Rabbit Anti-EPB41L1 Polyclonal Antibody – Cat# MBS176901

Anti-EPB41L1 antibody, MBS176901, All Western blotting
All lanes: Anti-EPB41L1(MBS176901) at 0.5ug/ml
Lane 1: Rat Brain Tissue Lysate at 40ug
Lane 2: Mouse Brain Tissue Lysate at 40ug
Predicted bind size: 99KD
Observed bind size: 99KD

EPB41L1 Antibody – Rabbit Polyclonal

Name: EPB41L1 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS176901
Price: 210 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS176901

Description: Rabbit IgG polyclonal antibody for Band 4.1-like protein 1(EPB41L1) detection. Tested with WB in Human, Mouse, Rat.Background: Band 4.1-like protein 1 is a protein that in humans is encoded by the EPB41L1 gene. This gene is mapped to 20q11.23. It… More details

$210 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

EPB41L1, Polyclonal Antibody

Full Product Name

Anti-EPB41L1 antibody

Product Gene Name

anti-EPB41L1 antibody

Product Synonym Names

Band 4.1-like protein 1; erythrocyte membrane protein band 4.1-like 1; 4.1N antibody; Band 4.1 like protein 1 antibody; Band 4.1-like protein 1 antibody; DKFZp686H17242 antibody; EPB41L 1 antibody; Epb41l1 antibody; Erythrocyte membrane protein band 4.1 like 1 antibody; KIAA0338 antibody; MGC11072 antibody; MRD11 antibody; Neuron type nonerythroid protein 4.1 antibody; Neuronal protein 4.1 antibody; Nonerythroid protein 4.1 antibody; Nonerythroid protein 4.1, neuron type antibody; OTTHUMP00000030825 antibody; OTTHUMP00000030826 antibody; OTTHUMP00000030827 antibody; OTTHUMP00000030829 antibody

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Form/Format

Lyophilized

Purity/Purification

Immunogen affinity purified.

Preparation and Storage

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

Molecular Weight

78,831 Da

OMIM

gene 614257

3D Structure

ModBase 3D Structure for Q9H4G0

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human EPB41L1 (585-604aa QDQERDTVFLKDNHLAIERK), different from the related mouse and rat sequences by one amino acid.

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Applications Tested/Suitable for anti-EPB41L1 antibody

Western Blot (WB)

Other Notes

Small volumes of anti-EPB41L1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EPB41L1 purchase

MBS176901 is an antibody targeting EPB41L1. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for EPB41L1. It may not necessarily be applicable to this product.

NCBI GI #

14916561

NCBI GeneID

2036

NCBI Accession #

Q9H4G0.2

UniProt Primary Accession #

Q9H4G0

UniProt Secondary Accession #

O15046; Q4VXM6; Q4VXM7; Q4VXM8; Q4VXN4; Q6ZT61; Q8IUU7; Q96CV5; Q96L65

UniProt Related Accession #

Q9H4G0

NCBI Official Full Name

Band 4.1-like protein 1

NCBI Official Synonym Full Names

erythrocyte membrane protein band 4.1-like 1

NCBI Official Symbol

EPB41L1

NCBI Official Synonym Symbols

4.1N; MRD11

UniProt Protein Name

Band 4.1-like protein 1

UniProt Synonym Protein Names

Neuronal protein 4.1; 4.1N

Protein Family

Band 4.1-like protein

UniProt Gene Name

EPB41L1

UniProt Synonym Gene Names

KIAA0338; 4.1N

UniProt Entry Name

E41L1_HUMAN

NCBI Protein Information

band 4.1-like protein 1; neuronal protein 4.1; neuron-type nonerythroid protein 4.1

NCBI Summary for EPB41L1

Erythrocyte membrane protein band 4.1 (EPB41) is a multifunctional protein that mediates interactions between the erythrocyte cytoskeleton and the overlying plasma membrane. The protein encoded by this gene is a neuronally-enriched protein that is structurally similar to EPB41. The encoded protein binds and stabilizes D2 and D3 dopamine receptors at the neuronal plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

