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CD62L Antibody – Rat Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1800962

CD62L (L-selectin) is an adhesion glycoprotein that is constitutively expressed on the cell surface of leukocytes and mediates their homing to inflammatory sites and peripheral lymph nodes by enabling rolling along the venular wall. CD62L is also involved in… More details

$290 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD62L, Monoclonal Antibody
Full Product Name
Anti-Ms CD62L Purified Low Endotoxin
Product Gene Name
Product Synonym Gene Name
Sell
Product Synonym Names
selectin L; L-selectin; Lsel; Sell; Lam-1; Lam1; Lecam; Leu8; Lnhr; Lyam1; Plnhr
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
Mel-14
Host
Rat
Species Reactivity
Mouse
Form/Format
Low endotoxin azide free phosphate buffered saline (PBS) solution, 0.2 um filter sterilized. Endotoxin level is less than 0.01 EU/ug of the protein, as determined by the LAL test.
Purity/Purification
Purified by Protein-G Affinity Chromatography
Concentration
1 mg/ml (lot specific)
Specificity
The rat monoclonal antibody MEL-14 reacts with an extracellular epitope of murine CD62L (L-selectin), a 75 kDa single chain type I glycoprotein expressed on most peripheral blood B lymphocytes, T lymphocytes, monocytes and granulocytes; it is also present on a subset of NK cells and certain hematopoietic malignant cells.
Preparation and Storage
Store at 2-8 degree C.
Matching Pairs
Unconjugated Antibody: CD62L Clone #Mel-14 (MBS1800961)
Unconjugated Low Endotoxin Antibody: CD62L Clone #Mel-14 (MBS1800962)
3D Structure
ModBase 3D Structure for Q3TCF3
Immunogen
C3H/eb mouse B cell lymphoma 38C-13
Applications Tested/Suitable for anti-CD62L antibody
Flow Cytometry (FC/FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC) Frozen/Paraffin, Immunocytochemistry (ICC), Functional
Application Notes for anti-CD62L antibody
FC/FACS: QC tested

Flow Cytometry (FC/FACS) of anti-CD62L antibody

Separation of murine splenocytes stained anti-mouse CD62L (Mel-14) purified antibody (concentration in sample 4 ug/ml, DAR APC, red-filled) from murine splenocytes unstained by primary antibody (DAR APC, black-dashed) in flow cytometry analysis (surface staining).
Rat Anti-CD62L Monoclonal Antibody – Cat# MBS1800962

Flow Cytometry (FC/FACS) of anti-CD62L antibody

Flow cytometry surface staining pattern of murine splenocytes stained using anti-mouse CD62L (Mel-14) purified antibody (concentration in sample 4 ug/ml, DAR APC).
Rat Anti-CD62L Monoclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS1800962

Other Notes

Small volumes of anti-CD62L antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD62L purchase

MBS1800962 is an antibody targeting CD62L. Also known as Anti-Ms CD62L Purified Low Endotoxin. Reactive in Mouse. Host: Rat.

Additional Details

NCBI/Uniprot data below describe general gene information for CD62L. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
NOD-derived CD11c +ve dendritic cells cDNA, RIKEN full-length enriched library, clone:F630118J02 product:selectin, lymphocyte, full insert sequence
NCBI Official Synonym Full Names
selectin, lymphocyte
NCBI Official Symbol
Sell
NCBI Official Synonym Symbols
Lnhr; CD62L; Ly-22; Lyam1; Ly-m22; Lyam-1; LECAM-1; AI528707; L-selectin
UniProt Protein Name
L-selectin
Protein Family
UniProt Gene Name
Sell
UniProt Entry Name
Q3TCF3_MOUSE
NCBI Protein Information
L-selectin

UniProt Comments for CD62L

SELL: Cell surface adhesion protein. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. Belongs to the selectin/LECAM family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Cellular Component: cell surface; membrane; integral to membrane; plasma membrane; external side of plasma membrane

Molecular Function: protein binding; protease binding; cell adhesion molecule binding; carbohydrate binding; glycolipid binding

Biological Process: regulation of apoptosis; cell adhesion; response to ATP
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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