Anti-G-CSF Polyclonal Antibody – Cat# MBS177663

Anti- G-CSF Picoband antibody, MBS177663, Western blotting
All lanes: Anti G-CSF (MBS177663) at 0.5ug/ml
WB: HELA Whole Cell Lysate at 40ug
Predicted bind size: 22KD
Observed bind size: 22KD

G-CSF Antibody – Polyclonal

Name: G-CSF Antibody; Polyclonal; Human/Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS177663
Price: 210 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS177663

Description: Rabbit IgG polyclonal antibody for Granulocyte colony-stimulating factor(CSF3) detection. Tested with WB, ELISA in Human;Mouse.Background: Granulocyte-colony stimulating factor (G-CSF or GCSF), also known as colony-stimulating factor 3 (CSF 3),… More details

$210 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

G-CSF, Polyclonal Antibody

Full Product Name

Anti-G-CSF Antibody

Product Gene Name

anti-G-CSF antibody

Product Synonym Names

Granulocyte colony-stimulating factor; C17orf33; Colony stimulating factor 3 (granulocyte); CSF 3; CSF beta; CSF3; CSF3_HUMAN; CSF3OS; Csfg; Filgrastim; G-CSF; GCSA; GCSF; Granulocyte colony stimulating factor; Granulocyte colony-stimulating factor; Lenograstim; Macrophage granulocyte inducer 2; MGC45931; MGI 2; Pluripoietin; colony stimulating factor 3 (granulocyte)

Clonality

Polyclonal

Species Reactivity

Human, Mouse

Form/Format

Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purity/Purification

Immunogen Affinity Purified

Preparation and Storage

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquoted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

Molecular Weight

22,421 Da

3D Structure

ModBase 3D Structure for P09920

Immunogen

E Coli-derived mouse G-CSF recombinant protein (Position: R47-A208). Mouse G-CSF shares 77.2% amino acid (aa) sequence identity with human G-CSF.

Ig Type

Rabbit IgG

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Applications Tested/Suitable for anti-G-CSF antibody

Western Blot (WB), ELISA (EIA)

Application Notes for anti-G-CSF antibody

ELISA Concentration: 0.1-0.5ug/ml
Western Blot Concentration: 0.1-0.5ug/ml

Product References and Citations for anti-G-CSF antibody

1. Metcalf D (July 1985). "The granulocyte-macrophage colony-stimulating factors". Science 229 (4708): 16-22. 2. Nagata S, Tsuchiya M, Asano S, Kaziro Y, Yamazaki T, Yamamoto O, Hirata Y, Kubota N, Oheda M, Nomura H (1986). "Molecular cloning and expression of cDNA for human granulocyte colony-stimulating factor". Nature 319 (6052): 415-8. 3. Souza LM, Boone TC, Gabrilove J, Lai PH, Zsebo KM, Murdock DC, Chazin VR, Bruszewski J, Lu H, Chen KK, Barendt J, Platzer, E, Moore, MAS, Mertelsmann R, Welte K (April 1986). "Recombinant human granulocyte colony-stimulating factor: effects on normal and leukemic myeloid cells". Science 232 (4746): 61-5.

Other Notes

Small volumes of anti-G-CSF antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for G-CSF purchase

MBS177663 is an antibody targeting G-CSF. Reactive in Human, Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for G-CSF. It may not necessarily be applicable to this product.

NCBI GI #

6753536

NCBI GeneID

12985

NCBI Accession #

NP_034101.1

UniProt Primary Accession #

P09920

UniProt Related Accession #

P09920

GenBank Nucleotide #

NM_009971.1

NCBI Official Full Name

granulocyte colony-stimulating factor

NCBI Official Synonym Full Names

colony stimulating factor 3 (granulocyte)

NCBI Official Symbol

Csf3

NCBI Official Synonym Symbols

Csfg; G-CSF; MGI-IG

UniProt Protein Name

Granulocyte colony-stimulating factor

Protein Family

Granulocyte colony-stimulating factor receptor

UniProt Gene Name

Csf3

UniProt Synonym Gene Names

Csfg; G-CSF

UniProt Entry Name

CSF3_MOUSE

NCBI Protein Information

granulocyte colony-stimulating factor

UniProt Comments for G-CSF

G-CSF: Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes. Belongs to the IL-6 superfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytokine; Cell cycle regulation; Secreted, signal peptide; Secreted

Cellular Component: extracellular region; extracellular space

Molecular Function: cytokine activity; enzyme binding; granulocyte colony-stimulating factor receptor binding; growth factor activity

Biological Process: granulocyte differentiation; immune response; positive regulation of actin filament polymerization; positive regulation of cell proliferation; positive regulation of myeloid cell differentiation; positive regulation of peptidyl-serine phosphorylation; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of phosphoinositide 3-kinase cascade; positive regulation of protein binding; positive regulation of protein kinase B signaling cascade; positive regulation of transcription factor import into nucleus; positive regulation of transcription from RNA polymerase II promoter

Research Articles on G-CSF

1. rapidly induces autophagy after spinal cord injury to inhibit neuronal apoptosis

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-G-CSF antibody

Products by Pathway	Pathway Diagram
Cytokine Signaling In Immune System Pathway antibodies	Cytokine Signaling In Immune System Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokines And Inflammatory Response (BioCarta) Pathway antibodies	Cytokines And Inflammatory Response (BioCarta) Pathway Diagram
Hematopoietic Cell Lineage Pathway antibodies	Hematopoietic Cell Lineage Pathway Diagram
Hematopoietic Cell Lineage Pathway antibodies	Hematopoietic Cell Lineage Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Jak-STAT Signaling Pathway antibodies	Jak-STAT Signaling Pathway Diagram
Jak-STAT Signaling Pathway antibodies	Jak-STAT Signaling Pathway Diagram
Malaria Pathway antibodies	Malaria Pathway Diagram

Diseases associated with anti-G-CSF antibody

Disease Name	Pubmed Publications
Disease Susceptibility Antibodies	>7 publications with G-CSF and Disease Susceptibility
Nervous System Diseases Antibodies	>7 publications with G-CSF and Nervous System Diseases
Neutropenia Antibodies	>5 publications with G-CSF and Neutropenia
Leukopenia Antibodies	>3 publications with G-CSF and Leukopenia
Breast Neoplasms Antibodies	>3 publications with G-CSF and Breast Neoplasms
Leukemia, Myeloid, Acute Antibodies	>3 publications with G-CSF and Leukemia, Myeloid, Acute
Neoplasm Metastasis Antibodies	>3 publications with G-CSF and Neoplasm Metastasis
Brain Injuries Antibodies	>2 publications with G-CSF and Brain Injuries
Anemia Antibodies	>2 publications with G-CSF and Anemia
Hypertrophy Antibodies	>2 publications with G-CSF and Hypertrophy

Organs/Tissues associated with anti-G-CSF antibody

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>10 publications with G-CSF and Lung
Mammary Gland Antibodies	>3 publications with G-CSF and Mammary Gland