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CCR9 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS176317

Description: Rabbit IgG polyclonal antibody for C-C chemokine receptor type 9(CCR9) detection. Tested with WB in Human.Background: C-C chemokine receptor type 9, also called GPR-9-6 or CDw199, is a protein that in humans is encoded by the CCR9 gene. The… More details

$210 / 0.01 mg +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
CCR9, Polyclonal Antibody
Full Product Name
Anti-CCR9 antibody
Product Gene Name
anti-CCR9 antibody
Product Synonym Names
C-C chemokine receptor type 9; chemokine(C-C motif) receptor 9; C C chemokine receptor D6 antibody; C C chemokine receptor type 9 antibody; C C CKR 9 antibody; CC Chemokine receptor CCR10 antibody; CC CKR 9 antibody; CCBP2 antibody; CCCKR9 antibody; CCR 9 antibody; CCR9 antibody; CDw199 antibody; CDw199 antigen antibody; Chemokine(C C motif) receptor 9 antibody; Chemokine(C C motif) receptor 9, isoform CRA_a antibody; Chemokine(C-C motif) receptor 9 isoform A antibody; Chemokine C C motif receptor 9 antibody; Chemokine C C receptor 10 antibody; Chemokine CC Motif Receptor 9 antibody; Chemokine receptor CCR 9 antibody; Chemokine receptor CCR9 antibody; Chemokine-binding protein D6 antibody; Cmkbr10 antibody; CMKBR9 antibody; G protein coupled receptor 28 antibody; GPR 28 antibody; GPR 9 6 antibody; GPR28 antibody; GPR96 antibody; OTTHUMP00000164653 antibody; OTTHUMP00000164654 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Lyophilized
Purity/Purification
Immunogen affinity purified.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Molecular Weight
40,713 Da
OMIM
604738
3D Structure
ModBase 3D Structure for P51686
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human CCR9 (1-17aa MTPTDFTSPIPNMADDY).
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-CCR9 antibody
Western Blot (WB)

Western Blot (WB) of anti-CCR9 antibody

Anti-CCR9 antibody, MBS176317, Western blotting
All lanes: Anti CCR9 (MBS176317) at 0.5ug/ml
Lane 1: JURKAT Whole Cell Lysate at 40ug
Lane 2: HELA Whole Cell Lysate at 40ug
Lane 3: SMMC Whole Cell Lysate at 40ug
Predicted bind size: 42KD
Observed bind size: 42KD
Rabbit Anti-CCR9 Polyclonal Antibody – Cat# MBS176317

Other Notes

Small volumes of anti-CCR9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CCR9 purchase

MBS176317 is an antibody targeting CCR9. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CCR9. It may not necessarily be applicable to this product.

NCBI GI #
114152781
NCBI GeneID
10803
NCBI Accession #
P51686.2
UniProt Primary Accession #
P51686
UniProt Secondary Accession #
Q4VBM3; Q549E0; Q9UQQ6
UniProt Related Accession #
P51686
NCBI Official Full Name
C-C chemokine receptor type 9
NCBI Official Synonym Full Names
chemokine (C-C motif) receptor 9
NCBI Official Symbol
CCR9
NCBI Official Synonym Symbols
GPR28; CDw199; GPR-9-6; CC-CKR-9
UniProt Protein Name
C-C chemokine receptor type 9
UniProt Synonym Protein Names
G-protein coupled receptor 28; GPR-9-6; CD_antigen: CDw199
Protein Family
C-C chemokine receptor
UniProt Gene Name
CCR9
UniProt Synonym Gene Names
GPR28; C-C CKR-9; CC-CKR-9; CCR-9
UniProt Entry Name
CCR9_HUMAN
NCBI Protein Information
C-C chemokine receptor type 9; G protein-coupled receptor 28

NCBI Summary for CCR9

The protein encoded by this gene is a member of the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are key regulators of the thymocytes migration and maturation in normal and inflammation conditions. The specific ligand of this receptor is CCL25. It has been found that this gene is differentially expressed by T lymphocytes of small intestine and colon, suggested a role in the thymocytes recruitment and development that may permit functional specialization of immune responses in different segment of the gastrointestinal tract. This gene is mapped to the chemokine receptor gene cluster region. Two alternatively spliced transcript variants have been described. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
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UniProt Comments for CCR9

CCR9: Receptor for chemokine SCYA25/TECK. Subsequently transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection. Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Motility/polarity/chemotaxis; Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: cell surface; integral to plasma membrane; plasma membrane

Molecular Function: C-C chemokine receptor activity; chemokine receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; cellular defense response; immune response; chemotaxis
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Research Articles on CCR9

1. CCR9 expression is elevated in the nodal lymphomas of patients with GI involvement

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CCR9 antibody

 Reference Product  PubMed Publications
 CCL25 antibody  >136 publications with CCR9 and CCL25
 CXCL12 antibody  >26 publications with CCR9 and CXCL12
 CCL21 antibody  >12 publications with CCR9 and CCL21
 CCL20 antibody  >11 publications with CCR9 and CCL20
 CCL19 antibody  >8 publications with CCR9 and CCL19
 CCL17 antibody  >5 publications with CCR9 and CCL17
 CCL27 antibody  >3 publications with CCR9 and CCL27
 CCL22 antibody  >3 publications with CCR9 and CCL22
 CCL13 antibody  >1 publications with CCR9 and CCL13

Pathways associated with anti-CCR9 antibody

 Products by Pathway  Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram

Diseases associated with anti-CCR9 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >78 publications with CCR9 and Inflammation
 Disease Models, Animal Antibodies  >28 publications with CCR9 and Disease Models, Animal
 Necrosis Antibodies  >22 publications with CCR9 and Necrosis
 Lymphoma Antibodies  >16 publications with CCR9 and Lymphoma
 Liver Diseases Antibodies  >15 publications with CCR9 and Liver Diseases
 Hypersensitivity Antibodies  >14 publications with CCR9 and Hypersensitivity
 Carcinoma Antibodies  >10 publications with CCR9 and Carcinoma
 Neoplasms, Experimental Antibodies  >6 publications with CCR9 and Neoplasms, Experimental
 Liver Neoplasms Antibodies  >6 publications with CCR9 and Liver Neoplasms
 Breast Neoplasms Antibodies  >5 publications with CCR9 and Breast Neoplasms

Organs/Tissues associated with anti-CCR9 antibody

 Organ/Tissue Name  Pubmed Publications
 Intestine Antibodies  >141 publications with CCR9 and Intestine
 Thymus Antibodies  >87 publications with CCR9 and Thymus
 Mixed Antibodies  >4 publications with CCR9 and Mixed
 Stomach Antibodies  >4 publications with CCR9 and Stomach
 Kidney Antibodies  >3 publications with CCR9 and Kidney
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