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Dysferlin (DYSF) Antibody – Rabbit Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS179601

Anti-Dysferlin Rabbit Monoclonal AntibodyKey calcium ion sensor involved in the Ca(2+)-triggered synaptic vesicle-plasma membrane fusion. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing… More details

$210 / 0.03 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Dysferlin, Monoclonal Antibody
Full Product Name
Anti-Dysferlin Rabbit Monoclonal Antibody
Product Gene Name
Product Synonym Names
Anti-Dysferlin Rabbit Monoclonal Antibody
Clonality
Monoclonal
Clone Number
EGO-4
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid; Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCI, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Purity/Purification
Affinity-chromatography
Concentration
0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure. (lot specific)
Preparation and Storage
Store at -20°C. Avoid repeated freezing and thawing.
OMIM
AF075575 mRNA
3D Structure
ModBase 3D Structure for O75923
Immunogen
A synthesized peptide derived from human Dysferlin.

Product Categories/Family for anti-DYSF antibody

ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-DYSF antibody
Western Blot (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
Application Notes for anti-DYSF antibody
WB: 1:500-1:1000
IHC: 1:50-1:200
ICC/IF: 1:50-1:200

Western Blot (WB) of anti-DYSF antibody

Western blot analysis of dysferlin expression in mouse skeletal muscle tissue lysate
Rabbit Anti-DYSF Monoclonal Antibody – Cat# MBS179601

Other Notes

Small volumes of anti-DYSF antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DYSF purchase

MBS179601 is an antibody targeting DYSF. Also known as Anti-Dysferlin Rabbit Monoclonal Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DYSF. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
dysferlin isoform 2
NCBI Official Synonym Full Names
dysferlin
NCBI Official Symbol
DYSF
NCBI Official Synonym Symbols
MMD1; FER1L1; LGMD2B
UniProt Protein Name
Dysferlin
UniProt Synonym Protein Names
Dystrophy-associated fer-1-like protein; Fer-1-like protein 1
Protein Family
UniProt Gene Name
DYSF
UniProt Synonym Gene Names
FER1L1
NCBI Protein Information
dysferlin

NCBI Summary for DYSF

The protein encoded by this gene belongs to the ferlin family and is a skeletal muscle protein found associated with the sarcolemma. It is involved in muscle contraction and contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. In addition, the protein encoded by this gene binds caveolin-3, a skeletal muscle membrane protein which is important in the formation of caveolae. Specific mutations in this gene have been shown to cause autosomal recessive limb girdle muscular dystrophy type 2B (LGMD2B) as well as Miyoshi myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2008]
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UniProt Comments for DYSF

Key calcium ion sensor involved in the Ca2+-triggered synaptic vesicle-plasma membrane fusion. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress ().

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-DYSF antibody

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