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CLDN6 Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS188108

MBS188108 is a recombinant protein targeting CLDN6. Also known as Human CLDN6 Protein, mFc Tag. Host: HEK293 cells. Recombinant human CLDN6 Protein with C-terminal mouse Fc Tag. More details

$280 / 0.01 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CLDN6, Recombinant Protein
Full Product Name
Human CLDN6 Protein, mFc Tag
Product Gene Name
Product Synonym Names
Human CLDN6 Protein, mFc Tag; Claudin 6; Claudin-6; Skullin
Sequence
CLDN6(Met1 -Ala4)+(Gl n57-Gln78) +(Arg145-A rg158)+mFc (Pro99-Lys 330)
Host
HEK293 cells
Form/Format
Lyophilized from sterile PBS, pH 7.4. Normally 5%-57% trehalose is added as protectants before lyophilization.
Purity/Purification
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Preparation and Storage
Store at -80 degree C for 12 months (Avoid repeated freezing and thawing)
Shipping: Blue Ice
Chromosome Location
Chromosome: 16; NC_000016.9 (3064713..3068188, complement). Location: 16p13.3
3D Structure
ModBase 3D Structure for P56747
Species
Human
Tag
C-Mouse Fc tag
Reconstitution
Reconstitute with deionized water
Applications Tested/Suitable for CLDN6 recombinant protein
Western Blot (WB)

SDS-Page of CLDN6 recombinant protein

Figure 1. Human CLDN6 Protein, mFc Tag on SDS-PAGE under reducing condition.
Human CLDN6 Recombinant Protein – Cat# MBS188108

Other Notes

Small volumes of CLDN6 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CLDN6. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
claudin-6
NCBI Official Synonym Full Names
claudin 6
NCBI Official Symbol
CLDN6
UniProt Protein Name
Claudin-6
UniProt Synonym Protein Names
Skullin
Protein Family
UniProt Gene Name
CLDN6
UniProt Entry Name
CLD6_HUMAN
NCBI Protein Information
claudin-6; skullin

NCBI Summary for CLDN6

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.[provided by RefSeq, Aug 2010]
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UniProt Comments for CLDN6

Claudin-6: Plays a major role in tight junction-specific obliteration of the intercellular space. Belongs to the claudin family.

Protein type: Cell adhesion; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: tight junction; plasma membrane; integral to membrane

Molecular Function: identical protein binding; structural molecule activity

Biological Process: intercellular junction assembly and maintenance; viral reproduction; calcium-independent cell-cell adhesion
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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