• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

MNAT1 Antibody – Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS177855

Description: Rabbit IgG polyclonal antibody for CDK-activating kinase assembly factor MAT1(MNAT1) detection. Tested with WB, IHC-P in Human;Mouse;Rat. Background: CDK-activating kinase assembly factor MAT1 is an enzyme that in humans is encoded by the MNAT1… More details

$210 / 0.01 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MNAT1, Polyclonal Antibody
Full Product Name
Anti-MNAT1 Antibody
Product Gene Name
Product Synonym Names
CDK-activating kinase assembly factor MAT1; MNAT 1; MNAT 1; CAP35; CDK activating kinase assembly factor MAT1; CDK-activating kinase assembly factor MAT1; CDK7/cyclin H assembly factor; CDK7/cyclin-H assembly factor; Cyclin G1 interacting protein; Cyclin-G1-interacting protein; MAT1; MAT1_HUMAN; Menage a trois 1 (CAK assembly factor); Menage a trois; Menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis); MNAT CDK activating kinase assembly factor 1; Mnat1; p35; p36; RING finger protein 66; RING finger protein MAT1; RNF66; TFB3; MNAT CDK-activating kinase assembly factor 1
Clonality
Polyclonal
Species Reactivity
Human, Mouse, Rat
Form/Format
Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Purity/Purification
Immunogen Affinity Purified
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquoted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Molecular Weight
31,148 Da
OMIM
602659
3D Structure
ModBase 3D Structure for P51948
Immunogen
E Coli-derived human MNAT1 recombinant protein (Position: L92-A278). Human MNAT1 shares 93% amino acid (aa) sequence identity with mouse MNAT1.
Ig Type
Rabbit IgG
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-MNAT1 antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin
Application Notes for anti-MNAT1 antibody
Western Blot Concentration: 0.1-0.5ug/ml
Immunohistochemistry (IHC) Paraffin Concentration: 0.5-1ug/ml

Western Blot (WB) of anti-MNAT1 antibody

Anti- MNAT1 Picoband antibody, MBS177855, Western blotting
All lanes: Anti MNAT1 (MBS177855) at 0.5ug/ml
Lane 1: Rat Brain Tissue Lysate at 50ug
Lane 2: Rat Liver Tissue Lysate at 50ug
Lane 3: MCF-7 Whole Cell Lysate at 40ug
Lane 4: HELA Whole Cell Lysate at 40ug
Predicted bind size: 81KD
Observed bind size: 81KD
Anti-MNAT1 Polyclonal Antibody – Cat# MBS177855

Immunohistochemistry (IHC) of anti-MNAT1 antibody

Anti- MNAT1 Picoband antibody, MBS177855, IHC(P)
IHC(P): Mouse Testis Tissue
Anti-MNAT1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS177855

Immunohistochemistry (IHC) of anti-MNAT1 antibody

Anti- MNAT1 Picoband antibody, MBS177855, IHC(P)
IHC(P): Rat Testis Tissue
Anti-MNAT1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS177855

Immunohistochemistry (IHC) of anti-MNAT1 antibody

Anti- MNAT1 Picoband antibody, MBS177855, IHC(P)
IHC(P): Human Testis Tissue
Anti-MNAT1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS177855

Product References and Citations for anti-MNAT1 antibody

1. "Entrez Gene: MNAT1 menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis)". 2. Eki T, Okumura K, Abe M, Kagotani K, Taguchi H, Murakami Y, Pan ZQ, Hanaoka F (April 1998). "Mapping of the human genes encoding cyclin H (CCNH) and the CDK-activating kinase (CAK) assembly factor MAT1 (MNAT1) to chromosome bands 5q13.3-q14 and 14q23, respectively". Genomics 47 (1): 115-20. 3. Talukder AH, Mishra SK, Mandal M, Balasenthil S, Mehta S, Sahin AA, Barnes CJ, Kumar R (March 2003). "MTA1 interacts with MAT1, a cyclin-dependent kinase-activating kinase complex ring finger factor, and regulates estrogen receptor transactivation functions". J. Biol. Chem. 278 (13): 11676-85.

Other Notes

Small volumes of anti-MNAT1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MNAT1 purchase

MBS177855 is an antibody targeting MNAT1. Reactive in Human, Mouse, Rat.

Additional Details

NCBI/Uniprot data below describe general gene information for MNAT1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
CDK-activating kinase assembly factor MAT1 isoform 2
NCBI Official Synonym Full Names
MNAT1, CDK activating kinase assembly factor
NCBI Official Symbol
MNAT1
NCBI Official Synonym Symbols
MAT1; TFB3; CAP35; RNF66
UniProt Protein Name
CDK-activating kinase assembly factor MAT1
UniProt Synonym Protein Names
CDK7/cyclin-H assembly factor; Cyclin-G1-interacting protein; Menage a trois; RING finger protein 66; RING finger protein MAT1; p35; p36
UniProt Gene Name
MNAT1
UniProt Synonym Gene Names
CAP35; MAT1; RNF66
UniProt Entry Name
MAT1_HUMAN
NCBI Protein Information
CDK-activating kinase assembly factor MAT1

NCBI Summary for MNAT1

The protein encoded by this gene, along with cyclin H and CDK7, forms the CDK-activating kinase (CAK) enzymatic complex. This complex activates several cyclin-associated kinases and can also associate with TFIIH to activate transcription by RNA polymerase II. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Show more

UniProt Comments for MNAT1

Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II.
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000