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Troponin T (TNNT2) Antibody – Rabbit Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS179571

Activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH. Involved in menthol sensation. Permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium. More details

$210 / 0.03 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Troponin T (TNNT2), Monoclonal Antibody
Full Product Name
Anti-Troponin T Rabbit Monoclonal Antibody
Product Gene Name
Product Synonym Names
Troponin T; cardiac muscle; TnTc; Cardiac muscle troponin T; cTnT; TNNT2
Clonality
Monoclonal
Isotype
Rabbit IgG
Clone Number
FDC-20
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid; Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Purity/Purification
Affinity-chromatography
Preparation and Storage
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Molecular Weight
Observed Molecular Weight: 40 kDa
Calculated molecular weight: 35924 MW
OMIM
S64668 mRNA
3D Structure
ModBase 3D Structure for P45379
Immunogen
A synthesized peptide derived from human Troponin T
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-TNNT2 antibody
Immunohistochemistry (IHC), Western Blot (WB)
Application Notes for anti-TNNT2 antibody
Dilute the sample so that the expexted range of concentrations fall within the detection range of this kit.
If the expected range of concentration is unknown, a pilot test should be conducted to decide the optimal dilution ration of your samples.
Some PubMed article(s) cites the expression level of this target are as follows: Internal QC testing used:
WB: 1:5000-1:20000
IHC: 1:50-1:200
Positive Control:
WB: human fetal heart
IHC: human heart muscle tissue

Western Blot (WB) of anti-TNNT2 antibody

Western blot analysis of Troponin T expression in human fetal heart lysate (MBS179571).
Rabbit Anti-TNNT2 Monoclonal Antibody – Cat# MBS179571

Immunohistochemistry (IHC) of anti-TNNT2 antibody

Immunohistochemical analysis of paraffin-embedded human heart muscle, using Troponin T Antibody.
Rabbit Anti-TNNT2 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS179571

Other Notes

Small volumes of anti-TNNT2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TNNT2 purchase

MBS179571 is an antibody targeting TNNT2. Also known as Anti-Troponin T Rabbit Monoclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TNNT2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
troponin T, cardiac muscle isoform 1
NCBI Official Synonym Full Names
troponin T2, cardiac type
NCBI Official Symbol
TNNT2
NCBI Official Synonym Symbols
CMH2; RCM3; TnTC; cTnT; CMD1D; CMPD2; LVNC6
UniProt Protein Name
Troponin T, cardiac muscle
UniProt Synonym Protein Names
Cardiac muscle troponin T; cTnT
Protein Family
UniProt Gene Name
TNNT2
UniProt Synonym Gene Names
TnTc; cTnT
NCBI Protein Information
troponin T, cardiac muscle

NCBI Summary for TNNT2

The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined. [provided by RefSeq, Jul 2008]
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UniProt Comments for TNNT2

Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TNNT2 antibody

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