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SLC2A5 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS178460

Rabbit IgG polyclonal antibody for Solute carrier family 2, facilitated glucose transporter member 5 (SLC2A5) detection. Background: SLC2A5, also known as GLUT5 (Glucose transporter 5), is a fructose transporter expressed on the apical border of enterocytes… More details

$210 / 0.01 mg +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
SLC2A5, Polyclonal Antibody
Full Product Name
Anti-SLC2A5 Antibody
Product Gene Name
anti-SLC2A5 antibody
Product Synonym Names
Glucose Transporter 5; GLUT5; GLUT-5; GTR5; SLC 2A5; SLC2A5; P22732 ; Solute carrier family 2, facilitated glucose transporter member 5; solute carrier family 2 (facilitated glucose/fructose transporter), member 5
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Rat
No cross reactivity with other proteins.
Form/Format
Lyophilized
Purity/Purification
Immunogen affinity purified.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Molecular Weight
26,519 Da
OMIM
138230
3D Structure
ModBase 3D Structure for P22732
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human SLC2A5 (223-259aa QKKDEAAAKKALQTLRGWDSVDREVAEIRQEDEAEKA), different from the related mouse and rat sequences by nine amino acids.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-SLC2A5 antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin
Application Notes for anti-SLC2A5 antibody
Western Blot: 0.1-0.5mug/ml; Tested Species: Human, Rat
Immunohistochemisry Paraffin: 0.5-1mug/ml; Tested Species: Human, Rat
Tested Species:In-house tested species with positive results.
By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections.
Other applications have not been tested.

Western Blot (WB) of anti-SLC2A5 antibody

Western blot analysis of SLC2A5 expression in rat brain extract (lane 1), and K562 whole cell lysates (lane 2). SLC2A5 at 55KD was detected using rabbit anti-SLC2A5 Antigen Affinity purified polyclonal antibody at 0.5ug/mL. The blot was developed using chemiluminescence (ECL) method.
Rabbit Anti-SLC2A5 Polyclonal Antibody – Cat# MBS178460

Immunohistochemistry (IHC) of anti-SLC2A5 antibody

SLC2A5 was detected in paraffin-embedded sections of rat intestine cancer tissues using rabbit anti-SLC2A5 Antigen Affinity purified polyclonal antibody at 1ug/mL. The immunohistochemical section was developed using SABC method.
Rabbit Anti-SLC2A5 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS178460

Immunohistochemistry (IHC) of anti-SLC2A5 antibody

SLC2A5 was detected in paraffin-embedded sections of human intestinal cancer tissues using rabbit anti-SLC2A5 Antigen Affinity purified polyclonal antibody at 1 ug/mL. The immunohistochemical section was developed using SABC method.
Rabbit Anti-SLC2A5 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS178460

Product References and Citations for anti-SLC2A5 antibody

1. Burant, C. F., Takeda, J., Brot-Laroche, E., Bell, G. I., Davidson, N. O.Fructose transporter in human spermatozoa and small intestine is GLUT5.J. Biol. Chem. 267: 14523-14526, 1992.
2. Davidson, N. O., Hausman, A. M. L., Ifkovits, C. A., Buse, J. B., Gould, G. W., Burant, C. F., Bell, G. I.Human intestinal glucose transporter expression and localization of GLUT5.Am. J. Physiol. 262: C795-C800, 1992.
3. Kayano, T., Burant, C. F., Fukumoto, H., Gould, G. W., Fan, Y. S., Eddy, R. L., Byers, M. G., Shows, T. B., Seino, S., Bell, G. I.Human facilitative glucose transporters: isolation, functional characterization, and gene localization of cDNAs encoding an isoform (GLUT5) expressed in small intestine, kidney, muscle, and adipose tissue and an unusual glucose transporter pseudogene-like sequence (GLUT6).J. Biol. Chem. 265: 13276-13282, 1990.

Other Notes

Small volumes of anti-SLC2A5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SLC2A5 purchase

MBS178460 is an antibody targeting SLC2A5. Reactive in Human, Rat
No cross reactivity with other proteins.. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC2A5. It may not necessarily be applicable to this product.