UniProt Comments for EPB41L1

EPB41L1: May function to confer stability and plasticity to neuronal membrane via multiple interactions, including the spectrin-actin-based cytoskeleton, integral membrane channels and membrane-associated guanylate kinases. Defects in EPB41L1 are the cause of mental retardation autosomal dominant type 11 (MRD11). Mental retardation is characterized by significantly below average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 20q11.2-q12

Cellular Component: cytoskeleton; extrinsic to membrane; plasma membrane; cytosol

Molecular Function: actin binding; structural molecule activity

Biological Process: synaptic transmission; cortical actin cytoskeleton organization and biogenesis

Disease: Mental Retardation, Autosomal Dominant 11

Research Articles on EPB41L1

1. Kainate receptor GluK2a post-translational modifications differentially regulate association with 4.1N to control activity-dependent receptor endocytosis

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-EPB41L1 antibody

Products by Pathway	Pathway Diagram
Glutamate Binding, Activation Of AMPA Receptors And Synaptic Plasticity Pathway antibodies	Glutamate Binding, Activation Of AMPA Receptors And Synaptic Plasticity Pathway Diagram
Neuronal System Pathway antibodies	Neuronal System Pathway Diagram
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Pathway antibodies	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Pathway Diagram
Tight Junction Pathway antibodies	Tight Junction Pathway Diagram
Tight Junction Pathway antibodies	Tight Junction Pathway Diagram
Trafficking Of AMPA Receptors Pathway antibodies	Trafficking Of AMPA Receptors Pathway Diagram
Transmission Across Chemical Synapses Pathway antibodies	Transmission Across Chemical Synapses Pathway Diagram
Trk Receptor Signaling Mediated By PI3K And PLC-gamma Pathway antibodies	Trk Receptor Signaling Mediated By PI3K And PLC-gamma Pathway Diagram

Diseases associated with anti-EPB41L1 antibody

Disease Name	Pubmed Publications
Immune System Diseases Antibodies	>7 publications with EPB41L1 and Immune System Diseases
Cell Transformation, Neoplastic Antibodies	>5 publications with EPB41L1 and Cell Transformation, Neoplastic
Skin Diseases Antibodies	>4 publications with EPB41L1 and Skin Diseases
Hyperplasia Antibodies	>3 publications with EPB41L1 and Hyperplasia
Disease Models, Animal Antibodies	>3 publications with EPB41L1 and Disease Models, Animal
Lung Neoplasms Antibodies	>3 publications with EPB41L1 and Lung Neoplasms
Breast Neoplasms Antibodies	>2 publications with EPB41L1 and Breast Neoplasms
Neoplasms, Experimental Antibodies	>2 publications with EPB41L1 and Neoplasms, Experimental
Congenital Abnormalities Antibodies	>2 publications with EPB41L1 and Congenital Abnormalities
Neoplasm Metastasis Antibodies	>2 publications with EPB41L1 and Neoplasm Metastasis

Organs/Tissues associated with anti-EPB41L1 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>62 publications with EPB41L1 and Brain
Nerve Antibodies	>30 publications with EPB41L1 and Nerve
Muscle Antibodies	>27 publications with EPB41L1 and Muscle
Kidney Antibodies	>17 publications with EPB41L1 and Kidney
Embryonic Tissue Antibodies	>12 publications with EPB41L1 and Embryonic Tissue
Lung Antibodies	>9 publications with EPB41L1 and Lung
Eye Antibodies	>8 publications with EPB41L1 and Eye
Bone Antibodies	>8 publications with EPB41L1 and Bone
Vascular Antibodies	>8 publications with EPB41L1 and Vascular
Heart Antibodies	>6 publications with EPB41L1 and Heart