Anti-WNT2 Polyclonal Antibody – Cat# MBS178216

Anti-WNT2 Picoband antibody, MBS178216, Western blotting
All lanes: Anti WNT2 (MBS178216) at 0.5ug/ml
Lane 1: COLO320 Whole Cell Lysate at 40ug
Lane 2: MCF-7 Whole Cell Lysate at 40ug
Lane 3: HELA Whole Cell Lysate at 40ug
Predicted bind size: 40KD
Observed bind size: 40KD

WNT2 Antibody – Polyclonal

Name: WNT2 Antibody; Polyclonal; Human-Reactive; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS178216
Price: 210 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS178216

Description: Rabbit IgG polyclonal antibody for Protein Wnt-2(WNT2) detection. Tested with WB in Human.Background: WNT2, also known as Wingless-type MMTV integration site family, member 2, is a human gene. This gene is a member of the WNT gene family. The WNT… More details

$210 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Wnt2, Polyclonal Antibody

Full Product Name

Anti-Wnt2 Antibody

Product Gene Name

anti-WNT2 antibody

Product Synonym Names

Protein Wnt-2; Int 1 related protein; Int 1 related protein; Int-1-like protein 1; Int-1-related protein; INT1L 1; INT1L1; IRP; IRP protein; IRP protein; ONCOGENE INT1 LIKE 1; Protein Wnt-2; Secreted growth factor; Wingless type MMTV integration site family member 2; WNT 2; WNT 2; WNT2; WNT2_HUMAN; wingless-type MMTV integration site family member 2

Clonality

Polyclonal

Species Reactivity

Human

Form/Format

Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purity/Purification

Immunogen Affinity Purified

Preparation and Storage

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquoted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

Molecular Weight

40,418 Da

OMIM

147870

3D Structure

ModBase 3D Structure for P09544

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human Wnt2 (56-81aa HRHPDVMRAISQGVAEWTAECQHQFR), different from the related mouse sequence by two amino acids.

Ig Type

Rabbit IgG

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Applications Tested/Suitable for anti-WNT2 antibody

Western Blot (WB)

Application Notes for anti-WNT2 antibody

Western Blot Concentration: 0.1-0.5ug/ml

Product References and Citations for anti-WNT2 antibody

1. "Entrez Gene: WNT2 wingless-type MMTV integration site family, member 2" 2. Wainwright BJ, Scambler PJ, Stanier P, Watson EK, Bell G, Wicking C, Estivill X, Courtney M, Boue A, Pedersen PS (June 1988). "Isolation of a human gene with protein sequence similarity to human and murine int-1 and the Drosophila segment polarity mutant wingless". EMBO J. 7(6): 1743-8.

Other Notes

Small volumes of anti-WNT2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for WNT2 purchase

MBS178216 is an antibody targeting WNT2. Reactive in Human.

Additional Details

NCBI/Uniprot data below describe general gene information for WNT2. It may not necessarily be applicable to this product.

NCBI GI #

4507927

NCBI GeneID

7472

NCBI Accession #

NP_003382.1

UniProt Primary Accession #

P09544

UniProt Secondary Accession #

Q75N05; Q9UDP9; A4D0V1

UniProt Related Accession #

P09544

GenBank Nucleotide #

NM_003391.2

NCBI Official Full Name

protein Wnt-2

NCBI Official Synonym Full Names

Wnt family member 2

NCBI Official Symbol

WNT2

NCBI Official Synonym Symbols

IRP; INT1L1

UniProt Protein Name

Protein Wnt-2

UniProt Synonym Protein Names

Int-1-like protein 1; Int-1-related protein; IRP

UniProt Gene Name

WNT2

UniProt Synonym Gene Names

INT1L1; IRP; IRP

UniProt Entry Name

WNT2_HUMAN

NCBI Protein Information

protein Wnt-2

NCBI Summary for WNT2

This gene is a member of the WNT gene family. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jul 2008]

UniProt Comments for WNT2

WNT2: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. Belongs to the Wnt family.

