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PTOV1 Antibody – Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS178055

Description: Rabbit IgG polyclonal antibody for Prostate tumor-overexpressed gene 1 protein(PTOV1) detection. Tested with WB in Human;Rat.Background: Prostate tumor overexpressed gene 1 protein is a protein that in humans is encoded by the PTOV1 gene. It is… More details

$210 / 0.01 mg +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
PTOV1, Polyclonal Antibody
Full Product Name
Anti-PTOV1 Antibody
Product Gene Name
Product Synonym Names
Prostate tumor-overexpressed gene 1 protein; ACID2; Activator interaction domain containing protein 2; Gcap3; prostate tumor overexpressed 1; Prostate tumor overexpressed gene 1; PTOV 1; prostate tumor overexpressed 1
Clonality
Polyclonal
Species Reactivity
Rat
Predicted to work with: Human
Form/Format
Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Purity/Purification
Immunogen Affinity Purified
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquoted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Molecular Weight
26,145 Da
OMIM
610195
3D Structure
ModBase 3D Structure for Q86YD1
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human PTOV1 (385-414aa NFVNGIRRVIANQQQVLQRNLEQEQQQRGM), different from the related mouse and rat sequences by one amino acid.
Ig Type
Rabbit IgG
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-PTOV1 antibody
Western Blot (WB)
Application Notes for anti-PTOV1 antibody
Western Blot Concentration: 0.1-0.5ug/ml

Western Blot (WB) of anti-PTOV1 antibody

Anti- PTOV1 antibody, Western blotting
All lanes: Anti PTOV1 at 0.5ug/ml
Anti-PTOV1 Polyclonal Antibody – Cat# MBS178055

Product References and Citations for anti-PTOV1 antibody

1. "Entrez Gene: PTOV1 prostate tumor overexpressed gene 1". 2. Santamaria A, Castellanos E, Gomez V, Benedit P, Renau-Piqueras J, Morote J, Reventos J, Thomson TM, Paciucci R (Feb 2005). "PTOV1 enables the nuclear translocation and mitogenic activity of flotillin-1, a major protein of lipid rafts". Mol Cell Biol 25 (5): 1900-11. 3. Santamaria A, Fernandez PL, Farre X, Benedit P, Reventos J, Morote J, Paciucci R, Thomson TM (Feb 2003)."PTOV-1, a novel protein overexpressed in prostate cancer, shuttles between the cytoplasm and the nucleus and promotes entry into the S phase of the cell division cycle". Am J Pathol 162 (3): 897-905.

Other Notes

Small volumes of anti-PTOV1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PTOV1 purchase

MBS178055 is an antibody targeting PTOV1. Reactive in Rat
Predicted to work with: Human.

Additional Details

NCBI/Uniprot data below describe general gene information for PTOV1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
prostate tumor-overexpressed gene 1 protein isoform 1
NCBI Official Synonym Full Names
prostate tumor overexpressed 1
NCBI Official Symbol
PTOV1
NCBI Official Synonym Symbols
ACID2; PTOV-1
UniProt Protein Name
Prostate tumor-overexpressed gene 1 protein
UniProt Synonym Protein Names
Activator interaction domain-containing protein 2
UniProt Gene Name
PTOV1
UniProt Synonym Gene Names
ACID2; PTOV-1
UniProt Entry Name
PTOV1_HUMAN
NCBI Protein Information
prostate tumor-overexpressed gene 1 protein

NCBI Summary for PTOV1

This gene encodes a protein that was found to be overexpressed in prostate adenocarcinomas. The encoded protein was found to interact with the lipid raft protein flotillin-1 and shuttle it from the cytoplasm to the nucleus in a cell cycle dependent manner. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2015]
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UniProt Comments for PTOV1

PTOV1: May activate transcription. Required for nuclear translocation of FLOT1. Promotes cell proliferation. Belongs to the Mediator complex subunit 25 family. PTOV1 subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 19q13.33

Cellular Component: nucleus; perinuclear region of cytoplasm; plasma membrane

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PTOV1 antibody

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