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TACC1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS178687

Rabbit IgG polyclonal antibody for Transforming acidic coiled-coil-containing protein 1(TACC1) detection.Background: Transforming acidic coiled-coil-containing protein 1 is a protein that in humans is encoded by the TACC1 gene. This locus may represent a… More details

$210 / 0.01 mg +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
TACC1, Polyclonal Antibody
Full Product Name
Anti-TACC1 Antibody
Product Gene Name
Product Synonym Names
Ga 55; Ga55; TACC 1; Tacc1; Taxin 1; Taxin-1; Taxin1; O75410; Transforming acidic coiled-coil-containing protein 1; transforming acidic coiled-coil containing protein 1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Lyophilized
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Purity/Purification
Immunogen affinity purified.
Preparation and Storage
Store at -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Molecular Weight
17,815 Da
OMIM
AF049910 mRNA
3D Structure
ModBase 3D Structure for O75410
Notes
Tested Species: In-house tested species with positive results.
Other applications have not been tested.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human TACC1 (196-235aa MTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKP), different from the related mouse sequence by fourteen amino acids.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-TACC1 antibody
Western Blot (WB)
Application Notes for anti-TACC1 antibody
Western Blot: 0.1-0.5ug/ml

Western Blot (WB) of anti-TACC1 antibody

Western blot analysis of TACC1 expression in mouse testis extract (lane 1) and U87 whole cell lysates (lane 2). TACC1 at 100KD was detected using rabbit anti- TACC1 Antigen Affinity purified polyclonal antibody at 0.5ug/mL. The blot was developed using chemiluminescence (ECL) method.
Rabbit Anti-TACC1 Polyclonal Antibody – Cat# MBS178687

Product References and Citations for anti-TACC1 antibody

1. Delaval B, Ferrand A, Conte N, Larroque C, Hernandez-Verdun D, Prigent C, Birnbaum D (Jun 2004). "Aurora B -TACC1 protein complex in cytokinesis".Oncogene. 23 (26): 4516-22.
2. Conte N, Delaval B, Ginestier C, Ferrand A, Isnardon D, Larroque C, Prigent C, Séraphin B, Jacquemier J, Birnbaum D (Nov 2003). "TACC1-chTOG-Aurora A protein complex in breast cancer". Oncogene. 22 (50): 8102-16.

Other Notes

Small volumes of anti-TACC1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TACC1 purchase

MBS178687 is an antibody targeting TACC1. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TACC1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
transforming acidic coiled-coil-containing protein 1 isoform 2
NCBI Official Synonym Full Names
transforming acidic coiled-coil containing protein 1
NCBI Official Symbol
TACC1
NCBI Official Synonym Symbols
Ga55
UniProt Protein Name
Transforming acidic coiled-coil-containing protein 1
UniProt Synonym Protein Names
Gastric cancer antigen Ga55; Taxin-1
UniProt Gene Name
TACC1
UniProt Synonym Gene Names
KIAA1103
NCBI Protein Information
transforming acidic coiled-coil-containing protein 1

NCBI Summary for TACC1

This locus may represent a breast cancer candidate gene. It is located close to FGFR1 on a region of chromosome 8 that is amplified in some breast cancers. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009]

UniProt Comments for TACC1

TACC1: Likely involved in the processes that promote cell division prior to the formation of differentiated tissues. Belongs to the TACC family. 8 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell development/differentiation; Cytoskeletal

Chromosomal Location of Human Ortholog: 8p11.22

Cellular Component: cytoplasm; intermediate filament cytoskeleton; microtubule cytoskeleton

Molecular Function: protein binding

Biological Process: cell proliferation; cerebral cortex development; microtubule cytoskeleton organization and biogenesis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-TACC1 antibody

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