Mouse Anti-GAPDHS Antibody – Cat# MBS1800769

GAPDHS Antibody – Mouse

Name: GAPDHS Antibody; Mouse; Pig/Human-Reactive; Pig/Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS1800769
Price: 435 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1800769

GAPDHS (the sperm-specific glyceraldehyde phosphate dehydrogenase, also known as GAPD2, GAPDS, HSD-35, or GAPDH-2, is a glycolytic enzyme that plays an important role in carbohydrate metabolism. Like its somatic cell counterpart, this sperm-specific enzyme… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GAPDHS, Antibody

Full Product Name

Anti-GAPDHS FITC

Product Gene Name

anti-GAPDHS antibody

Product Synonym Names

glyceraldehyde-3-phosphate dehydrogenase, spermato; spermatogenic glyceraldehyde-3-phosphate dehydrogenase; SGAPDH; HSD-35

Isotype

IgM

Clone Number

Hs-8

Host

Mouse

Species Reactivity

Pig, Human

Form/Format

Stabilizing Tris buffered saline (TBS) solution with 15 mM sodium azide

Purity/Purification

The purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions. The conjugate is purified by size-exclusion chromatography.

Specificity

The antibody Hs-8 reacts with GAPDHS, the sperm-specific glyceraldehyde phosphate dehydrogenase, which is an intra-acrosomal protein.

Preparation and Storage

Store in the dark at 2-8 degree C. Do not freeze. Avoid prolonged exposure to light.

Matching Pairs

Unconjugated Antibody: GAPDHS Clone #Hs-8 (MBS1800768)
FITC Conjugated Antibody: GAPDHS Clone #Hs-8 (MBS1800769)

OMIM

609169

3D Structure

ModBase 3D Structure for O14556

Immunogen

Freshly ejaculated human sperms were washed in PBS and extracted in 3% acetic acid, 10% glycerol, 30 mM benzaminidine. The acid extract was dialyzed against 0.2% acetic acid and subsequently used for immunization.

Conjugation

FITC

Applications Tested/Suitable for anti-GAPDHS antibody

Flow Cytometry (FC/FACS)

Application Notes for anti-GAPDHS antibody

FC/FACS: QC tested

Other Notes

Small volumes of anti-GAPDHS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GAPDHS purchase

MBS1800769 is an antibody targeting GAPDHS. Also known as Anti-GAPDHS FITC. Reactive in Pig, Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for GAPDHS. It may not necessarily be applicable to this product.

NCBI GI #

7657116

NCBI GeneID

26330

NCBI Accession #

NP_055179

UniProt Primary Accession #

O14556

UniProt Related Accession #

O14556

GenBank Nucleotide #

NP_055179.1

NCBI Official Full Name

glyceraldehyde-3-phosphate dehydrogenase, testis-specific

NCBI Official Synonym Full Names

glyceraldehyde-3-phosphate dehydrogenase, spermatogenic

NCBI Official Symbol

GAPDHS

NCBI Official Synonym Symbols

GAPD2; GAPDS; HSD-35; GAPDH-2; HEL-S-278

UniProt Protein Name

Glyceraldehyde-3-phosphate dehydrogenase, testis-specific

UniProt Synonym Protein Names

Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2; GAPDH-2; Spermatogenic glyceraldehyde-3-phosphate dehydrogenase

Protein Family

Glyceraldehyde-3-phosphate dehydrogenase

UniProt Gene Name

GAPDHS

UniProt Synonym Gene Names

GAPD2; GAPDH2; GAPDS; GAPDH-2

UniProt Entry Name

G3PT_HUMAN

NCBI Protein Information

glyceraldehyde-3-phosphate dehydrogenase, testis-specific

NCBI Summary for GAPDHS

This gene encodes a protein belonging to the glyceraldehyde-3-phosphate dehydrogenase family of enzymes that play an important role in carbohydrate metabolism. Like its somatic cell counterpart, this sperm-specific enzyme functions in a nicotinamide adenine dinucleotide-dependent manner to remove hydrogen and add phosphate to glyceraldehyde 3-phosphate to form 1,3-diphosphoglycerate. During spermiogenesis, this enzyme may play an important role in regulating the switch between different energy-producing pathways, and it is required for sperm motility and male fertility. [provided by RefSeq, Jul 2008]

Research Articles on GAPDHS

1. GAPDS overexpression antagonize high glucose-induced apoptosis by controlling reactive oxygen species accumulation in TM3 cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GAPDHS antibody

Reference Product	PubMed Publications
PGK2 antibody	>2 publications with GAPDHS and PGK2
ALDOA antibody	>1 publications with GAPDHS and ALDOA
PGK1 antibody	>1 publications with GAPDHS and PGK1

Pathways associated with anti-GAPDHS antibody

Products by Pathway	Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Gluconeogenesis Pathway antibodies	Gluconeogenesis Pathway Diagram
Glucose Metabolism Pathway antibodies	Glucose Metabolism Pathway Diagram
Glycogen Storage Diseases Pathway antibodies	Glycogen Storage Diseases Pathway Diagram
Glycolysis Pathway antibodies	Glycolysis Pathway Diagram
Glycolysis / Gluconeogenesis Pathway antibodies	Glycolysis / Gluconeogenesis Pathway Diagram
Glycolysis / Gluconeogenesis Pathway antibodies	Glycolysis / Gluconeogenesis Pathway Diagram
Glycolysis And Gluconeogenesis Pathway antibodies	Glycolysis And Gluconeogenesis Pathway Diagram
Metabolic Pathways antibodies	Metabolic Pathways Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram

Diseases associated with anti-GAPDHS antibody

Disease Name	Pubmed Publications
Infertility, Male Antibodies	>5 publications with GAPDHS and Infertility, Male
Genital Diseases, Male Antibodies	>3 publications with GAPDHS and Genital Diseases, Male
Nervous System Diseases Antibodies	>3 publications with GAPDHS and Nervous System Diseases
Mental Disorders Antibodies	>2 publications with GAPDHS and Mental Disorders
Alzheimer Disease Antibodies	>2 publications with GAPDHS and Alzheimer Disease
Disease Models, Animal Antibodies	>1 publications with GAPDHS and Disease Models, Animal
Oligospermia Antibodies	>1 publications with GAPDHS and Oligospermia
Neoplasm Metastasis Antibodies	>1 publications with GAPDHS and Neoplasm Metastasis
Liver Diseases Antibodies	>1 publications with GAPDHS and Liver Diseases

Organs/Tissues associated with anti-GAPDHS antibody

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>12 publications with GAPDHS and Muscle
Testis Antibodies	>6 publications with GAPDHS and Testis
Skin Antibodies	>1 publications with GAPDHS and Skin
Brain Antibodies	>1 publications with GAPDHS and Brain