NCBI GI #
207447703
NCBI GeneID
6518
NCBI Accession #
NP_001129057.1
UniProt Primary Accession #
P22732
UniProt Secondary Accession #
Q14770; Q5T977; Q8IVB3
UniProt Related Accession #
P22732
GenBank Nucleotide #
NM_001135585.1
NCBI Official Full Name
solute carrier family 2, facilitated glucose transporter member 5 isoform 2
NCBI Official Synonym Full Names
solute carrier family 2 member 5
NCBI Official Symbol
SLC2A5
NCBI Official Synonym Symbols
GLUT5; GLUT-5
UniProt Protein Name
Solute carrier family 2, facilitated glucose transporter member 5
UniProt Synonym Protein Names
Fructose transporter; Glucose transporter type 5, small intestine; GLUT-5
Protein Family
Solute carrier family
UniProt Gene Name
SLC2A5
UniProt Synonym Gene Names
GLUT5; GLUT-5
UniProt Entry Name
GTR5_HUMAN
NCBI Protein Information
solute carrier family 2, facilitated glucose transporter member 5

NCBI Summary for SLC2A5

The protein encoded by this gene is a fructose transporter responsible for fructose uptake by the small intestine. The encoded protein also is necessary for the increase in blood pressure due to high dietary fructose consumption. [provided by RefSeq, Jun 2016]

UniProt Comments for SLC2A5

GLUT5: an integral membrane facilitative glucose transporter. One of 13 members of the human equilibrative glucose transport protein family. Plays an important role in fructose absorption by the intestine. Expressed primarily in the jejunal region of the small intestine. Expressed at low levels in human kidney, skeletal muscle, adipocytes, microglial cells and in the human blood-brain barrier.

Protein type: Transporter, SLC family; Membrane protein, integral; Membrane protein, multi-pass; Transporter

Chromosomal Location of Human Ortholog: 1p36.2

Cellular Component: apical plasma membrane; integral to plasma membrane; plasma membrane; sarcolemma

Molecular Function: fructose transmembrane transporter activity; glucose transmembrane transporter activity

Biological Process: carbohydrate metabolic process; fructose transport; glucose transport; hexose transport; regulation of systemic arterial blood pressure mediated by a chemical signal; response to fructose stimulus
Show more

Research Articles on SLC2A5

1. SLC2A5-inhibits the human normal adjacent lung adenocarcinoma cytoplasmic pro-B cell development mechanism network.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-SLC2A5 antibody

 Products by Pathway  Pathway Diagram
 Carbohydrate Digestion And Absorption Pathway antibodies  Carbohydrate Digestion And Absorption Pathway Diagram
 Carbohydrate Digestion And Absorption Pathway antibodies  Carbohydrate Digestion And Absorption Pathway Diagram
 Class II GLUTs Pathway antibodies  Class II GLUTs Pathway Diagram
 Facilitative Na+-independent Glucose Transporters Pathway antibodies  Facilitative Na+-independent Glucose Transporters Pathway Diagram
 Glycolysis And Gluconeogenesis Pathway antibodies  Glycolysis And Gluconeogenesis Pathway Diagram
 Hexose Transport Pathway antibodies  Hexose Transport Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Carbohydrates Pathway antibodies  Metabolism Of Carbohydrates Pathway Diagram
 SLC-mediated Transmembrane Transport Pathway antibodies  SLC-mediated Transmembrane Transport Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram

Diseases associated with anti-SLC2A5 antibody

 Disease Name  Pubmed Publications
 Hypertension Antibodies  >10 publications with SLC2A5 and Hypertension
 Insulin Resistance Antibodies  >6 publications with SLC2A5 and Insulin Resistance
 Kidney Diseases Antibodies  >5 publications with SLC2A5 and Kidney Diseases
 Liver Diseases Antibodies  >4 publications with SLC2A5 and Liver Diseases
 Necrosis Antibodies  >4 publications with SLC2A5 and Necrosis
 Fibrosis Antibodies  >3 publications with SLC2A5 and Fibrosis
 Inflammation Antibodies  >3 publications with SLC2A5 and Inflammation
 Hypertrophy Antibodies  >3 publications with SLC2A5 and Hypertrophy
 Fatty Liver Antibodies  >2 publications with SLC2A5 and Fatty Liver
 Hyperglycemia Antibodies  >2 publications with SLC2A5 and Hyperglycemia

Organs/Tissues associated with anti-SLC2A5 antibody

 Organ/Tissue Name  Pubmed Publications
 Intestine Antibodies  >28 publications with SLC2A5 and Intestine
 Blood Antibodies  >13 publications with SLC2A5 and Blood
 Kidney Antibodies  >10 publications with SLC2A5 and Kidney
 Muscle Antibodies  >9 publications with SLC2A5 and Muscle
 Brain Antibodies  >7 publications with SLC2A5 and Brain
 Heart Antibodies  >4 publications with SLC2A5 and Heart
 Ovary Antibodies  >4 publications with SLC2A5 and Ovary
 Uterus Antibodies  >3 publications with SLC2A5 and Uterus
 Testis Antibodies  >3 publications with SLC2A5 and Testis
 Stomach Antibodies  >2 publications with SLC2A5 and Stomach
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