• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

CD16 Antibody – Mouse

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1801052

CD16 (FcgammaRIII) is a 50-65 kDa glycoprotein serving as a low affinity IgG receptor. Human FcgammaRIII is expressed in two forms - FcgammaRIII-A and -B. FcgammaRIII-A is a transmembrane protein of monocytes, macrophages, NK cells and a subset of T cells. It… More details

$295 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD16, Antibody
Full Product Name
Anti-Hu CD16 Purified Low Endotoxin
Product Gene Name
anti-CD16 antibody
Product Synonym Names
FcgammaRIII; Low affinity immunoglobulin gamma Fc region receptor III; IGFR3; FCRIII
Isotype
IgG1
Clone Number
MEM-154
Host
Mouse
Species Reactivity
Human
Form/Format
Low endotoxin azide free phosphate buffered saline (PBS) solution, 0.2 um filter sterilized. Endotoxin level is less than 0.01 EU/ug of the protein, as determined by the LAL test.
Purity/Purification
Purified by Protein-A Affinity Chromatography
Concentration
1 mg/ml (lot specific)
Specificity
The antibody MEM-154 reacts with an extracellular epitope on CD16 antigen that is residing in proximity to FG loop (probably BC or C'E loop). CD16 is a low affinity receptor for aggregated IgG (FcgammaRIII antigen). The antibody MEM-154 reacts with CD16+ granulocytes.
Preparation and Storage
Store at 2-8 degree C.
Matching Pairs
Unconjugated Antibody: CD16 Clone #MEM-154 (MBS1801051)
Unconjugated Low Endotoxin Antibody: CD16 Clone #MEM-154 (MBS1801052)
Immunogen
Human granulocytes
Applications Tested/Suitable for anti-CD16 antibody
Flow Cytometry (FC/FACS), Immunoprecipitation (IP), Western Blot (WB), Functional
Application Notes for anti-CD16 antibody
FC/FACS: QC tested

Flow Cytometry (FC/FACS) of anti-CD16 antibody

Separation of human neutrophil granulocytes (red-filled) from CD16 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD16 (MEM-154) purified antibody (low endotoxin, concentration in sample 2 ug/ml) GAM APC.
Mouse Anti-CD16 Antibody – Cat# MBS1801052

Flow Cytometry (FC/FACS) of anti-CD16 antibody

Flow cytometry surface staining pattern of human peripheral blood stained using anti-human CD16 (MEM-154) purified antibody (low endotoxin, concentration in sample 2 ug/ml) GAM APC.
Mouse Anti-CD16 Antibody, Flow Cytometry (FC/FACS) – Cat# MBS1801052

Other Notes

Small volumes of anti-CD16 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD16 purchase

MBS1801052 is an antibody targeting CD16. Also known as Anti-Hu CD16 Purified Low Endotoxin. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CD16. It may not necessarily be applicable to this product.

NCBI GI #
8176551
NCBI GeneID
2214
UniProt Related Accession #
P08637
NCBI Official Full Name
CD16, partial
NCBI Official Synonym Full Names
Fc fragment of IgG receptor IIIa
NCBI Official Symbol
FCGR3A
NCBI Official Synonym Symbols
CD16; FCG3; CD16A; FCGR3; IGFR3; IMD20; FCR-10; FCRIII; FCGRIII; FCRIIIA
Protein Family
CD160 antigen
NCBI Protein Information
low affinity immunoglobulin gamma Fc region receptor III-A

NCBI Summary for CD16

This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Show more

Research Articles on CD16

1. The FcgammaRIIIA(+) CD8 T cells were highly activated in a manner that correlated positively with expansion of the CD8 T cell compartment and with plasma levels of soluble mediators of antiviral immunity and inflammation such as IP-10, TNF, IL-6, and TNFRII.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CD16 antibody

 Reference Product  PubMed Publications
 FCGR1A antibody  >6 publications with CD16 and FCGR1A
 CD4 antibody  >4 publications with CD16 and CD4
 PTPRC antibody  >1 publications with CD16 and PTPRC

Pathways associated with anti-CD16 antibody

 Products by Pathway  Pathway Diagram
 Adaptive Immunity Signaling Pathway antibodies  Adaptive Immunity Signaling Pathway Diagram
 Fc Gamma R-mediated Phagocytosis Pathway antibodies  Fc Gamma R-mediated Phagocytosis Pathway Diagram
 Fc Gamma R-mediated Phagocytosis Pathway antibodies  Fc Gamma R-mediated Phagocytosis Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway antibodies  Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway Diagram
 Leishmaniasis Pathway antibodies  Leishmaniasis Pathway Diagram
 Leishmaniasis Pathway antibodies  Leishmaniasis Pathway Diagram
 Natural Killer Cell Mediated Cytotoxicity Pathway antibodies  Natural Killer Cell Mediated Cytotoxicity Pathway Diagram
 Natural Killer Cell Mediated Cytotoxicity Pathway antibodies  Natural Killer Cell Mediated Cytotoxicity Pathway Diagram
 Osteoclast Differentiation Pathway antibodies  Osteoclast Differentiation Pathway Diagram

Diseases associated with anti-CD16 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >57 publications with CD16 and Neoplasms
 Autoimmune Diseases Antibodies  >52 publications with CD16 and Autoimmune Diseases
 Lymphoma Antibodies  >32 publications with CD16 and Lymphoma
 Arthritis, Rheumatoid Antibodies  >26 publications with CD16 and Arthritis, Rheumatoid
 Lymphoma, Non-Hodgkin Antibodies  >24 publications with CD16 and Lymphoma, Non-Hodgkin
 Lupus Erythematosus, Systemic Antibodies  >18 publications with CD16 and Lupus Erythematosus, Systemic
 Intestinal Diseases Antibodies  >16 publications with CD16 and Intestinal Diseases
 Necrosis Antibodies  >16 publications with CD16 and Necrosis
 Inflammation Antibodies  >9 publications with CD16 and Inflammation
 Leukemia Antibodies  >8 publications with CD16 and Leukemia

Organs/Tissues associated with anti-CD16 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >89 publications with CD16 and Blood
 Ovary Antibodies  >5 publications with CD16 and Ovary
 Kidney Antibodies  >4 publications with CD16 and Kidney
 Lung Antibodies  >3 publications with CD16 and Lung
 Liver Antibodies  >2 publications with CD16 and Liver
 Brain Antibodies  >1 publications with CD16 and Brain
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000