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CD41 Antibody – Mouse

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1800976

CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, alpha and 23 kDa b, beta) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of… More details

$295 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD41, Antibody
Full Product Name
Anti-Hu CD41 Purified
Product Gene Name
Product Synonym Gene Name
ITGA2B
Product Synonym Names
integrin subunit alpha 2b; Platelet GPIIb; Integrin alpha-IIb; GPalpha IIb; GPIIb; GTA
Isotype
IgG1
Clone Number
MEM-06
Host
Mouse
Species Reactivity
Human
Form/Format
Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Purity/Purification
Purified by Protein-A Affinity Chromatography
Concentration
1 mg/ml (lot specific)
Specificity
The antibody MEM-06 reacts with an extracellular epitope of CD41 (GPIIb), a transmembrane glycoprotein (integrin family) composed of two chains GPIIb alpha (heavy chain; 120 kDa) and GPIIb beta (light chain; 23 kDa). CD41 is mainly expressed on platelets and megakaryocytes.
Preparation and Storage
Store at 2-8 degree C.
Matching Pairs
Unconjugated Antibody: CD41 Clone #MEM-06 (MBS1800976)
APC Conjugated Antibody: CD41 Clone #MEM-06 (MBS1800977)
Matching Pairs
Unconjugated Antibody: CD41 Clone #MEM-06 (MBS1800976)
Biotin Conjugated Antibody: CD41 Clone #MEM-06 (MBS1800978)
OMIM
273800
3D Structure
ModBase 3D Structure for P08514
Immunogen
Leukocytes of patient suffering from LGL-type leukaemia.
Applications Tested/Suitable for anti-CD41 antibody
Flow Cytometry (FC/FACS)
Application Notes for anti-CD41 antibody
FC/FACS: QC tested

Flow Cytometry (FC/FACS) of anti-CD41 antibody

Separation of human CD41 positive thrombocytes (red-filled) from CD41 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD41 (MEM-06) purified antibody (concentration in sample 1 ug/ml) GAM APC.
Mouse Anti-CD41 Antibody – Cat# MBS1800976

Flow Cytometry (FC/FACS) of anti-CD41 antibody

Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD41 (MEM-06) purified antibody (concentration in sample 1 ug/ml) GAM APC.
Mouse Anti-CD41 Antibody, Flow Cytometry (FC/FACS) – Cat# MBS1800976

Other Notes

Small volumes of anti-CD41 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD41 purchase

MBS1800976 is an antibody targeting CD41. Also known as Anti-Hu CD41 Purified. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CD41. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
integrin alpha-IIb preproprotein
NCBI Official Synonym Full Names
integrin subunit alpha 2b
NCBI Official Symbol
ITGA2B
NCBI Official Synonym Symbols
GT; GTA; CD41; GP2B; HPA3; CD41B; GPIIb; BDPLT2; BDPLT16; PPP1R93
UniProt Protein Name
Integrin alpha-IIb
UniProt Synonym Protein Names
GPalpha IIb; GPIIb; Platelet membrane glycoprotein IIb
Protein Family
UniProt Gene Name
ITGA2B
UniProt Synonym Gene Names
GP2B; ITGAB; GPIIb
UniProt Entry Name
ITA2B_HUMAN
NCBI Protein Information
integrin alpha-IIb

NCBI Summary for CD41

This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. [provided by RefSeq, Jan 2016]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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