Synapsin I (SYN1) Antibody – Rabbit Polyclonal

Rabbit IgG polyclonal antibody for Synapsin-1(SYN1) detection.
Background: Synapsin I, is the collective name for Synapsin Ia and Synapsin Ib, two nearly identical phosphoproteins that in humans are encoded by the SYN1 gene. This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

1. "Entrez Gene: SYN1 synapsin I".
2. Huttner WB, Schiebler W, Greengard P, De Camilli P (May 1983). "Synapsin I (protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation". J. Cell Biol. 96 (5): 1374-88.
3. Südhof TC (May 1990). "The structure of the human synapsin I gene and protein". J. Biol. Chem. 265 (14): 7849-52.

Small volumes of anti-SYN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS178855 is an antibody targeting SYN1. Also known as Anti-Synapsin I Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.