• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Syntaxin 1a (STX1A) Antibody – Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS177715

Description: Rabbit IgG polyclonal antibody for Syntaxin-1A(STX1A) detection. Tested with WB in Human;Mouse;Rat.Background: Syntaxin-1A is a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of… More details

$210 / 0.01 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Syntaxin 1a (STX1A), Polyclonal Antibody
Full Product Name
Anti-Syntaxin 1a Antibody
Product Gene Name
Product Synonym Names
Syntaxin-1A; EPIM; Epimorphin; EPM; FP17469; HPC 1; Neuron specific antigen HPC 1; Neuron specific antigen HPC1; neuron-specific antigen HPC 1; P35 1; P35 1; STX 1; STX 1A; STX1; STX1; STX1A; Stx1b; STX1B_HUMAN; STX1B1; STX1B2; STX2; STX2A; STX2B; STX2C; STX3; STX3A; Syntaxin 1A; Syntaxin 1A brain; Syntaxin 1B; Syntaxin 1B1; Syntaxin 1B2; Syntaxin 2; Syntaxin 3; Syntaxin 3A; Syntaxin-1B; Syntaxin-1B1; Syntaxin-1B2; syntaxin 1A (brain)
Clonality
Polyclonal
Species Reactivity
Human, Mouse, Rat
Form/Format
Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Purity/Purification
Immunogen Affinity Purified
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquoted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Molecular Weight
28,995 Da
OMIM
186590
3D Structure
ModBase 3D Structure for Q16623
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human Syntaxin 1a(1-28aa MKDRTQELRTAKDSDDDDDVAVTVDRDR), different from the related mouse and rat sequences by one amino acid.
Ig Type
Rabbit IgG
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-STX1A antibody
Western Blot (WB)
Application Notes for anti-STX1A antibody
Western Blot Concentration: 0.1-0.5ug/ml

Western Blot (WB) of anti-STX1A antibody

Anti- Syntaxin 1a Picoband antibody, MBS177715, Western blotting
All lanes: Anti Syntaxin 1a (MBS177715) at 0.5ug/ml
Lane 1: Rat Brain Tissue Lysate at 50ug
Lane 2: Mouse Brain Tissue Lysate at 50ug
Lane 3: U87 Whole Cell Lysate at 40ug
Predicted bind size: 33KD
Observed bind size: 37KD
Anti-STX1A Polyclonal Antibody – Cat# MBS177715

Product References and Citations for anti-STX1A antibody

1. "Entrez Gene: STX1A syntaxin 1A (brain)". 2. Bennett MK, García-Arrarás JE, Elferink LA, Peterson K, Fleming AM, Hazuka CD, Scheller RH (September 1993). "The syntaxin family of vesicular transport receptors".Cell 74 (5): 863-73.

Other Notes

Small volumes of anti-STX1A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for STX1A purchase

MBS177715 is an antibody targeting STX1A. Also known as Anti-Syntaxin 1a Antibody. Reactive in Human, Mouse, Rat.

Additional Details

NCBI/Uniprot data below describe general gene information for STX1A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
syntaxin-1A isoform 2
NCBI Official Synonym Full Names
syntaxin 1A
NCBI Official Symbol
STX1A
NCBI Official Synonym Symbols
STX1; HPC-1; P35-1; SYN1A
UniProt Protein Name
Syntaxin-1A
UniProt Synonym Protein Names
Neuron-specific antigen HPC-1
Protein Family
UniProt Gene Name
STX1A
UniProt Synonym Gene Names
STX1
UniProt Entry Name
STX1A_HUMAN
NCBI Protein Information
syntaxin-1A

NCBI Summary for STX1A

This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
Show more

UniProt Comments for STX1A

Plays a role in hormone and neurotransmitter exocytosis (). Potentially involved in docking of synaptic vesicles at presynaptic active zones. May mediate Ca2+-regulation of exocytosis acrosomal reaction in sperm.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000