Rabbit Anti-TLR10 Polyclonal Antibody – Cat# MBS176204

Anti-TLR10 antibody, MBS176204, Western blotting
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TLR10 Antibody – Rabbit Polyclonal

Name: TLR10 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS176204
Price: 210 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS176204

Description: Rabbit IgG polyclonal antibody for Toll-like receptor 10(TLR10) detection. Tested with WB in Human.Background: TLR10(Toll-like receptor 10), is a protein that in humans is encoded by the TLR10 gene. The protein encoded by this gene is a member of… More details

$210 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TLR10, Polyclonal Antibody

Full Product Name

Anti-TLR10 antibody

Product Gene Name

anti-TLR10 antibody

Product Synonym Names

Toll-like receptor 10; toll-like receptor 10; CD 290 antibody; CD 290 antigen antibody; CD290 antibody; CD290 antigen antibody; MGC104967 antibody; MGC126398 antibody; MGC126399 antibody; OTTHUMP00000158729 antibody; OTTHUMP00000218162 antibody; TLR10 antibody; TLR10_HUMAN antibody; Toll like receptor 10 antibody; Toll-like receptor 10 antibody; UNQ315/PRO358 antibody

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Lyophilized

Purity/Purification

Immunogen affinity purified.

Preparation and Storage

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

Molecular Weight

94,564 Da

OMIM

606270

3D Structure

ModBase 3D Structure for Q9BXR5

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human TLR10 (88-102aa DLKTFEFNKELRYLD).

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Applications Tested/Suitable for anti-TLR10 antibody

Western Blot (WB)

Other Notes

Small volumes of anti-TLR10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TLR10 purchase

MBS176204 is an antibody targeting TLR10. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TLR10. It may not necessarily be applicable to this product.

NCBI GI #

116242819

NCBI GeneID

81793

NCBI Accession #

Q9BXR5.2

UniProt Primary Accession #

Q9BXR5

UniProt Secondary Accession #

Q32MI7; Q32MI8; Q5FWG4; Q6UXL3; A8K7L1; B3Y668; D1CS21; D1CS22

UniProt Related Accession #

Q9BXR5

NCBI Official Full Name

Toll-like receptor 10

NCBI Official Synonym Full Names

toll-like receptor 10

NCBI Official Symbol

TLR10

NCBI Official Synonym Symbols

CD290

UniProt Protein Name

Toll-like receptor 10

UniProt Synonym Protein Names

CD_antigen: CD290

Protein Family

Toll-like receptor

UniProt Gene Name

TLR10

UniProt Entry Name

TLR10_HUMAN

NCBI Protein Information

toll-like receptor 10

NCBI Summary for TLR10

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is most highly expressed in lymphoid tissues such as spleen, lymph node, thymus, and tonsil. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2010]

UniProt Comments for TLR10

TLR10: Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Belongs to the Toll-like receptor family.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 4p14

Cellular Component: membrane; integral to membrane; plasma membrane

Molecular Function: transmembrane receptor activity

Biological Process: toll-like receptor 5 signaling pathway; MyD88-dependent toll-like receptor signaling pathway; regulation of cytokine secretion; toll-like receptor signaling pathway; innate immune response; immune response; inflammatory response; toll-like receptor 10 signaling pathway; positive regulation of inflammatory response

Research Articles on TLR10

1. Toll-like receptor 10 is involved in induction of innate immune responses to influenza virus infection.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TLR10 antibody

Reference Product	PubMed Publications
TLR1 antibody	>93 publications with TLR10 and TLR1
TLR2 antibody	>74 publications with TLR10 and TLR2
MYD88 antibody	>9 publications with TLR10 and MYD88
FOXP3 antibody	>2 publications with TLR10 and FOXP3

Pathways associated with anti-TLR10 antibody

Products by Pathway	Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram
MyD88 Cascade Initiated On Plasma Membrane Pathway antibodies	MyD88 Cascade Initiated On Plasma Membrane Pathway Diagram
Toll Like Receptor 10 (TLR10) Cascade Pathway antibodies	Toll Like Receptor 10 (TLR10) Cascade Pathway Diagram
Toll Like Receptor 5 (TLR5) Cascade Pathway antibodies	Toll Like Receptor 5 (TLR5) Cascade Pathway Diagram
Toll-Like Receptors Cascades Pathway antibodies	Toll-Like Receptors Cascades Pathway Diagram