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CD205 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1800688

CD205, also known as DEC-205, is an endocytic receptor of macrophage mannose receptor family. This 205 kDa C-type lectin transmembrane protein mediates adsorptive uptake and its intracellular domain contains coated pit localization sequence and distal acidic… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD205, Monoclonal Antibody
Full Product Name
Anti-Hu CD205 PE
Product Gene Name
Product Synonym Gene Name
LY75
Product Synonym Names
lymphocyte antigen 75; DEC-205; LY75; CLEC13B
Clonality
Monoclonal
Isotype
IgG1 kappa
Clone Number
HD30
Host
Mouse
Species Reactivity
Human
Form/Format
Stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide
Purity/Purification
The purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Specificity
The mouse monoclonal antibody HD30 recognizes an extracellular epitope of CD205, an approx. 200 kDa C-type lectin transmembrane protein of the MMR (macrophage mannose receptor) family, expressed at high levels on dendritic cells and thymic epithelial cells, and at low levels on lymphocytes, NK cells and monocytes.
Preparation and Storage
Store in the dark at 2-8 degree C. Do not freeze. Avoid prolonged exposure to light.
Matching Pairs
Unconjugated Antibody: CD205 Clone #HD30 (MBS1800687)
PE Conjugated Antibody: CD205 Clone #HD30 (MBS1800688)
OMIM
604524
3D Structure
ModBase 3D Structure for O60449
Immunogen
Recombinant Fc-tagged human CD205
Conjugation
PE
Applications Tested/Suitable for anti-CD205 antibody
Flow Cytometry (FC/FACS)
Application Notes for anti-CD205 antibody
FC/FACS: QC tested

Flow Cytometry (FC/FACS) of anti-CD205 antibody

Flow cytometry multicolor surface staining of human lymphocytes stained using anti-human CD205 (HD30) PE antibody (10 ul reagent / 100 ul of peripheral whole blood) and anti-human HLA-DR (MEM-12) APC antibody (10 ul reagent / 100 ul of peripheral whole blood).
Mouse Anti-CD205 Monoclonal Antibody – Cat# MBS1800688

Flow Cytometry (FC/FACS) of anti-CD205 antibody

Separation of human monocytes (red-filled) from CD205 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD205 (HD30) PE antibody (10 ul reagent / 100 ul of peripheral whole blood).
Mouse Anti-CD205 Monoclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS1800688

Flow Cytometry (FC/FACS) of anti-CD205 antibody

Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD205 (HD30) PE antibody (10 ul reagent / 100 ul of peripheral whole blood).
Mouse Anti-CD205 Monoclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS1800688

Other Notes

Small volumes of anti-CD205 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD205 purchase

MBS1800688 is an antibody targeting CD205. Also known as Anti-Hu CD205 PE. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CD205. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
LY75-CD302 fusion protein isoform 1
NCBI Official Synonym Full Names
lymphocyte antigen 75
NCBI Official Symbol
LY75
NCBI Official Synonym Symbols
CD205; LY-75; CLEC13B; DEC-205; GP200-MR6
UniProt Protein Name
Lymphocyte antigen 75
UniProt Synonym Protein Names
C-type lectin domain family 13 member B; DEC-205; gp200-MR6
Protein Family
UniProt Gene Name
LY75
UniProt Synonym Gene Names
CD205; CLEC13B; Ly-75
UniProt Entry Name
LY75_HUMAN
NCBI Protein Information
lymphocyte antigen 75

UniProt Comments for CD205

LY75: Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen- processing compartment. Causes reduced proliferation of B-lymphocytes. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 2q24

Cellular Component: integral to plasma membrane

Molecular Function: receptor activity; carbohydrate binding

Biological Process: endocytosis; immune response; inflammatory response
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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