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TIGIT Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS188137

This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high… More details

$290 / 0.01 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TIGIT, Recombinant Protein
Full Product Name
Recombinant human TIGIT Protein with C-human Fc tag
Product Gene Name
Product Synonym Names
Human TIGIT Protein, hFc Tag; TIGIT;VSIG9;VSTM3
Sequence
TIGIT(Met2 2-Pro141)+ hFc(Glu99- Ala330)
Host
HEK293 cells
Form/Format
Lyophilized from sterile PBS, pH 7.4. Normally 5%-78% trehalose is added as protectants before lyophilization.
Purity/Purification
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Preparation and Storage
Store at -80 degree C for 12 months (Avoid repeated freezing and thawing)
Shipping: Blue Ice
Molecular Weight
18,432 Da
OMIM
AK097192 mRNA
3D Structure
ModBase 3D Structure for Q495A1
Source
Human
Conjugation
C-Human Fc tag
Reconstitution
Reconstitute with deionized water
Applications Tested/Suitable for TIGIT recombinant protein
Western Blot (WB), ELISA (EIA)

ELISA (EIA) of TIGIT recombinant protein

Figure 1. Human TIGIT Protein, hFc Tag on SDS-PAGE under reducing condition.
TIGIT Recombinant Protein – Cat# MBS188137

ELISA (EIA) of TIGIT recombinant protein

Figure 1. Human TIGIT Protein, hFc Tag on SDS-PAGE under reducing condition.
TIGIT Recombinant Protein, ELISA (EIA) – Cat# MBS188137

SDS-Page of TIGIT recombinant protein

Figure 1. Human TIGIT Protein, hFc Tag on SDS-PAGE under reducing condition.
TIGIT Recombinant Protein, SDS-Page – Cat# MBS188137

Other Notes

Small volumes of TIGIT recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TIGIT purchase

MBS188137 is a recombinant protein targeting TIGIT. Also known as Recombinant human TIGIT Protein with C-human Fc tag. Host: HEK293 cells.

Additional Details

NCBI/Uniprot data below describe general gene information for TIGIT. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
T-cell immunoreceptor with Ig and ITIM domains
NCBI Official Synonym Full Names
T cell immunoreceptor with Ig and ITIM domains
NCBI Official Symbol
TIGIT
NCBI Official Synonym Symbols
VSIG9; VSTM3; WUCAM
UniProt Protein Name
T-cell immunoreceptor with Ig and ITIM domains
UniProt Synonym Protein Names
V-set and immunoglobulin domain-containing protein 9; V-set and transmembrane domain-containing protein 3
UniProt Gene Name
TIGIT
UniProt Synonym Gene Names
VSIG9; VSTM3
NCBI Protein Information
T-cell immunoreceptor with Ig and ITIM domains

UniProt Comments for TIGIT

Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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