Anti-IL7 Polyclonal Antibody – Cat# MBS177787

Western blot analysis of IL7 expression in mouse brain extract (lane 1), mouse thymus extract (lane 2) and NIH3T3 whole cell lysates (lane 3). IL7 at 20KD was detected using rabbit anti- IL7 Antigen Affinity purified polyclonal antibody at0.5 ug/mL. The blot was developed using chemiluminescence (ECL) method.

IL7 Antibody – Polyclonal

Name: IL7 Antibody; Polyclonal; Mouse-Reactive; Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS177787
Price: 210 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS177787

Description: Rabbit IgG polyclonal antibody for Interleukin-7(IL7) detection. Tested with WB in Mouse.Background: Interleukin 7 (IL-7) is a protein that in humans is encoded by the IL7 gene. The protein encoded by this gene is a cytokine important for B… More details

$210 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

IL7, Polyclonal Antibody

Full Product Name

Anti-IL7 Antibody

Product Gene Name

anti-IL7 antibody

Product Synonym Names

Interleukin-7; IL 7; IL-7; Il7; Interleukin 7; Interleukin-7; interleukin 7

Clonality

Polyclonal

Species Reactivity

Mouse

Form/Format

Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purity/Purification

Immunogen Affinity Purified

Preparation and Storage

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquoted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

Molecular Weight

17,727 Da

3D Structure

ModBase 3D Structure for P10168

Immunogen

E Coli-derived mouse IL7 recombinant protein (Position: E26-I154). Mouse IL7 shares 56.4% and 87.6% amino acid (aa) sequence identity with human and rat IL7, respectively.

Ig Type

Rabbit IgG

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Applications Tested/Suitable for anti-IL7 antibody

Western Blot (WB)

Application Notes for anti-IL7 antibody

Western Blot Concentration: 0.1-0.5ug/ml

Product References and Citations for anti-IL7 antibody

1. Goodwin RG, Lupton S, Schmierer A, Hjerrild KJ, Jerzy R, Clevenger W, Gillis S, Cosman D, Namen AE (January 1989). "Human interleukin 7: molecular cloning and growth factor activity on human and murine B-lineage cells". Proc. Natl. Acad. Sci. U.S.A. 86 (1): 302-6. 2. Lupton SD, Gimpel S, Jerzy R, et al. (1990). "Characterization of the human and murine IL-7 genes". J. Immunol. 144 (9): 3592-601. 3. Sutherland GR, Baker E, Fernandez KE, Callen DF, Goodwin RG, Lupton S, Namen AE, Shannon MF, Vadas MA (July 1989). "The gene for human interleukin 7 (IL7) is at 8q12-13". Hum. Genet. 82 (4): 371-2.

Other Notes

Small volumes of anti-IL7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL7 purchase

MBS177787 is an antibody targeting IL7. Reactive in Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for IL7. It may not necessarily be applicable to this product.

NCBI GI #

6680433

NCBI GeneID

16196

NCBI Accession #

NP_032397.1

UniProt Primary Accession #

P10168

UniProt Related Accession #

P10168

GenBank Nucleotide #

NM_008371.5

NCBI Official Full Name

interleukin-7 isoform a

NCBI Official Synonym Full Names

interleukin 7

NCBI Official Symbol

Il7

NCBI Official Synonym Symbols

Il-7; hlb368; A630026I06Rik

UniProt Protein Name

Interleukin-7

Protein Family

Interleukin

UniProt Gene Name

Il7

UniProt Synonym Gene Names

Il-7; IL-7

UniProt Entry Name

IL7_MOUSE

NCBI Protein Information

interleukin-7

NCBI Summary for IL7

The protein encoded by this gene is a hematopoietic growth factor important for B and T cell development. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]

UniProt Comments for IL7

IL7: Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Cell cycle regulation; Cytokine; Cell development/differentiation; Apoptosis; Secreted

Cellular Component: extracellular region; extracellular space

Molecular Function: cytokine activity; growth factor activity; hematopoietin/interferon-class (D200-domain) cytokine receptor binding; interleukin-7 receptor binding

Biological Process: bone resorption; cell-cell signaling; homeostasis of number of cells within a tissue; humoral immune response; immune response; negative regulation of catalytic activity; organ morphogenesis; positive regulation of B cell proliferation; positive regulation of organ growth; positive regulation of T cell differentiation; regulation of gene expression; T cell lineage commitment

Research Articles on IL7

1. This study uncovers the metabolic mechanisms by which IL-7 tailors the metabolism of memory T cells to promote their longevity and fast response to rechallenge.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-IL7 antibody

Products by Pathway	Pathway Diagram
Cytokine Signaling In Immune System Pathway antibodies	Cytokine Signaling In Immune System Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokines And Inflammatory Response (BioCarta) Pathway antibodies	Cytokines And Inflammatory Response (BioCarta) Pathway Diagram
Hematopoietic Cell Lineage Pathway antibodies	Hematopoietic Cell Lineage Pathway Diagram
Hematopoietic Cell Lineage Pathway antibodies	Hematopoietic Cell Lineage Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Interleukin-7 Signaling Pathway antibodies	Interleukin-7 Signaling Pathway Diagram
Jak-STAT Signaling Pathway antibodies	Jak-STAT Signaling Pathway Diagram
Jak-STAT Signaling Pathway antibodies	Jak-STAT Signaling Pathway Diagram

Diseases associated with anti-IL7 antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>39 publications with IL7 and Inflammation
Necrosis Antibodies	>27 publications with IL7 and Necrosis
Nervous System Diseases Antibodies	>23 publications with IL7 and Nervous System Diseases
Multiple Sclerosis Antibodies	>23 publications with IL7 and Multiple Sclerosis
Lymphopenia Antibodies	>22 publications with IL7 and Lymphopenia
Neoplasms, Experimental Antibodies	>12 publications with IL7 and Neoplasms, Experimental
Lung Diseases Antibodies	>9 publications with IL7 and Lung Diseases
Hypersensitivity Antibodies	>7 publications with IL7 and Hypersensitivity
Cell Transformation, Neoplastic Antibodies	>7 publications with IL7 and Cell Transformation, Neoplastic
Breast Neoplasms Antibodies	>6 publications with IL7 and Breast Neoplasms

Organs/Tissues associated with anti-IL7 antibody

Organ/Tissue Name	Pubmed Publications
Other Antibodies	>57 publications with IL7 and Other
Thymus Antibodies	>46 publications with IL7 and Thymus
Liver Antibodies	>15 publications with IL7 and Liver
Lung Antibodies	>12 publications with IL7 and Lung
Spleen Antibodies	>12 publications with IL7 and Spleen
Embryonic Tissue Antibodies	>5 publications with IL7 and Embryonic Tissue
Ovary Antibodies	>3 publications with IL7 and Ovary
Mammary Gland Antibodies	>3 publications with IL7 and Mammary Gland