Anti-BCHE Polyclonal Antibody – Cat# MBS178090

Anti- BCHE Picoband antibody, MBS178090, Western blotting
All lanes: Anti BCHE (MBS178090) at 0.5ug/ml
WB: HEPA Whole Cell Lysate at 40ug
Predicted bind size: 66KD
Observed bind size: 66KD

BCHE Antibody – Polyclonal

Name: BCHE Antibody; Polyclonal; Mouse-Reactive; Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS178090
Price: 210 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS178090

Description: Rabbit IgG polyclonal antibody for Cholinesterase(BCHE) detection. Tested with WB in Mouse.Background: Butyrylcholinesterase (BCHE, or BuChE), also known as pseudocholinesterase or plasma cholinesterase, is a non-specific cholinesterase enzyme… More details

$210 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

BCHE, Polyclonal Antibody

Full Product Name

Anti-BCHE Antibody

Product Gene Name

anti-BCHE antibody

Product Synonym Names

Cholinesterase; Acylcholine acylhydrolase; BCHE; Butyrylcholine esterase; CHE1; CHE2; CHLE_HUMAN; Choline esterase II; Cholinesterase (serum) 2; Cholinesterase 1; Cholinesterase; E1; Pseudocholinesterase; butyrylcholinesterase

Clonality

Polyclonal

Species Reactivity

Mouse

Form/Format

Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purity/Purification

Immunogen Affinity Purified

Specificity

No cross reactivity with other proteins

Preparation and Storage

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquoted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

3D Structure

ModBase 3D Structure for Q03311

Immunogen

E Coli-derived mouse BCHE recombinant protein (Position: K263-E571). Mouse BCHE shares 78% amino acid (aa) sequence identity with human BCHE.

Ig Type

Rabbit IgG

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Applications Tested/Suitable for anti-BCHE antibody

Western Blot (WB)

Application Notes for anti-BCHE antibody

WB :
Concentration : 0.1-0.5ug/ml
Tested Species : Mouse

Tested Species : In house tested species with positive results.
Other applications have not been tested.
Optimal dilutions should be determined by end users.

Product References and Citations for anti-BCHE antibody

1. Allderdice PW, Gardner HA, Galutira D, Lockridge O, LaDu BN, McAlpine PJ (Oct 1991). "The cloned butyrylcholinesterase (BCHE) gene maps to a single chromosome site, 3q26". Genomics 11 (2): 452-4. 2. Jasmin L (2013-05-28). "Cholinesterase - blood". University of Maryland Medical Center. 3. Pohanka M (2013). "Butyrylcholinesterase as a biochemical marker". Bratislavské Lekárske Listy 114 (12): 726-734.

Other Notes

Small volumes of anti-BCHE antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BCHE purchase

MBS178090 is an antibody targeting BCHE. Reactive in Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for BCHE. It may not necessarily be applicable to this product.

NCBI GI #

124487350

NCBI GeneID

12038

NCBI Accession #

NP_033868.3

UniProt Primary Accession #

Q03311

UniProt Secondary Accession #

Q543J3

UniProt Related Accession #

Q03311

GenBank Nucleotide #

NM_009738.3

NCBI Official Full Name

cholinesterase

NCBI Official Synonym Full Names

butyrylcholinesterase

NCBI Official Symbol

Bche

NCBI Official Synonym Symbols

C730038G20Rik

UniProt Protein Name

Cholinesterase

UniProt Synonym Protein Names

Acylcholine acylhydrolase; Butyrylcholine esterase; Choline esterase II; Pseudocholinesterase

Protein Family

Anaerobic magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase

UniProt Gene Name

Bche

UniProt Entry Name

CHLE_MOUSE

NCBI Protein Information

cholinesterase

UniProt Comments for BCHE

BCHE: Esterase with broad substrate specificity. Contributes to the inactivation of the neurotransmitter acetylcholine. Can degrade neurotoxic organophosphate esters. Defects in BCHE are the cause of butyrylcholinesterase deficiency (BChE deficiency). BChE deficiency is a metabolic disorder characterized by prolonged apnoea after the use of certain anesthetic drugs, including the muscle relaxants succinylcholine or mivacurium and other ester local anesthetics. The duration of the prolonged apnoea varies significantly depending on the extent of the enzyme deficiency. BChE deficiency is a multifactorial disorder. The hereditary condition is transmitted as an autosomal recessive trait. Belongs to the type-B carboxylesterase/lipase family.

Protein type: Hydrolase; Nuclear envelope; Secreted; EC 3.1.1.8; Secreted, signal peptide

Cellular Component: endoplasmic reticulum; endoplasmic reticulum lumen; extracellular region; extracellular space; membrane; nuclear envelope lumen

Molecular Function: 1-oxa-2-oxocycloheptane lactonase activity; 3,4-dihydrocoumarin hydrolase activity; acetylcholinesterase activity; all-trans-retinyl-palmitate hydrolase activity; butyrolactone hydrolase activity; choline binding; cholinesterase activity; hydrolase activity; identical protein binding; lipase activity; phospholipase activity; prenylcysteine methylesterase activity; retinyl-palmitate esterase activity; sulfolactone hydrolase activity

Biological Process: choline metabolic process; learning; negative regulation of cell proliferation; negative regulation of synaptic transmission; neuroblast differentiation; response to alkaloid; response to drug; response to folic acid; response to glucocorticoid stimulus; response to nutrient

Research Articles on BCHE

1. Mice that had undergone gene transfer with mouse CocH (mCocH) showed no place preference or aversion after repeated treatments with a near-lethal 80 mg/kg cocaine dose.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-BCHE antibody

Reference Product	PubMed Publications
Colq antibody	>17 publications with BCHE and Colq
Iapp antibody	>1 publications with BCHE and Iapp
Ghrl antibody	>1 publications with BCHE and Ghrl

Pathways associated with anti-BCHE antibody

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Diseases associated with anti-BCHE antibody

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>3731 publications with BCHE and Nervous System Diseases
Poisoning Antibodies	>1944 publications with BCHE and Poisoning
Alzheimer Disease Antibodies	>1250 publications with BCHE and Alzheimer Disease
Organophosphate Poisoning Antibodies	>735 publications with BCHE and Organophosphate Poisoning
Death Antibodies	>600 publications with BCHE and Death
Memory Disorders Antibodies	>428 publications with BCHE and Memory Disorders
Neurobehavioral Manifestations Antibodies	>399 publications with BCHE and Neurobehavioral Manifestations
Apnea Antibodies	>364 publications with BCHE and Apnea
Nerve Degeneration Antibodies	>359 publications with BCHE and Nerve Degeneration
Learning Disorders Antibodies	>323 publications with BCHE and Learning Disorders

Organs/Tissues associated with anti-BCHE antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>9057 publications with BCHE and Brain
Muscle Antibodies	>4088 publications with BCHE and Muscle
Liver Antibodies	>2194 publications with BCHE and Liver
Heart Antibodies	>978 publications with BCHE and Heart
Eye Antibodies	>717 publications with BCHE and Eye
Spinal Cord Antibodies	>674 publications with BCHE and Spinal Cord
Embryonic Tissue Antibodies	>664 publications with BCHE and Embryonic Tissue
Lung Antibodies	>335 publications with BCHE and Lung
Pancreas Antibodies	>167 publications with BCHE and Pancreas
Bladder Antibodies	>133 publications with BCHE and Bladder