Human IL-34 PicoKine ELISA Kit standard curve

Interleukin-34 (IL34) ELISA Kit for Human

Name: Human IL34 ELISA Kit; Interleukin-34; MyBioSource
Brand: MyBioSource
SKU: MBS177552
Price: 635 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS177552

Description: Sandwich ELISA kit of Quantitative Detection for Human IL-34Background: Interleukin-34, or IL-34 is a protein belonging to a group of cytokines called interleukins. It is mapped to 16q22.1. The discovery of IL-34 protein in the red pulp of the… More details

$635 / 96-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Interleukin-34 (IL34), ELISA Kit

Full Product Name

Human IL-34 PicoKine ELISA Kit

Product Gene Name

IL34 elisa kit

Product Synonym Names

C16orf77; Chromosome 16 open reading frame 77; FPT025; IL 34; IL-34; IL34; IL34_HUMAN; Interleukin 34; Interleukin-34; Interleukin34; MGC34647; interleukin 34

Species Reactivity

Human. There is no detectable cross-reactivity with other relevant proteins.

Assay Type

Sandwich

Samples

Cell culture supernates, serum and plasma (heparin, EDTA)

Sensitivity

<10pg/ml

Preparation and Storage

Store at 4 degree C for 6 months, at -20 degree C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)

Molecular Weight

27,354 Da

OMIM

612081

3D Structure

ModBase 3D Structure for Q6ZMJ4

Production Time

Due to severe delay and raw materials shortage, production time may takes between 5-8 weeks.

Immunogen

E.coli, N21-P242

Intra-Assay Precision

Sample 1: n=16; Mean(pg/ml): 514; Standard deviation: 23.13; CV(%): 4.5 Sample 2: n=16; Mean(pg/ml): 1680; Standard deviation: 65.52; CV(%): 3.9 Sample 3: n=16; Mean(pg/ml): 2641; Standard deviation: 97.72; CV(%): 3.7

Inter-Assay Precision

Sample 1: n=24; Mean(pg/ml): 535; Standard deviation: 33.17; CV(%): 6.2 Sample 2: n=24; Mean(pg/ml): 1693; Standard deviation: 103.3; CV(%): 6.1 Sample 3: n=24; Mean(pg/ml): 2709; Standard deviation: 130; CV(%): 4.8

Assay Range

62.5pg/ml-4000pg/ml

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of IL34 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL34 purchase

MBS177552 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Interleukin-34 (IL34) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing IL34. The ELISA analytical biochemical technique of the MBS177552 kit is based on IL34 antibody-IL34 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IL34 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IL34. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for IL34. It may not necessarily be applicable to this product.

NCBI GI #

289666750

NCBI GeneID

146433

NCBI Accession #

NP_001166242.1

UniProt Primary Accession #

Q6ZMJ4

UniProt Secondary Accession #

Q8N6L2; B2RC28; B2Z4A8; B2ZC70

UniProt Related Accession #

Q6ZMJ4

GenBank Nucleotide #

NM_001172771.1

NCBI Official Full Name

interleukin-34 isoform 2

NCBI Official Synonym Full Names

interleukin 34

NCBI Official Symbol

IL34

NCBI Official Synonym Symbols

IL-34; C16orf77

UniProt Protein Name

Interleukin-34

Protein Family

Interleukin

UniProt Gene Name

IL34

UniProt Synonym Gene Names

C16orf77; IL-34

UniProt Entry Name

IL34_HUMAN

NCBI Protein Information

interleukin-34

NCBI Summary for IL34

Interleukin-34 is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor (CSF1R; MIM 164770) (Lin et al., 2008 [PubMed 18467591]).[supplied by OMIM, May 2008]

UniProt Comments for IL34

IL34: Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1. Belongs to the IL-34 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation; Secreted; Cytokine; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 16q22.1

Cellular Component: extracellular space

Molecular Function: growth factor activity; cytokine activity; macrophage colony stimulating factor receptor binding

Biological Process: positive regulation of cell proliferation; innate immune response; positive regulation of protein amino acid phosphorylation; inflammatory response

Research Articles on IL34

1. IL-34 is associated with insulin resistance.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with IL34 elisa kit

Reference Product	PubMed Publications
CSF1R elisa kit	>4 publications with IL34 and CSF1R

Diseases associated with IL34 elisa kit

Disease Name	Pubmed Publications
Necrosis Antibodies	>1 publications with IL34 and Necrosis

Organs/Tissues associated with IL34 elisa kit

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>3 publications with IL34 and Bone
Embryonic Tissue Antibodies	>2 publications with IL34 and Embryonic Tissue
Skin Antibodies	>1 publications with IL34 and Skin
Brain Antibodies	>1 publications with IL34 and Brain