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RGS3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS176390

Description: Rabbit IgG polyclonal antibody for Regulator of G-protein signaling 3(Rgs3) detection. Tested with WB, IHC-P in Human, Mouse, Rat.Background: RGS3(Regulator of G Protein Signaling 3), is a protein that in humans is encoded by the RGS3 gene.… More details

$210 / 0.01 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RGS3, Polyclonal Antibody
Full Product Name
Anti-RGS3 antibody
Product Gene Name
Product Synonym Names
Regulator of G-protein signaling 3; regulator of G-protein signaling 3; C2PA antibody; FLJ20370 antibody; FLJ31516 antibody; FLJ90496 antibody; PDZ RGS 3 antibody; PDZ RGS3 antibody; Regulator of G protein signaling 3 antibody; Regulator of G protein signalling 3 antibody; Regulator of G-protein signaling 3 antibody; RGP 3 antibody; RGP3 antibody; RGS 3 antibody; RGS3 antibody; RGS3_HUMAN antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Reacts with: Human, Rat
Predicted to work with: Mouse
Form/Format
Lyophilized
Purity/Purification
Immunogen affinity purified.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
3D Structure
ModBase 3D Structure for Q9DC04
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of mouse RGS3 (909-925aa DSYTREHTKENLQSITR), identical to the related rat sequence, and different from the related human sequence by two amino acids.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-Rgs3 antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin
Application Notes for anti-Rgs3 antibody
Western Blot:
Concentration: 0.1-0.5ug/ml
Tested Species: Hu, Rat
Predicted Species: Ms
Antigen Retrieval: -

Immunohistochemistry (Paraffin-embedded Section):
Concentration: 0.5-1ug/ml
Tested Species: Hu, Rat
Predicted Species: Ms
Antigen Retrieval: By Heat

Tested Species: in-house tested species with positive results.
Predicted Species: Species with positive results
By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/ paraffin sections.
Other applications have not been tested.
Optimal dilutions should be determined by end users.

Western Blot (WB) of anti-Rgs3 antibody

Anti-RGS3 antibody, MBS176390, Western blotting
Lane 1: Rat Testis Tissue Lysate
Lane 2: Rat Brain Tissue Lysate
Lane 3: Rat Spleen Tissue Lysate
Lane 4: HELA Cell Lysate
Lane 5: U87 Cell Lysate
Rabbit Anti-RGS3 Polyclonal Antibody – Cat# MBS176390

Immunohistochemistry (IHC) of anti-Rgs3 antibody

Anti-RGS3 antibody, MBS176390, IHC(P)
IHC(P): Rat Intestine Tissue
Rabbit Anti-RGS3 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS176390

Other Notes

Small volumes of anti-Rgs3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Rgs3 purchase

MBS176390 is an antibody targeting Rgs3. Reactive in Reacts with: Human, Rat
Predicted to work with: Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Rgs3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Regulator of G-protein signaling 3
NCBI Official Synonym Full Names
regulator of G-protein signaling 3
NCBI Official Symbol
Rgs3
NCBI Official Synonym Symbols
C2pa; RGS3S; PDZ-RGS3; C2PA-RGS3; 4930506N09Rik
UniProt Protein Name
Regulator of G-protein signaling 3
UniProt Synonym Protein Names
C2PA
UniProt Gene Name
Rgs3
UniProt Synonym Gene Names
RGS3
UniProt Entry Name
RGS3_MOUSE
NCBI Protein Information
regulator of G-protein signaling 3; C2 membrane binding, PDZ protein/protein interaction, ATP/GTP binding domains

UniProt Comments for Rgs3

RGS3: Down-regulates signaling from heterotrimeric G-proteins by increasing the GTPase activity of the alpha subunits, thereby driving them into their inactive GDP-bound form. Down-regulates G- protein-mediated release of inositol phosphates and activation of MAP kinases. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: GAPs; GAPs, RGS

Cellular Component: nucleoplasm; membrane; cytoplasm; plasma membrane; nucleus

Molecular Function: GTPase activator activity

Biological Process: G-protein coupled receptor protein signaling pathway; signal transduction; negative regulation of signal transduction; positive regulation of GTPase activity
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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