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Flavin Containing Monooxygenase 4 (FMO4) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS176394

Description: Rabbit IgG polyclonal antibody for Dimethylaniline monooxygenase[N-oxide-forming] 4(FMO4) detection. Tested with WB, IHC-P in Human, Mouse, Rat.Background: FMO4(Flavin-containing monooxygenase 4) also known as FMO2, FORMERLY or FMO, ADULT LIVER… More details

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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Flavin containing monooxygenase 4 (FMO4), Polyclonal Antibody
Full Product Name
Anti-Flavin containing monooxygenase 4 antibody
Product Gene Name
Product Synonym Names
Dimethylaniline monooxygenase [N-oxide-forming] 4; flavin containing monooxygenase 4; Dimethylaniline monooxygenase[N oxide forming] 4 antibody; Dimethylaniline monooxygenase[N-oxide-forming] 4 antibody; Dimethylaniline monooxygenase 4 antibody; Dimethylaniline oxidase 4 antibody; FMO 2 antibody; FMO 4 antibody; FMO2 antibody; Fmo4 antibody; FMO4_HUMAN antibody; Hepatic flavin containing monooxygenase 4 antibody; Hepatic flavin-containing monooxygenase 4 antibody; OTTHUMP00000060454 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Lyophilized
Purity/Purification
Immunogen affinity purified.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Molecular Weight
63,343 Da
OMIM
136131
3D Structure
ModBase 3D Structure for P31512
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human Flavin containing monooxygenase 4 (75-92aa HEDYPNFMNHEKFWDYLQ), different from the related rat sequence by two amino acids, and from the related mouse sequence by three amino acids.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-FMO4 antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin

Western Blot (WB) of anti-FMO4 antibody

Anti-Flavin containing monooxygenase 4 antibody, MBS176394, Western blotting
Lane 1: Rat Liver Tissue Lysate
Lane 2: Mouse Liver Tissue Lysate
Lane 3: SMMC Cell Lysate
Lane 4: HEPA Cell Lysate
Lane 5: A431 Cell Lysate
Lane 6: MCF-7 Cell Lysate
Rabbit Anti-FMO4 Polyclonal Antibody – Cat# MBS176394

Immunohistochemistry (IHC) of anti-FMO4 antibody

Anti-Flavin containing monooxygenase 4 antibody, MBS176394, IHC(P)
IHC(P): Rat Liver Tissue
Rabbit Anti-FMO4 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS176394

Other Notes

Small volumes of anti-FMO4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FMO4 purchase

MBS176394 is an antibody targeting FMO4. Also known as Anti-Flavin containing monooxygenase 4 antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for FMO4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Dimethylaniline monooxygenase
NCBI Official Synonym Full Names
flavin containing monooxygenase 4
NCBI Official Symbol
FMO4
NCBI Official Synonym Symbols
FMO2
UniProt Protein Name
Dimethylaniline monooxygenase [N-oxide-forming] 4
UniProt Synonym Protein Names
Dimethylaniline oxidase 4; Hepatic flavin-containing monooxygenase 4; FMO 4
UniProt Gene Name
FMO4
UniProt Synonym Gene Names
FMO2; FMO 4
UniProt Entry Name
FMO4_HUMAN
NCBI Protein Information
dimethylaniline monooxygenase [N-oxide-forming] 4; dimethylaniline monooxygenase [N-oxide-forming] 4; FMO 4; dimethylaniline oxidase 4; hepatic flavin-containing monooxygenase 4

NCBI Summary for FMO4

Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. [provided by RefSeq, Sep 2013]
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UniProt Comments for FMO4

FMO4: This protein is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. Belongs to the FMO family.

Protein type: Membrane protein, integral; EC 1.14.13.8; Oxidoreductase; Xenobiotic Metabolism - drug metabolism - cytochrome P450

Chromosomal Location of Human Ortholog: 1q24.3

Cellular Component: endoplasmic reticulum membrane; integral to membrane

Molecular Function: FAD binding; NADP binding; flavin-containing monooxygenase activity

Biological Process: drug catabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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