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SLC1A1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS176905

Description: Rabbit IgG polyclonal antibody for Excitatory amino acid transporter 3(SLC1A1) detection. Tested with WB in Mouse, Rat.Background: Solute carrier family 1 member 1, also called SLC1A1, is a protein that in humans is encoded by the SLC1A1 gene. By… More details

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Testing Data View PDF
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Product Overview

Online Datasheet in PDF
Product Name
EAAT3 (SLC1A1), Polyclonal Antibody
Full Product Name
Anti-EAAT3 antibody
Product Gene Name
anti-SLC1A1 antibody
Product Synonym Names
Excitatory amino acid transporter 3; solute carrier family 1(neuronal/epithelial high affinity glutamate transporter, system Xag), member 1; EAA3_HUMAN antibody; EAAC 1 antibody; EAAC1 antibody; EAAT 3 antibody; Excitatory amino acid carrier 1 antibody; Excitatory amino acid carrier1 antibody; Excitatory amino acid transporter 3 antibody; Excitatory amino acid transporter3 antibody; Excitatory amino-acid carrier 1 antibody; GLUTAMATE TRANSPORTER, HIGH-AFFINITY antibody; MEAAC 1 antibody; MEAAC1 antibody; Neuronal and epithelial glutamate transporter antibody; REAAC 1 antibody; REAAC1 antibody; Slc1 a1 antibody; Slc1a 1 antibody; SLC1A1 antibody; Sodium dependent glutamate/aspartate transporter 3 antibody; Sodium-dependent glutamate/aspartate transporter 3 antibody; Solute carrier family 1(neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 antibody; SOLUTE CARRIER FAMILY 1(NEURONAL/EPITHELIAL HIGH AFFINITY GLUTAMATE TRANSPORTER), MEMBER 1 antibody; Solute carrier family 1(neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 antibody; Solute carrier family 1 member 1 antibody; Solute carrier family 1, member 1 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse, Rat
Form/Format
Lyophilized
Purity/Purification
Immunogen affinity purified.
Specificity
No cross reactivity with other proteins.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Molecular Weight
56,694 Da
3D Structure
ModBase 3D Structure for P51906
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of mouse EAAT3 (10-27aa DWRRFLRNHWLLLSTVAA), identical to the related rat sequence.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-SLC1A1 antibody
Western Blot (WB)
Application Notes for anti-SLC1A1 antibody
Western Blot
Concentration: 0.1-0.5ug/ml
Tested Species: Mouse, Rat
Tested Species: In-house tested species with positive results.

Predicted Species:
Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested.
Optimal dilutions should be determined by end users.

Western Blot (WB) of anti-SLC1A1 antibody

Anti-EAAT3 antibody, MBS176905, Western blotting
Lane 1: Rat Liver Tissue Lysate
Lane 2: Rat Heart Tissue Lysate
Lane 3: HEPA Cell Lysate
Rabbit Anti-SLC1A1 Polyclonal Antibody – Cat# MBS176905

Other Notes

Small volumes of anti-SLC1A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SLC1A1 purchase

MBS176905 is an antibody targeting SLC1A1. Also known as Anti-EAAT3 antibody. Reactive in Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC1A1. It may not necessarily be applicable to this product.

NCBI GI #
341940483
NCBI GeneID
20510
NCBI Accession #
P51906.2
UniProt Primary Accession #
P51906
UniProt Secondary Accession #
O35869; O35875; Q6P1F7
UniProt Related Accession #
P51906
NCBI Official Full Name
Excitatory amino acid transporter 3
NCBI Official Synonym Full Names
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
NCBI Official Symbol
Slc1a1
NCBI Official Synonym Symbols
EAAC1; EAAC2; EAAT3; MEAAC1; D130048G10Rik
UniProt Protein Name
Excitatory amino acid transporter 3
UniProt Synonym Protein Names
Excitatory amino-acid carrier 1; Sodium-dependent glutamate/aspartate transporter 3; Solute carrier family 1 member 1
Protein Family
Excitatory amino acid transporter
UniProt Gene Name
Slc1a1
UniProt Synonym Gene Names
Eaac1; Eaat3
UniProt Entry Name
EAA3_MOUSE
NCBI Protein Information
excitatory amino acid transporter 3; glutamate transporter mEAAC2; excitatory amino acid carrier 2; excitatory amino-acid carrier 1; solute carrier family 1, member 1; sodium-dependent glutamate/aspartate transporter 3

UniProt Comments for SLC1A1

SLC1A1: Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium. Negatively regulated by ARL6IP5. Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family. SLC1A1 subfamily.

