210 / 0.01 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NOXA1, Polyclonal Antibody
Full Product Name
Anti-NOXA1 antibody
Product Gene Name
anti-NOXA1 antibody
Product Synonym Names
NADPH oxidase activator 1; NADPH oxidase activator 1; Antigen NY CO 31 antibody; Antigen NY-CO-31 antibody; FLJ25475 antibody; Inhibitory NADPH oxidase activator 1 antibody; MGC131800 antibody; NADPH oxidase activator 1 antibody; NCF2 like protein antibody; NCF2-like protein antibody; NOX activator 1 antibody; NOXA 1 antibody; Noxa1 antibody; NOXA1_HUMAN antibody; NY CO 31 antibody; p51 nox antibody; p51-nox antibody; p51NOX antibody; P67phox like factor antibody; P67phox-like factor antibody; SDCCAG31 antibody; Serologically defined colon cancer antigen 31 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Lyophilized
Purity/Purification
Immunogen affinity purified.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Molecular Weight
45,245 Da
OMIM
611255
3D Structure
ModBase 3D Structure for Q86UR1
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human NOXA1 (176-195aa RQVPRGEVFRPHRWHLKHLE).
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-NOXA1 antibody
Western Blot (WB)

Western Blot (WB) of anti-NOXA1 antibody

Anti-NOXA1 antibody, MBS176147, Western blotting
Lane 1: U87 Cell Lysate
Lane 2: HELA Cell Lysate
Rabbit Anti-NOXA1 Polyclonal Antibody – Cat# MBS176147

Other Notes

Small volumes of anti-NOXA1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NOXA1 purchase

MBS176147 is an antibody targeting NOXA1. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for NOXA1. It may not necessarily be applicable to this product.

NCBI GI #
74759404
NCBI GeneID
10811
NCBI Accession #
Q86UR1.1
UniProt Primary Accession #
Q86UR1
UniProt Secondary Accession #
O60533; Q29VU9; Q29VV0; Q2TAM1; Q8IUS3
UniProt Related Accession #
Q86UR1
NCBI Official Full Name
NADPH oxidase activator 1
NCBI Official Synonym Full Names
NADPH oxidase activator 1
NCBI Official Symbol
NOXA1
NCBI Official Synonym Symbols
p51NOX; NY-CO-31; SDCCAG31
UniProt Protein Name
NADPH oxidase activator 1
UniProt Synonym Protein Names
Antigen NY-CO-31; NCF2-like protein; P67phox-like factor; p51-nox
Protein Family
NADPH oxidase activator
UniProt Gene Name
NOXA1
UniProt Synonym Gene Names
P51NOX; NOX activator 1
UniProt Entry Name
NOXA1_HUMAN
NCBI Protein Information
NADPH oxidase activator 1; p51-nox; Nox activator 1; antigen NY-CO-31; NCF2-like protein; p67phox-like factor; inhibitory NADPH oxidase activator 1; serologically defined colon cancer antigen 31

NCBI Summary for NOXA1

This gene encodes a protein which activates NADPH oxidases, enzymes which catalyze a reaction generating reactive oxygen species. The encoded protein contains four N-terminal tetratricopeptide domains and a C-terminal Src homology 3 domain. Interaction between the encoded protein and proteins in the oxidase regulatory complex occur via the tetratricopeptide domains. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Show more

UniProt Comments for NOXA1

NOXA1: Functions as an activator of NOX1, a superoxide- producing NADPH oxidase. Functions in the production of reactive oxygen species (ROS) which participate in a variety of biological processes including host defense, hormone biosynthesis, oxygen sensing and signal transduction. May also activate CYBB/gp91phox and NOX3. Belongs to the NCF2/NOXA1 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Activator

Chromosomal Location of Human Ortholog: 9q34.3

Cellular Component: cytoplasm; NADPH oxidase complex

Molecular Function: protein binding; enzyme binding; Rac GTPase binding; superoxide-generating NADPH oxidase activator activity; SH3 domain binding

Biological Process: positive regulation of catalytic activity; superoxide metabolic process; regulation of hydrogen peroxide metabolic process
Show more

Research Articles on NOXA1

1. A NOXA1 peptide blocked NOXA1-Nox1 binding. The finding identifies a NOXA1-activating domain and an isoform-specific Nox1 inhibitor.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-NOXA1 antibody

 Reference Product  PubMed Publications
 NOXO1 antibody  >64 publications with NOXA1 and NOXO1
 NOX1 antibody  >63 publications with NOXA1 and NOX1
 RAC1 antibody  >21 publications with NOXA1 and RAC1
 CYBA antibody  >9 publications with NOXA1 and CYBA
 NCF1 antibody  >2 publications with NOXA1 and NCF1
 RAC3 antibody  >1 publications with NOXA1 and RAC3

Pathways associated with anti-NOXA1 antibody

 Products by Pathway  Pathway Diagram
 Integrated Breast Cancer Pathway antibodies  Integrated Breast Cancer Pathway Diagram
 Integrated Cancer Pathway antibodies  Integrated Cancer Pathway Diagram
 Integrated Pancreatic Cancer Pathway antibodies  Integrated Pancreatic Cancer Pathway Diagram
 Prostate Cancer Pathway antibodies  Prostate Cancer Pathway Diagram
 RAC1 Signaling Pathway antibodies  RAC1 Signaling Pathway Diagram

Diseases associated with anti-NOXA1 antibody

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >6 publications with NOXA1 and Necrosis
 Inflammation Antibodies  >4 publications with NOXA1 and Inflammation
 Disease Models, Animal Antibodies  >3 publications with NOXA1 and Disease Models, Animal
 Nervous System Diseases Antibodies  >2 publications with NOXA1 and Nervous System Diseases
 Cell Transformation, Neoplastic Antibodies  >2 publications with NOXA1 and Cell Transformation, Neoplastic
 Fibrosis Antibodies  >2 publications with NOXA1 and Fibrosis
 Fetal Alcohol Spectrum Disorders Antibodies  >2 publications with NOXA1 and Fetal Alcohol Spectrum Disorders
 Adenoma Antibodies  >1 publications with NOXA1 and Adenoma
 Kidney Neoplasms Antibodies  >1 publications with NOXA1 and Kidney Neoplasms
 Liver Diseases Antibodies  >1 publications with NOXA1 and Liver Diseases

Organs/Tissues associated with anti-NOXA1 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >9 publications with NOXA1 and Blood
 Kidney Antibodies  >7 publications with NOXA1 and Kidney
 Lung Antibodies  >5 publications with NOXA1 and Lung
 Brain Antibodies  >3 publications with NOXA1 and Brain
 Eye Antibodies  >2 publications with NOXA1 and Eye
 Embryonic Tissue Antibodies  >2 publications with NOXA1 and Embryonic Tissue
 Ovary Antibodies  >1 publications with NOXA1 and Ovary
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000