Protein type: Extracellular matrix; Secreted, signal peptide; Secreted; Cell development/differentiation; Cell adhesion

Chromosomal Location of Human Ortholog: 7q31.2

Cellular Component: cytoplasm; extracellular matrix; extracellular region; extracellular space; plasma membrane; proteinaceous extracellular matrix

Molecular Function: cytokine activity; frizzled binding; protein binding; receptor agonist activity

Biological Process: atrial cardiac muscle morphogenesis; cell fate commitment; cell proliferation in midbrain; cell-cell signaling; lens development in camera-type eye; lung development; neurogenesis; neuron differentiation; positive regulation of cardiac muscle cell proliferation; positive regulation of cell proliferation; positive regulation of endothelial cell proliferation; positive regulation of fibroblast proliferation; positive regulation of mesenchymal cell proliferation; positive regulation of neurogenesis; positive regulation of transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; Wnt receptor signaling pathway; Wnt receptor signaling pathway through beta-catenin

Research Articles on WNT2

1. Wnt2/beta-catenin signaling was involved in stromal-epithelial cells interaction in endometriosis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-WNT2 antibody

Products by Pathway	Pathway Diagram
Basal Cell Carcinoma Pathway antibodies	Basal Cell Carcinoma Pathway Diagram
Basal Cell Carcinoma Pathway antibodies	Basal Cell Carcinoma Pathway Diagram
Class B/2 (Secretin Family Receptors) Pathway antibodies	Class B/2 (Secretin Family Receptors) Pathway Diagram
DNA Damage Response (only ATM Dependent) Pathway antibodies	DNA Damage Response (only ATM Dependent) Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
HTLV-I Infection Pathway antibodies	HTLV-I Infection Pathway Diagram
HTLV-I Infection Pathway antibodies	HTLV-I Infection Pathway Diagram
Hedgehog Signaling Pathway antibodies	Hedgehog Signaling Pathway Diagram
Hedgehog Signaling Pathway antibodies	Hedgehog Signaling Pathway Diagram
Hippo Signaling Pathway antibodies	Hippo Signaling Pathway Diagram

Diseases associated with anti-WNT2 antibody

Disease Name	Pubmed Publications
Disease Models, Animal Antibodies	>21 publications with WNT2 and Disease Models, Animal
Breast Neoplasms Antibodies	>19 publications with WNT2 and Breast Neoplasms
Adenocarcinoma Antibodies	>19 publications with WNT2 and Adenocarcinoma
Fibrosis Antibodies	>15 publications with WNT2 and Fibrosis
Lung Diseases Antibodies	>13 publications with WNT2 and Lung Diseases
Cell Transformation, Neoplastic Antibodies	>13 publications with WNT2 and Cell Transformation, Neoplastic
Neoplasm Metastasis Antibodies	>12 publications with WNT2 and Neoplasm Metastasis
Autistic Disorder Antibodies	>12 publications with WNT2 and Autistic Disorder
Lung Neoplasms Antibodies	>11 publications with WNT2 and Lung Neoplasms
Neoplasm Invasiveness Antibodies	>6 publications with WNT2 and Neoplasm Invasiveness

Organs/Tissues associated with anti-WNT2 antibody

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>47 publications with WNT2 and Lung
Embryonic Tissue Antibodies	>41 publications with WNT2 and Embryonic Tissue
Brain Antibodies	>26 publications with WNT2 and Brain
Placenta Antibodies	>14 publications with WNT2 and Placenta
Intestine Antibodies	>13 publications with WNT2 and Intestine
Kidney Antibodies	>10 publications with WNT2 and Kidney
Uterus Antibodies	>9 publications with WNT2 and Uterus
Connective Tissue Antibodies	>7 publications with WNT2 and Connective Tissue
Prostate Antibodies	>6 publications with WNT2 and Prostate
Testis Antibodies	>6 publications with WNT2 and Testis