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Cadherin-2/N-Cadherin (CDH2) ELISA Kit for Mouse

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS177305

Principle of the assay: mouse Cadherin-2 ELISA Kit was based on standard sandwich enzyme-linked immune-sorbent assay technology. A monoclonal antibody from rat specific for Cadherin-2 has been precoated onto 96-well plates. Standards(NSO, D160-A724) and test… More details

$635 / 96-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Cadherin-2/N-Cadherin (CDH2), ELISA Kit
Full Product Name
Mouse Cadherin-2/N-Cadherin PicoKine ELISA Kit
Product Gene Name
CDH2 elisa kit
Product Synonym Names
Cadherin-2; cadherin 2, type 1, N-cadherin (neuronal); CDw325; CDHN; Neural cadherin; N-cadherin; CD325
Species Reactivity
Mouse
Assay Type
Sandwich
Samples
Cell culture supernates, serum and plasma (heparin, EDTA)
Detection Range
0.78ng/ml-50ng/ml
Sensitivity
< 20pg/ml
Specificity
Natural and recombinant mouse Cadherin-2
Preparation and Storage
Store at 4 degree C for 6 months, at -20 degree C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
Inter-assay Precision
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision.
Intra-assay Precision
Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision.
Molecular Weight
99,796 Da
3D Structure
ModBase 3D Structure for P15116
Production Time
Due to severe delay and raw materials shortage, production time may takes between 5-8 weeks.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Typical Testing Data/Standard Curve (for reference only) of CDH2 elisa kit

Mouse Cadherin-2/N-Cadherin PicoKine ELISA Kit standard curve
Mouse CDH2 ELISA Kit – Cat# MBS177305

Other Notes

Small volumes of CDH2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CDH2 purchase

MBS177305 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Cadherin-2/N-Cadherin (CDH2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CDH2. The ELISA analytical biochemical technique of the MBS177305 kit is based on CDH2 antibody-CDH2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CDH2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CDH2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for CDH2. It may not necessarily be applicable to this product.

NCBI GI #
341940300
NCBI GeneID
12558
NCBI Accession #
P15116.2
UniProt Primary Accession #
P15116
UniProt Secondary Accession #
Q64260; Q6GU11
UniProt Related Accession #
P15116
NCBI Official Full Name
Cadherin-2
NCBI Official Synonym Full Names
cadherin 2
NCBI Official Symbol
Cdh2
NCBI Official Synonym Symbols
CDHN; Ncad; N-cadherin
UniProt Protein Name
Cadherin-2
UniProt Synonym Protein Names
Neural cadherin; N-cadherin; CD_antigen: CD325
Protein Family
Cadherin
UniProt Gene Name
Cdh2
UniProt Synonym Gene Names
N-cadherin
UniProt Entry Name
CADH2_MOUSE
NCBI Protein Information
cadherin-2; neural cadherin

UniProt Comments for CDH2

CDH2: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density. Interacts with CDCP1. Identified in a complex containing FGFR4, NCAM1, CDH2, PLCG1, FRS2, SRC, SHC1, GAP43 and CTTN. Interacts with PCDH8; this complex may also include TAOK2. The interaction with PCDH8 may lead to internalization through TAOK2/p38 MAPK pathway.

Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; Cell adhesion

Cellular Component: focal adhesion; protein complex; basolateral plasma membrane; T-tubule; integral to membrane; fascia adherens; intercellular junction; catenin complex; adherens junction; cell-cell adherens junction; membrane; lamellipodium; apical plasma membrane; plasma membrane; synapse

Molecular Function: protein binding; enzyme binding; metal ion binding; gamma-catenin binding; protein complex binding; beta-catenin binding; calcium ion binding; nitric-oxide synthase binding; protein kinase binding; protein phosphatase binding; alpha-catenin binding

Biological Process: cell migration; regulation of myelination; protein heterooligomerization; regulation of signal transduction; regulation of axonogenesis; heterophilic cell adhesion; cell-cell adhesion; synaptogenesis; glial cell differentiation; regulation of protein localization; positive regulation of MAPKKK cascade; calcium-dependent cell-cell adhesion; regulation of Rho protein signal transduction; blood vessel morphogenesis; striated muscle cell differentiation; homophilic cell adhesion; cell adhesion
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Research Articles on CDH2

1. This study showed that the adherens junction proteins afadin and CDH2 are critical for the control of cell proliferation in the dorsal telencephalon and for the formation of its normal laminar structure. Inactivation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with CDH2 elisa kit

 Products by Pathway  Pathway Diagram
 Adherens Junctions Interactions Pathway antibodies  Adherens Junctions Interactions Pathway Diagram
 Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway antibodies  Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway Diagram
 Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway antibodies  Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway Diagram
 CDO In Myogenesis Pathway antibodies  CDO In Myogenesis Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Junction Organization Pathway antibodies  Cell Junction Organization Pathway Diagram
 Cell-Cell Communication Pathway antibodies  Cell-Cell Communication Pathway Diagram
 Cell-cell Junction Organization Pathway antibodies  Cell-cell Junction Organization Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram

Diseases associated with CDH2 elisa kit

 Disease Name  Pubmed Publications
 Neoplasm Metastasis Antibodies  >39 publications with CDH2 and Neoplasm Metastasis
 Disease Progression Antibodies  >30 publications with CDH2 and Disease Progression
 Breast Neoplasms Antibodies  >25 publications with CDH2 and Breast Neoplasms
 Lung Neoplasms Antibodies  >22 publications with CDH2 and Lung Neoplasms
 Cardiovascular Diseases Antibodies  >19 publications with CDH2 and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >19 publications with CDH2 and Disease Models, Animal
 Heart Diseases Antibodies  >14 publications with CDH2 and Heart Diseases
 Prostatic Neoplasms Antibodies  >13 publications with CDH2 and Prostatic Neoplasms
 Liver Diseases Antibodies  >12 publications with CDH2 and Liver Diseases
 Neoplasms, Experimental Antibodies  >12 publications with CDH2 and Neoplasms, Experimental

Organs/Tissues associated with CDH2 elisa kit

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >49 publications with CDH2 and Brain
 Embryonic Tissue Antibodies  >42 publications with CDH2 and Embryonic Tissue
 Heart Antibodies  >34 publications with CDH2 and Heart
 Bone Antibodies  >30 publications with CDH2 and Bone
 Lung Antibodies  >30 publications with CDH2 and Lung
 Eye Antibodies  >22 publications with CDH2 and Eye
 Liver Antibodies  >20 publications with CDH2 and Liver
 Prostate Antibodies  >16 publications with CDH2 and Prostate
 Testis Antibodies  >14 publications with CDH2 and Testis
 Kidney Antibodies  >14 publications with CDH2 and Kidney
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