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FCER2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS176936

Description: Rabbit IgG polyclonal antibody for Low affinity immunoglobulin epsilon Fc receptor(FCER2) detection. Tested with WB, IHC-P in Human, Mouse, Rat.Background: CD23, also known as Fc epsilon RII, or FcepsilonRII, is the "low-affinity" receptor for… More details

$210 / 0.01 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD23 (FCER2), Polyclonal Antibody
Full Product Name
Anti-CD23 Antibody
Product Gene Name
anti-FCER2 antibody
Product Synonym Names
Low affinity immunoglobulin epsilon Fc receptor; Fc fragment of IgE, low affinity II, receptor for (CD23); Blast 2 antibody; BLAST-2 antibody; Blast2 antibody; C type lectin domain family 4 member J antibody; C-type lectin domain family 4 member J antibody; C-type lectin domain family 4, member J antibody; CD 23 antibody; CD 23A antibody; CD23 antibody; CD23 antigen antibody; CD23A antibody; CLEC 4J antibody; CLEC4J antibody; Fc epsilon RII antibody; Fc fragment of IgE low affinity II receptor for antibody; Fc fragment of IgE, low affinity II, receptor for (CD23) antibody; Fc of IgE, low affinity II, receptor for (CD23) antibody; Fc receptor IgE low affinity II alpha polypeptide antibody; Fc receptor, IgE, low affinity II, alpha polypeptide, isoform CRA_a antibody; Fc-epsilon-RII antibody; FCE 2 antibody; FCE2 antibody; FCER 2 antibody; Fcer2 antibody; FCER2_HUMAN antibody; FCER2A antibody; FceRII antibody; IgE binding factor antibody; IgE receptor lymphocyte antibody; IgE-binding factor antibody; IGEBF antibody; Immunoglobulin E binding factor antibody; Immunoglobulin E receptor, low affinity II antibody; Immunoglobulin E-binding factor antibody; LEUKOCYTE ANTIGEN CD23 antibody; Low Affinity IgE Receptor antibody; Low affinity immunoglobulin epsilon Fc receptor antibody; Low affinity immunoglobulin epsilon Fc receptor membrane bound form antibody; Low affinity immunoglobulin epsilon Fc receptor soluble form antibody; Ly-42 antibody; Ly42 antibody; Lymphocyte antigen CD23 antibody; Lymphocyte IgE receptor antibody; MGC93219 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Lyophilized
Purity/Purification
Immunogen affinity purified.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
3D Structure
ModBase 3D Structure for P20693
Immunogen
E Coli-derived mouse CD23 recombinant protein (Position: E50-P331). Mouse CD23 shares 52% amino acid (aa) sequence identity with human CD23.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-FCER2 antibody
Western Blot (WB), Immunohistochemistry (Paraffin-embedded Section) (IHC-P), Immunohistochemistry (frozen section) (IHC-F), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC), ELISA
Application Notes for anti-FCER2 antibody
WB: Concentration: 0.1-0.5ug/ml; Tested Species: Mouse, Rat
IHC-P: Concentration: 0.5-1ug/ml; Tested Species: Human, Mouse, Rat; Antigen Retrieval; By Heat
IHC-F: Concentration: 0.5-1ug/ml; Tested Species: Mouse
ICC: Concentration: 0.5-1ug/ml; Tested Species: Human
IF: Concentration: 2ug/ml; Tested Species: Mouse
FC: Concentration: 1-3ug/1x106 cell; Tested Species: Human
ELISA: Concentration: 1-5ug/ml; Tested Species: Mouse

WB: The detection limit for CD23 is approximately 0.25ng/lane under reducing conditions.
Tested Species: In house tested species with positive results.
By Heat: Boiling the paraffin sections in 1mM citrate buffer, pH6.0, for 20mins is required for staining of formalin/paraffin sections.
Other applications have not been tested.

Immunohistochemistry (IHC) of anti-FCER2 antibody

Anti-CD23 Picoband antibody, MBS176936-1.JPG
IHC(P): Human Tonsil Tissue
Rabbit Anti-FCER2 Polyclonal Antibody – Cat# MBS176936

Immunohistochemistry (IHC) of anti-FCER2 antibody

Anti-CD23 Picoband antibody, MBS176936-2.JPG
IHC(P): Mouse Spleen Tissue
Rabbit Anti-FCER2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS176936

Immunohistochemistry (IHC) of anti-FCER2 antibody

Anti-CD23 Picoband antibody, MBS176936-3.JPG
IHC(P): Rat Spleen Tissue
Rabbit Anti-FCER2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS176936

Western Blot (WB) of anti-FCER2 antibody

Anti-CD23 Picoband antibody, MBS176936-4.jpg
All lanes: Anti-CD23(MBS176936) at 0.5ug/ml
WB: Mouse Liver Tissue Lysate at 40ug
Predicted bind size: 37KD
Observed bind size: 37KD
Rabbit Anti-FCER2 Polyclonal Antibody, Western Blot (WB) – Cat# MBS176936

Other Notes

Small volumes of anti-FCER2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FCER2 purchase

MBS176936 is an antibody targeting FCER2. Also known as Anti-CD23 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for FCER2. It may not necessarily be applicable to this product.

NCBI GI #
119863
NCBI GeneID
14128
NCBI Accession #
P20693.1
UniProt Primary Accession #
P20693
UniProt Secondary Accession #
Q61556; Q61557
UniProt Related Accession #
P20693
NCBI Official Full Name
Low affinity immunoglobulin epsilon Fc receptor
NCBI Official Synonym Full Names
Fc receptor, IgE, low affinity II, alpha polypeptide
NCBI Official Symbol
Fcer2a
NCBI Official Synonym Symbols
CD23; Fce2; Fcer2; Ly-42
UniProt Protein Name
Low affinity immunoglobulin epsilon Fc receptor
UniProt Synonym Protein Names
Fc-epsilon-RII; Lymphocyte IgE receptor; CD_antigen: CD23
Protein Family
Low affinity immunoglobulin epsilon Fc receptor
UniProt Gene Name
Fcer2
UniProt Synonym Gene Names
Fcer2a
UniProt Entry Name
FCER2_MOUSE
NCBI Protein Information
low affinity immunoglobulin epsilon Fc receptor; FC epsilon RII; fc-epsilon-RII; lymphocyte IgE receptor; low-affinity IgE receptor

UniProt Comments for FCER2

FCER2: Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).

Protein type: Membrane protein, integral

Cellular Component: membrane; plasma membrane; integral to membrane; external side of plasma membrane

Molecular Function: metal ion binding; IgE binding; carbohydrate binding

Biological Process: positive regulation of humoral immune response mediated by circulating immunoglobulin; positive regulation of nitric-oxide synthase activity; positive regulation of killing of cells of another organism; positive regulation of nitric-oxide synthase biosynthetic process
Show more

Research Articles on FCER2

1. CD23 was shown to be sorted in an ADAM10-dependent manner into exosomes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-FCER2 antibody

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