Rabbit Anti-KLK10 Polyclonal Antibody – Cat# MBS176378

Anti-Kallikrein 10 antibody, MBS176378, Western blotting
All lanes: Anti Kallikrein 10 (MBS176378) at 0.5ug/ml
Lane 1: Rat Ovary Tissue Lysate at 50ug
Lane 2: Rat Testis Tissue Lysate at 50ug
Lane 3: Rat Spleen Tissue Lysate at 50ug
Lane 4: Rat Liver Tissue Lysate at 50ug
Lane 5: 22RV Whole Cell Lysate at 40ug
Lane 6: SROV Whole Cell Lysate at 40ug
Lane 7: HELA Whole Cell Lysate at 40ug
Lane 8: MCF-7 Whole Cell Lysate at 40ug
Lane 9: MM231 Whole Cell Lysate at 40ug
Predicted bind size: 37KD
Observed bind size: 37KD

Kallikrein 10 (KLK10) Antibody – Rabbit Polyclonal

Name: KLK10 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS176378
Price: 210 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS176378

Description: Rabbit IgG polyclonal antibody for Kallikrein-10(KLK10) detection. Tested with WB in Human.Background: KLK10(kallikrein-related peptidase 10) also known as kallikrein 10, PRSSL1 or NES1, belongs to the kallikrein subfamily of serine proteases,… More details

$210 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Kallikrein 10 (KLK10), Polyclonal Antibody

Full Product Name

Anti-Kallikrein 10 antibody

Product Gene Name

anti-KLK10 antibody

Product Synonym Names

Kallikrein-10; kallikrein-related peptidase 10; breast normal epithelial cell associated serine protease antibody; Kallikrein related peptidase 10 antibody; Kallikrein10 antibody; KLK 10 antibody; KLK10 antibody; NES 1 antibody; NES1 antibody; Normal epithelial cell specific 1 antibody; Protease serine like 1 antibody; PRSS L1 antibody; PRSSL 1 antibody; PRSSL1 antibody

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Lyophilized

Purity/Purification

Immunogen affinity purified.

Preparation and Storage

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

Molecular Weight

30,170 Da

OMIM

602673

3D Structure

ModBase 3D Structure for O43240

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human Kallikrein 10 (252-265aa SAQHPAVYTQICKY).

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Applications Tested/Suitable for anti-KLK10 antibody

Western Blot (WB)

Other Notes

Small volumes of anti-KLK10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KLK10 purchase

MBS176378 is an antibody targeting KLK10. Also known as Anti-Kallikrein 10 antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for KLK10. It may not necessarily be applicable to this product.

NCBI GI #

317373432

NCBI GeneID

5655

NCBI Accession #

O43240.3

UniProt Primary Accession #

O43240

UniProt Secondary Accession #

Q53YL3; Q99920; Q9GZW9; A6NC12

UniProt Related Accession #

O43240

NCBI Official Full Name

Kallikrein-10

NCBI Official Synonym Full Names

kallikrein-related peptidase 10

NCBI Official Symbol

KLK10

NCBI Official Synonym Symbols

NES1; PRSSL1

UniProt Protein Name

Kallikrein-10

UniProt Synonym Protein Names

Normal epithelial cell-specific 1; Protease serine-like 1

Protein Family

Glandular kallikrein

UniProt Gene Name

KLK10

UniProt Synonym Gene Names

NES1; PRSSL1

UniProt Entry Name

KLK10_HUMAN

NCBI Protein Information

kallikrein-10; protease serine-like 1; kallikrein 10 protein 1; kallikrein 10 protein 2; kallikrein 10 protein 3; kallikrein 10 protein 4; kallikrein 10 protein 7; kallikrein 10 protein 8; kallikrein 10 protein 9; kallikrein 10 protein 12; protease, serine-like, 1; normal epithelial cell-specific 1; breast normal epithelial cell associated serine protease

NCBI Summary for KLK10

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]

UniProt Comments for KLK10

KLK10: Has a tumor-suppressor role for NES1 in breast and prostate cancer. Belongs to the peptidase S1 family. Kallikrein subfamily.

Protein type: Secreted; Secreted, signal peptide; EC 3.4.21.-; Tumor suppressor; Protease

Chromosomal Location of Human Ortholog: 19q13

Cellular Component: extracellular region

Molecular Function: serine-type peptidase activity; serine-type endopeptidase activity

Biological Process: proteolysis; cell cycle

Research Articles on KLK10

1. KLK10 expression is an independent biomarker of unfavorable prognosis in patients with gastric cancer.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-KLK10 antibody

Reference Product	PubMed Publications
KLK5 antibody	>16 publications with KLK10 and KLK5
KLK7 antibody	>14 publications with KLK10 and KLK7
KLK8 antibody	>14 publications with KLK10 and KLK8
KLK11 antibody	>10 publications with KLK10 and KLK11

Diseases associated with anti-KLK10 antibody

Disease Name	Pubmed Publications
Ovarian Neoplasms Antibodies	>27 publications with KLK10 and Ovarian Neoplasms
Breast Neoplasms Antibodies	>27 publications with KLK10 and Breast Neoplasms
Lung Neoplasms Antibodies	>7 publications with KLK10 and Lung Neoplasms
Respiratory Tract Diseases Antibodies	>6 publications with KLK10 and Respiratory Tract Diseases
Stomach Neoplasms Antibodies	>6 publications with KLK10 and Stomach Neoplasms
Carcinoma, Squamous Cell Antibodies	>6 publications with KLK10 and Carcinoma, Squamous Cell
Prostatic Neoplasms Antibodies	>6 publications with KLK10 and Prostatic Neoplasms
Neoplasms, Experimental Antibodies	>5 publications with KLK10 and Neoplasms, Experimental
Immune System Diseases Antibodies	>3 publications with KLK10 and Immune System Diseases
Cell Transformation, Neoplastic Antibodies	>3 publications with KLK10 and Cell Transformation, Neoplastic

Organs/Tissues associated with anti-KLK10 antibody

Organ/Tissue Name	Pubmed Publications
Prostate Antibodies	>24 publications with KLK10 and Prostate
Lung Antibodies	>7 publications with KLK10 and Lung
Testis Antibodies	>6 publications with KLK10 and Testis
Ovary Antibodies	>5 publications with KLK10 and Ovary
Skin Antibodies	>5 publications with KLK10 and Skin
Ascites Antibodies	>3 publications with KLK10 and Ascites
Mouth Antibodies	>3 publications with KLK10 and Mouth
Brain Antibodies	>3 publications with KLK10 and Brain
Pancreas Antibodies	>3 publications with KLK10 and Pancreas
Thyroid Antibodies	>2 publications with KLK10 and Thyroid