• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

KCND1 Antibody – Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS178020

Description: Rabbit IgG polyclonal antibody for Potassium voltage-gated channel subfamily D member 1(KCND1) detection. Tested with WB in Human;Mouse.Background: Potassium voltage-gated channel, Shal-related subfamily, member 1 (KCND1), also known as Kv4.1, is… More details

$210 / 0.01 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
KCND1, Polyclonal Antibody
Full Product Name
Anti-KCND1 Antibody
Product Gene Name
anti-KCND1 antibody
Product Synonym Names
Potassium voltage-gated channel subfamily D member 1; Kcnd1; KCND1_HUMAN; Kv4.1; mShal; OTTHUMP00000025805; OTTHUMP00000025806; Potassium voltage gated channel Shal related subfamily member 1; Potassium voltage gated channel subfamily D member 1; Potassium voltage-gated channel subfamily D member 1; Shal type potassium channel; Voltage gated potassium channel Kv4.1; Voltage gated potassium channel subunit Kv4.1; Voltage-gated potassium channel subunit Kv4.1; potassium voltage-gated channel, Shal-related subfamily, member 1
Clonality
Polyclonal
Species Reactivity
Human, Mouse
Form/Format
Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Purity/Purification
Immunogen Affinity Purified
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquoted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Molecular Weight
28,860 Da
OMIM
300281
3D Structure
ModBase 3D Structure for Q9NSA2
Immunogen
E Coli-derived human KCND1 recombinant protein (Position: T442-L647). Human KCND1 shares 90% amino acid (aa) sequence identity with mouse KCND1.
Ig Type
Rabbit IgG
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-KCND1 antibody
Western Blot (WB)
Application Notes for anti-KCND1 antibody
Western Blot Concentration: 0.1-0.5ug/ml

Western Blot (WB) of anti-KCND1 antibody

Anti- KCND1 Picoband antibody, MBS178020, Western blotting
All lanes: Anti KCND1 (MBS178020) at 0.5ug/ml
WB: Recombinant Human KCND1 Protein 0.5ng
Predicted bind size: 39KD
Observed bind size: 39KD
Anti-KCND1 Polyclonal Antibody – Cat# MBS178020

Western Blot (WB) of anti-KCND1 antibody

Anti- KCND1 Picoband antibody, MBS178020, Western blotting
All lanes: Anti KCND1 (MBS178020) at 0.5ug/ml
Lane 1: Mouse Brain Tissue Lysate at 50ug
Lane 2: HELA Whole Cell Lysate at 40ug
Lane 3: COLO320 Whole Cell Lysate at 40ug
Lane 4: A549 Whole Cell Lysate at 40ug
Predicted bind size: 71KD
Observed bind size: 71KD
Anti-KCND1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS178020

Product References and Citations for anti-KCND1 antibody

1. "Entrez Gene: KCND1 potassium voltage-gated channel, Shal-related subfamily, member 1" 2. Isbrandt, D., Leicher, T., Waldschutz, R., Zhu, X., Luhmann, U., Michel, U., Sauter, K., Pongs, O. Gene structures and expression profiles of three human KCND (Kv4) potassium channels mediating A-type currents I(to) and I(sa). Genomics 64: 144-154, 2000.

Other Notes

Small volumes of anti-KCND1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KCND1 purchase

MBS178020 is an antibody targeting KCND1. Reactive in Human, Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for KCND1. It may not necessarily be applicable to this product.

NCBI GI #
27436981
NCBI GeneID
3750
NCBI Accession #
NP_004970.3
UniProt Primary Accession #
Q9NSA2
UniProt Secondary Accession #
O75671; A6NEF1; B2RCG0
UniProt Related Accession #
Q9NSA2
GenBank Nucleotide #
NM_004979.5
NCBI Official Full Name
potassium voltage-gated channel subfamily D member 1
NCBI Official Synonym Full Names
potassium voltage-gated channel subfamily D member 1
NCBI Official Symbol
KCND1
NCBI Official Synonym Symbols
KV4.1
UniProt Protein Name
Potassium voltage-gated channel subfamily D member 1
UniProt Synonym Protein Names
Voltage-gated potassium channel subunit Kv4.1
Protein Family
Potassium voltage-gated channel subfamily
UniProt Gene Name
KCND1
UniProt Entry Name
KCND1_HUMAN
NCBI Protein Information
potassium voltage-gated channel subfamily D member 1

NCBI Summary for KCND1

This gene encodes a multipass membrane protein that comprises the pore subunit of the voltage-gated A-type potassium channel, which functions in the repolarization of membrane action potentials. Activity of voltage-gated potassium channels is important in a number of physiological processes, among them the regulation of neurotransmitter release, heart rate, insulin secretion, and smooth muscle contraction. [provided by RefSeq, Aug 2013]
Show more

UniProt Comments for KCND1

KCND1: Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits. Belongs to the potassium channel family. D (Shal) (TC 1.A.1.2) subfamily. Kv4.1/KCND1 sub-subfamily.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: Xp11.23

Cellular Component: cell soma; dendrite; integral to membrane; plasma membrane; voltage-gated potassium channel complex

Molecular Function: A-type (transient outward) potassium channel activity; delayed rectifier potassium channel activity; metal ion binding

Biological Process: protein homooligomerization
Show more

Research Articles on KCND1

1. S-glutathionylation of an auxiliary subunit confers redox sensitivity to Kv4 channel inactivation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-KCND1 antibody

 Products by Pathway  Pathway Diagram
 Cardiac Conduction Pathway antibodies  Cardiac Conduction Pathway Diagram
 Muscle Contraction Pathway antibodies  Muscle Contraction Pathway Diagram
 Neuronal System Pathway antibodies  Neuronal System Pathway Diagram
 Phase 1 - Inactivation Of Fast Na+ Channels Pathway antibodies  Phase 1 - Inactivation Of Fast Na+ Channels Pathway Diagram
 Potassium Channels Pathway antibodies  Potassium Channels Pathway Diagram
 Voltage Gated Potassium Channels Pathway antibodies  Voltage Gated Potassium Channels Pathway Diagram

Diseases associated with anti-KCND1 antibody

 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >1 publications with KCND1 and Disease Models, Animal
 Infertility, Male Antibodies  >1 publications with KCND1 and Infertility, Male

Organs/Tissues associated with anti-KCND1 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >10 publications with KCND1 and Brain
 Heart Antibodies  >4 publications with KCND1 and Heart
 Intestine Antibodies  >1 publications with KCND1 and Intestine
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000