Protein type: Membrane protein, multi-pass; Transporter, SLC family; Transporter; Membrane protein, integral

Cellular Component: membrane; apical plasma membrane; plasma membrane; integral to membrane

Molecular Function: protein binding; cysteine transmembrane transporter activity; glutamate binding; symporter activity; sodium:dicarboxylate symporter activity; glutamate:sodium symporter activity; L-glutamate transmembrane transporter activity

Biological Process: L-glutamate import; L-glutamate transport; dicarboxylic acid transport; transport; cysteine transport; protein homooligomerization
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Research Articles on SLC1A1

1. EAAT3 is upstream of PKA in a pathway to regulate GluR1 trafficking.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SLC1A1 antibody

 Reference Product  PubMed Publications
 Arl6ip5 antibody  >9 publications with SLC1A1 and Arl6ip5
 Slc7a9 antibody  >5 publications with SLC1A1 and Slc7a9
 Slc3a1 antibody  >2 publications with SLC1A1 and Slc3a1
 Slc36a1 antibody  >1 publications with SLC1A1 and Slc36a1
 Hccs antibody  >1 publications with SLC1A1 and Hccs

Pathways associated with anti-SLC1A1 antibody

 Products by Pathway  Pathway Diagram
 Glutamate Neurotransmitter Release Cycle Pathway antibodies  Glutamate Neurotransmitter Release Cycle Pathway Diagram
 Glutamatergic Synapse Pathway antibodies  Glutamatergic Synapse Pathway Diagram
 Glutamatergic Synapse Pathway antibodies  Glutamatergic Synapse Pathway Diagram
 Neuronal System Pathway antibodies  Neuronal System Pathway Diagram
 Neurotransmitter Release Cycle Pathway antibodies  Neurotransmitter Release Cycle Pathway Diagram
 Protein Digestion And Absorption Pathway antibodies  Protein Digestion And Absorption Pathway Diagram
 Protein Digestion And Absorption Pathway antibodies  Protein Digestion And Absorption Pathway Diagram
 SLC-mediated Transmembrane Transport Pathway antibodies  SLC-mediated Transmembrane Transport Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
 Transmission Across Chemical Synapses Pathway antibodies  Transmission Across Chemical Synapses Pathway Diagram

Diseases associated with anti-SLC1A1 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >76 publications with SLC1A1 and Nervous System Diseases
 Brain Diseases Antibodies  >60 publications with SLC1A1 and Brain Diseases
 Disease Models, Animal Antibodies  >35 publications with SLC1A1 and Disease Models, Animal
 Epilepsy Antibodies  >22 publications with SLC1A1 and Epilepsy
 Seizures Antibodies  >15 publications with SLC1A1 and Seizures
 Pain Antibodies  >9 publications with SLC1A1 and Pain
 Movement Disorders Antibodies  >8 publications with SLC1A1 and Movement Disorders
 Nerve Degeneration Antibodies  >6 publications with SLC1A1 and Nerve Degeneration
 Epilepsy, Temporal Lobe Antibodies  >6 publications with SLC1A1 and Epilepsy, Temporal Lobe
 Atrophy Antibodies  >6 publications with SLC1A1 and Atrophy

Organs/Tissues associated with anti-SLC1A1 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >201 publications with SLC1A1 and Brain
 Blood Antibodies  >28 publications with SLC1A1 and Blood
 Kidney Antibodies  >25 publications with SLC1A1 and Kidney
 Spinal Cord Antibodies  >24 publications with SLC1A1 and Spinal Cord
 Eye Antibodies  >21 publications with SLC1A1 and Eye
 Intestine Antibodies  >16 publications with SLC1A1 and Intestine
 Embryonic Tissue Antibodies  >5 publications with SLC1A1 and Embryonic Tissue
 Testis Antibodies  >3 publications with SLC1A1 and Testis
 Dorsal Root Ganglion Antibodies  >3 publications with SLC1A1 and Dorsal Root Ganglion
 Lung Antibodies  >2 publications with SLC1A1 and Lung
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