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BID Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS176273

Description: Rabbit IgG polyclonal antibody for BH3-interacting domain death agonist(Bid) detection. Tested with WB, IHC-P in Mouse, Rat.Background: BID(BH3-Interacting Domain Death Agonist), is a pro-apoptotic member of the Bcl-2 protein family. The BCL2… More details

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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Bid, Polyclonal Antibody
Full Product Name
Anti-Bid antibody
Product Gene Name
anti-Bid antibody
Product Synonym Names
BH3-interacting domain death agonist; BH3 interacting domain death agonist; Apoptic death agonist antibody; Apoptotic death agonist antibody; Apoptotic death agonist BID antibody; BH3 interacting domain death agonist antibody; BH3 interacting domain death agonist p11 antibody; BH3 interacting domain death agonist p13 antibody; BH3 interacting domain death agonist p15 antibody; BH3-interacting domain death agonist p11 antibody; BID antibody; BID isoform ES(1b) antibody; BID isoform L(2) antibody; BID isoform Si6 antibody; BID_HUMAN antibody; Desmocollin type 4 antibody; FP497 antibody; HGNC:1050 antibody; Human BID coding sequence antibody; MGC15319 antibody; MGC42355 antibody; p11 BID antibody; p13 BID antibody; p15 BID antibody; p22 BID antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse, Rat
Form/Format
Lyophilized
Purity/Purification
Immunogen affinity purified.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Molecular Weight
21,952 Da
3D Structure
ModBase 3D Structure for P70444
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of mouse Bid (179-195aa NQNLFSYVRNLVRNEMD), different from the related rat sequence by one amino acid.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-Bid antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin

Immunohistochemistry (IHC) of anti-Bid antibody

Anti-Bid antibody, MBS176273, IHC(P)
IHC(P): Rat Spleen Tissue
Rabbit Anti-BID Polyclonal Antibody – Cat# MBS176273

Western Blot (WB) of anti-Bid antibody

Anti-Bid antibody, MBS176273, Western blotting
All lanes: Anti Bid(MBS176273) at 0.5ug/ml
WB: Mouse Brain Tissue Lysate at 50ug
Predicted bind size: 22KD
Observed bind size: 22KD
Rabbit Anti-BID Polyclonal Antibody, Western Blot (WB) – Cat# MBS176273

Other Notes

Small volumes of anti-Bid antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Bid purchase

MBS176273 is an antibody targeting Bid. Reactive in Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Bid. It may not necessarily be applicable to this product.

NCBI GI #
88984020
NCBI GeneID
12122
NCBI Accession #
P70444.2
UniProt Primary Accession #
P70444
UniProt Secondary Accession #
Q99M39
UniProt Related Accession #
P70444
NCBI Official Full Name
BH3-interacting domain death agonist
NCBI Official Synonym Full Names
BH3 interacting domain death agonist
NCBI Official Symbol
Bid
NCBI Official Synonym Symbols
AI875481; AU022477; 2700049M22Rik
UniProt Protein Name
BH3-interacting domain death agonist
UniProt Synonym Protein Names
p22 BID; BID
Protein Family
BH3-interacting domain death agonist
UniProt Gene Name
Bid
UniProt Synonym Gene Names
BID
UniProt Entry Name
BID_MOUSE
NCBI Protein Information
BH3-interacting domain death agonist; p22 BID

UniProt Comments for Bid

BID: a pro-apoptotic member of the Bcl-2 superfamily. Targets intracellular membranes and contains a BH3 death domain. Heterodimerizes with either the pro-apoptotic protein BAX or the anti-apoptotic protein BCL2, antagonizing its protective effect. The activity of BID is regulated by Caspase 8-mediated cleavage, exposing the BH3 domain and significantly changing the surface charge and hydrophobicity, causing translocation to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced variants have been found.

Protein type: Apoptosis; Mitochondrial

Cellular Component: membrane; mitochondrion; cell; cytoplasm; intracellular; cytosol

Molecular Function: protein binding; ubiquitin protein ligase binding

Biological Process: caspase activation; release of cytochrome c from mitochondria; positive regulation of apoptosis; positive regulation of protein homooligomerization; apoptosis; DNA damage response, signal transduction; regulation of protein oligomerization; regulation of cell proliferation; regulation of apoptosis; positive regulation of protein oligomerization; apoptotic mitochondrial changes; protein targeting to mitochondrion; protein homooligomerization
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Research Articles on Bid

1. The assessment of p53 and p21 can be expensive, but it proves to be a useful tool in difficult cases. Positive reaction to p53 can be noted in both, benign and malignant ovarian tumors

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-Bid antibody

 Reference Product  PubMed Publications
 Casp8 antibody  >1183 publications with Bid and Casp8
 Bax antibody  >1124 publications with Bid and Bax
 Bcl2l1 antibody  >340 publications with Bid and Bcl2l1
 Bak1 antibody  >117 publications with Bid and Bak1
 Bcl2 antibody  >107 publications with Bid and Bcl2
 Gzmb antibody  >58 publications with Bid and Gzmb
 Gzmf antibody  >1 publications with Bid and Gzmf
 Gzmc antibody  >1 publications with Bid and Gzmc

Pathways associated with anti-Bid antibody

 Products by Pathway  Pathway Diagram
 Activation And Oligomerization Of BAK Protein Pathway antibodies  Activation And Oligomerization Of BAK Protein Pathway Diagram
 Activation Of BAD And Translocation To Mitochondria Pathway antibodies  Activation Of BAD And Translocation To Mitochondria Pathway Diagram
 Activation Of BH3-only Proteins Pathway antibodies  Activation Of BH3-only Proteins Pathway Diagram
 Activation, Myristolyation Of BID And Translocation To Mitochondria Pathway antibodies  Activation, Myristolyation Of BID And Translocation To Mitochondria Pathway Diagram
 Activation, Translocation And Oligomerization Of BAX Pathway antibodies  Activation, Translocation And Oligomerization Of BAX Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram

Diseases associated with anti-Bid antibody

 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >873 publications with Bid and Cardiovascular Diseases
 Lung Diseases Antibodies  >685 publications with Bid and Lung Diseases
 Necrosis Antibodies  >685 publications with Bid and Necrosis
 Gastrointestinal Diseases Antibodies  >640 publications with Bid and Gastrointestinal Diseases
 Nervous System Diseases Antibodies  >612 publications with Bid and Nervous System Diseases
 Pain Antibodies  >462 publications with Bid and Pain
 Heart Diseases Antibodies  >431 publications with Bid and Heart Diseases
 Adenocarcinoma Antibodies  >360 publications with Bid and Adenocarcinoma
 Diarrhea Antibodies  >343 publications with Bid and Diarrhea
 Hypertension Antibodies  >316 publications with Bid and Hypertension

Organs/Tissues associated with anti-Bid antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1864 publications with Bid and Blood
 Liver Antibodies  >576 publications with Bid and Liver
 Heart Antibodies  >530 publications with Bid and Heart
 Lung Antibodies  >522 publications with Bid and Lung
 Brain Antibodies  >378 publications with Bid and Brain
 Kidney Antibodies  >281 publications with Bid and Kidney
 Skin Antibodies  >247 publications with Bid and Skin
 Bone Antibodies  >210 publications with Bid and Bone
 Muscle Antibodies  >188 publications with Bid and Muscle
 Stomach Antibodies  >183 publications with Bid and Stomach
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