Mouse Anti-CD140b Monoclonal Antibody – Cat# MBS1800068

CD140b Antibody – Mouse Monoclonal

Name: CD140b Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS1800068
Price: 385 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1800068

CD140b / PDGF-RB (platelet-derived growth factor receptor beta) is a cell surface receptor for members of platelet-derived growth factor family, whose intracellular part contains a tyrosine kinase domain. CD140b forms homodimers, or heterodimerizes with… More details

$385 / 100 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CD140b, Monoclonal Antibody

Full Product Name

Anti-Hu CD140b PE

Product Gene Name

anti-CD140b antibody

Product Synonym Gene Name

PDGFRB

Product Synonym Names

platelet derived growth factor receptor beta; PDGFRB; PDGF receptor beta; PDGFR1

Clonality

Monoclonal

Isotype

IgG1

Clone Number

18A2

Host

Mouse

Species Reactivity

Human

Form/Format

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Specificity

The monoclonal antibody 18A2 recognizes an extracellular epitope of CD140b / PDGF-RB, the 180-190 kDa beta chain of platelet-derived growth factor receptor, which is widely expressed on a variety of mesenchymal-derived cells and plays pro-proliferative roles.

Preparation and Storage

Store in the dark at 2-8 degree C. Do not freeze. Avoid prolonged exposure to light.

Matching Pairs

Unconjugated Antibody: CD140b Clone #18A2 (MBS1800066)
PE Conjugated Antibody: CD140b Clone #18A2 (MBS1800068)

3D Structure

ModBase 3D Structure for Q59F04

Immunogen

CD140b-transfected NIH 3T3 cells

Excitation Laser

Blue (488 nm)

Preparation

Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size exclusion chromatography.

Conjugation

Applications Tested/Suitable for anti-CD140b antibody

Flow Cytometry (FC: QC Tested)

Application Notes for anti-CD140b antibody

FC: The reagent is designed for analysis of human blood cells using 20ul reagent / 100 ul of whole blood or 10⁶ cells in suspension. The content of vial (2ml) is sufficient for 100 tests.

Other Notes

Small volumes of anti-CD140b antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD140b purchase

MBS1800068 is an antibody targeting CD140b. Also known as Anti-Hu CD140b PE. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CD140b. It may not necessarily be applicable to this product.

NCBI GI #

74707129

NCBI GeneID

5159

UniProt Primary Accession #

Q59F04

UniProt Related Accession #

P09619

NCBI Official Full Name

Platelet-derived growth factor receptor beta variant

NCBI Official Synonym Full Names

platelet derived growth factor receptor beta

NCBI Official Symbol

PDGFRB

NCBI Official Synonym Symbols

IMF1; KOGS; IBGC4; JTK12; PDGFR; PENTT; CD140B; PDGFR1; PDGFR-1

NCBI Protein Information

platelet-derived growth factor receptor beta

NCBI Summary for CD140b

The protein encoded by this gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB). This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the ETV6 gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Aug 2017]

Research Articles on CD140b

1. PDGFRB mutations do not play a role in odontogenic myxoma pathogenesis

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.