Rat CXCL3 PicoKine ELISA Kit standard curve

C-X-C Motif Chemokine 3 (CXCL3) ELISA Kit for Rat

Name: Rat CXCL3 ELISA Kit; C-X-C Motif Chemokine 3; MyBioSource
Brand: MyBioSource
SKU: MBS177540
Price: 635 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS177540

Description: Sandwich ELISA kit of Quantitative Detection for Rat CXCL3Background: Chemokine (C-X-C motif) ligand 3 (CXCL3) is a small cytokine belonging to the CXC chemokine family. It is mapped to 14p2 in rat. CXCL3 controls migration and adhesion of… More details

$635 / 96-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

C-X-C motif chemokine 3 (CXCL3), ELISA Kit

Full Product Name

Rat CXCL3 PicoKine ELISA Kit

Product Gene Name

CXCL3 elisa kit

Product Synonym Names

C-X-C motif chemokine 3; Chemokine (CXC motif) ligand 3; Cinc 2; CINC 2b; Cinc2; CINC2b; CXCL 3; Cxcl3; CXCL3_HUMAN; Cytokine induced neutrophil chemoattractant 2; Dcip1; Dendritic cell inflammatory protein 1; Gm1960; GRO protein gamma; GRO-gamma; GRO-gamma(1-73); GRO-gamma(5-73); GRO3; GRO3 oncogene; GROG; Growth regulated protein gamma; Growth-regulated protein gamma; Macrophage inflammatory protein 2 beta precursor; Macrophage inflammatory protein 2-beta; Melanoma growth stimulatory activity gamma; Member 3; MGSA gamma; MIP 2b; MIP2-beta; MIP2B; SCYB3; Small inducible cytokine subfamily B; chemokine (C-X-C motif) ligand 3

Species Reactivity

Rat. There is no detectable cross-reactivity with other relevant proteins.

Assay Type

Sandwich

Samples

Cell culture supernates, serum and plasma (heparin, EDTA)

Sensitivity

<10pg/ml

Preparation and Storage

Store at 4 degree C for 6 months, at -20 degree C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)

Molecular Weight

10,989 Da

3D Structure

ModBase 3D Structure for Q10746

Production Time

Due to severe delay and raw materials shortage, production time may takes between 5-8 weeks.

Immunogen

E.coli, R33-S101

Intra-Assay Precision

Sample 1: n=16; Mean(pg/ml): 170; Standard deviation: 13.26; CV(%): 7.8 Sample 2: n=16; Mean(pg/ml): 375; Standard deviation: 19.5; CV(%): 5.2 Sample 3: n=16; Mean(pg/ml): 602; Standard deviation: 27.09; CV(%): 4.5

Inter-Assay Precision

Sample 1: n=24; Mean(pg/ml): 161; Standard deviation: 13.36; CV(%): 8.3 Sample 2: n=24; Mean(pg/ml): 352; Standard deviation: 22.53; CV(%): 6.4 Sample 3: n=24; Mean(pg/ml): 593; Standard deviation: 27.87; CV(%): 4.7

Assay Range

15.6pg/ml-1000pg/ml

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of CXCL3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CXCL3 purchase

MBS177540 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the C-X-C motif chemokine 3 (CXCL3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CXCL3. The ELISA analytical biochemical technique of the MBS177540 kit is based on CXCL3 antibody-CXCL3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CXCL3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CXCL3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for CXCL3. It may not necessarily be applicable to this product.

NCBI GI #

19924051

NCBI GeneID

171551

NCBI Accession #

NP_612531.1

UniProt Primary Accession #

Q10746

UniProt Secondary Accession #

Q10747; Q5CZ55; Q9EP62

UniProt Related Accession #

Q10746

GenBank Nucleotide #

NM_138522.1

NCBI Official Full Name

C-X-C motif chemokine 3

NCBI Official Synonym Full Names

chemokine (C-X-C motif) ligand 3

NCBI Official Symbol

Cxcl3

NCBI Official Synonym Symbols

Cinc2; Cinc-2; Gm1960

UniProt Protein Name

C-X-C motif chemokine 3

UniProt Synonym Protein Names

Cytokine-induced neutrophil chemoattractant 2; CINC-2; Macrophage inflammatory protein 2-alpha/beta; MIP2-alpha/beta

Protein Family

C-X-C motif chemokine

UniProt Gene Name

Cxcl3

UniProt Synonym Gene Names

Cinc2; CINC-2; MIP2-alpha/beta

UniProt Entry Name

CXCL3_RAT

NCBI Protein Information

C-X-C motif chemokine 3; MIP2-alpha/beta; macrophage inflammatory protein 2-alpha/beta; cytokine-induced neutrophil chemoattractant 2; cytokine-induced neutrophil chemoattractant-2

NCBI Summary for CXCL3

acts as a chemoattractant for neutrophils; involved in the inflammatory response [RGD, Feb 2006]

UniProt Comments for CXCL3

CXCL1: Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO- alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity. Belongs to the intercrine alpha (chemokine CxC) family.

Protein type: Secreted; Motility/polarity/chemotaxis; Secreted, signal peptide

Cellular Component: extracellular space; extracellular region

Molecular Function: chemokine activity; CXCR chemokine receptor binding

Biological Process: neutrophil chemotaxis; G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; immune response; response to lipopolysaccharide; hemopoiesis; positive regulation of leukocyte chemotaxis; chemotaxis; inflammatory response; regulation of cell proliferation

Research Articles on CXCL3

1. The decreased serum concentration of CINC-1 as neuroprotective agent and increased CINC-2alpha in late stage of Morris hepatoma may be considered for their contribution to cerebellar degeneration.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with CXCL3 elisa kit

Products by Pathway	Pathway Diagram
Chemokine Receptors Bind Chemokines Pathway antibodies	Chemokine Receptors Bind Chemokines Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
Cytokines And Inflammatory Response (BioCarta) Pathway antibodies	Cytokines And Inflammatory Response (BioCarta) Pathway Diagram
Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies	Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
G Alpha (i) Signalling Events Pathway antibodies	G Alpha (i) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram

Diseases associated with CXCL3 elisa kit

Disease Name	Pubmed Publications
Inflammation Antibodies	>73 publications with CXCL3 and Inflammation
Necrosis Antibodies	>34 publications with CXCL3 and Necrosis
Respiratory Tract Diseases Antibodies	>13 publications with CXCL3 and Respiratory Tract Diseases
Lung Diseases Antibodies	>13 publications with CXCL3 and Lung Diseases
Immune System Diseases Antibodies	>11 publications with CXCL3 and Immune System Diseases
Skin Diseases Antibodies	>9 publications with CXCL3 and Skin Diseases
Disease Models, Animal Antibodies	>7 publications with CXCL3 and Disease Models, Animal
Death Antibodies	>7 publications with CXCL3 and Death
Fibrosis Antibodies	>6 publications with CXCL3 and Fibrosis
Kidney Diseases Antibodies	>4 publications with CXCL3 and Kidney Diseases

Organs/Tissues associated with CXCL3 elisa kit

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>16 publications with CXCL3 and Lung
Eye Antibodies	>4 publications with CXCL3 and Eye
Connective Tissue Antibodies	>4 publications with CXCL3 and Connective Tissue