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MPG Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS176301

Description: Rabbit IgG polyclonal antibody for DNA-3-methyladenine glycosylase(MPG) detection. Tested with WB in Human, Mouse, Rat.Background: MPG(N-methylpurine-DNA glycosylase) also known as MDG, 3-METHYLADENINE DNA GLYCOSYLASE, 3MeAde DNA GLYCOSYLASE, AAG… More details

$210 / 0.01 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MPG, Polyclonal Antibody
Full Product Name
Anti-MPG antibody
Product Gene Name
anti-MPG antibody
Product Synonym Names
DNA-3-methyladenine glycosylase; N-methylpurine-DNA glycosylase; 3 alkyladenine DNA glycosylase antibody; 3-alkyladenine DNA glycosylase antibody; 3-methyladenine DNA glycosidase antibody; 3MG_HUMAN antibody; AAG antibody; ADPG antibody; Alkyladenine DNA glycosylase antibody; anpg antibody; APNG antibody; DNA 3 methyladenine glycosylase antibody; DNA-3-methyladenine glycosylase antibody; MDG antibody; Mpg antibody; N methylpurine DNA glycosirase antibody; N methylpurine DNA glycosylase antibody; N-methylpurine-DNA glycosylase antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Lyophilized
Purity/Purification
Immunogen affinity purified.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Molecular Weight
30,824 Da
OMIM
156565
3D Structure
ModBase 3D Structure for P29372
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human MPG (228-243aa NKSFDQRDLAQDEAVW), different from the related mouse sequence by two amino acids, and from related rat sequence by one amino acid.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-MPG antibody
Western Blot (WB)

Western Blot (WB) of anti-MPG antibody

Anti- MPG antibody, MBS176301, Western blotting
All lanes: Anti MPG (MBS176301) at 0.5ug/ml
Lane 1: Rat Liver Tissue Lysate at 50ug
Lane 2: HELA Whole Cell Lysate at 40ug
Lane 3: JURKAT Whole Cell Lysate at 40ug
Predicted bind size: 33KD
Observed bind size: 33KD
Rabbit Anti-MPG Polyclonal Antibody – Cat# MBS176301

Other Notes

Small volumes of anti-MPG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MPG purchase

MBS176301 is an antibody targeting MPG. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MPG. It may not necessarily be applicable to this product.

NCBI GI #
206729922
NCBI GeneID
4350
NCBI Accession #
P29372.3
UniProt Primary Accession #
P29372
UniProt Secondary Accession #
Q13770; Q15275; Q15961; Q5J9I4; Q96BZ6; Q96S33; Q9NNX5; G5E9E2
UniProt Related Accession #
P29372
NCBI Official Full Name
DNA-3-methyladenine glycosylase
NCBI Official Synonym Full Names
N-methylpurine-DNA glycosylase
NCBI Official Symbol
MPG
NCBI Official Synonym Symbols
AAG; MDG; ADPG; APNG; Mid1; anpg; PIG11; PIG16; CRA36.1
UniProt Protein Name
DNA-3-methyladenine glycosylase
UniProt Synonym Protein Names
3-alkyladenine DNA glycosylase; 3-methyladenine DNA glycosidase; ADPG; N-methylpurine-DNA glycosylase
Protein Family
DNA-3-methyladenine glycosylase
UniProt Gene Name
MPG
UniProt Synonym Gene Names
AAG; ANPG; MID1
UniProt Entry Name
3MG_HUMAN
NCBI Protein Information
DNA-3-methyladenine glycosylase; 3-alkyladenine DNA glycosylase; 3-methyladenine DNA glycosidase; proliferation-inducing protein 11; proliferation-inducing protein 16; N-methylpurine-DNA glycosylase, MPG; CRA36.1 (3-methyl-adenine DNA glycosylase); 3' end of the Mid1 gene, localized 68 kb upstream the humanzeta globin gene on 16p

UniProt Comments for MPG

MPG: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions. Belongs to the DNA glycosylase MPG family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Hydrolase; EC 3.2.2.21; Nuclear receptor co-regulator

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: nucleoplasm

Molecular Function: protein binding; alkylbase DNA N-glycosylase activity; DNA-3-methyladenine glycosylase I activity; damaged DNA binding

Biological Process: DNA dealkylation; depurination; base-excision repair, AP site formation; base-excision repair; DNA repair
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Research Articles on MPG

1. disease-stage-specific alterations in the expression of MPG may highlight a potential role for MPG in determining EAC onset and thus potentially be of clinical relevance for early disease detection and increased patient survival.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MPG antibody

 Reference Product  PubMed Publications
 APEX1 antibody  >7 publications with MPG and APEX1
 EP300 antibody  >3 publications with MPG and EP300
 NCOA1 antibody  >2 publications with MPG and NCOA1
 AGA antibody  >1 publications with MPG and AGA

Pathways associated with anti-MPG antibody

 Products by Pathway  Pathway Diagram
 Base Excision Repair Pathway antibodies  Base Excision Repair Pathway Diagram
 Base Excision Repair Pathway antibodies  Base Excision Repair Pathway Diagram
 Base Excision Repair Pathway antibodies  Base Excision Repair Pathway Diagram
 Base-Excision Repair, AP Site Formation Pathway antibodies  Base-Excision Repair, AP Site Formation Pathway Diagram
 Base-free Sugar-phosphate Removal Via The Single-nucleotide Replacement Pathway antibodies  Base-free Sugar-phosphate Removal Via The Single-nucleotide Replacement Pathway Diagram
 Cleavage Of The Damaged Purine Pathway antibodies  Cleavage Of The Damaged Purine Pathway Diagram
 DNA Repair Pathway antibodies  DNA Repair Pathway Diagram
 Depurination Pathway antibodies  Depurination Pathway Diagram
 Displacement Of DNA Glycosylase By APE1 Pathway antibodies  Displacement Of DNA Glycosylase By APE1 Pathway Diagram
 Recognition And Association Of DNA Glycosylase With Site Containing An Affected Purine Pathway antibodies  Recognition And Association Of DNA Glycosylase With Site Containing An Affected Purine Pathway Diagram

Diseases associated with anti-MPG antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >698 publications with MPG and Nervous System Diseases
 Heart Diseases Antibodies  >227 publications with MPG and Heart Diseases
 Disease Models, Animal Antibodies  >213 publications with MPG and Disease Models, Animal
 Inflammation Antibodies  >111 publications with MPG and Inflammation
 Necrosis Antibodies  >103 publications with MPG and Necrosis
 Cognition Disorders Antibodies  >83 publications with MPG and Cognition Disorders
 Memory Disorders Antibodies  >72 publications with MPG and Memory Disorders
 Kidney Diseases Antibodies  >48 publications with MPG and Kidney Diseases
 Learning Disorders Antibodies  >48 publications with MPG and Learning Disorders
 Neoplasms, Experimental Antibodies  >46 publications with MPG and Neoplasms, Experimental

Organs/Tissues associated with anti-MPG antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >2280 publications with MPG and Brain
 Blood Antibodies  >1006 publications with MPG and Blood
 Heart Antibodies  >349 publications with MPG and Heart
 Muscle Antibodies  >329 publications with MPG and Muscle
 Eye Antibodies  >276 publications with MPG and Eye
 Bone Antibodies  >189 publications with MPG and Bone
 Liver Antibodies  >142 publications with MPG and Liver
 Kidney Antibodies  >129 publications with MPG and Kidney
 Lung Antibodies  >122 publications with MPG and Lung
 Skin Antibodies  >96 publications with MPG and Skin
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