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IL17RA Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS188148

Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A… More details

$290 / 0.01 mg +1 FREE 8GB USB
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
IL17RA, Recombinant Protein
Full Product Name
Recombinant human IL17RA protein with C-terminal 6xHis tag
Product Synonym Names
Human IL17RA Protein, His Tag; CD217;CDw217;IL-17RA;IL17R;CANDF5;hIL-17R
Sequence
IL17RA(Leu 33-Trp320)
Host
HEK293 cells
Form/Format
Lyophilized from sterile PBS, pH 7.4. Normally 5%-88% trehalose is added as protectants before lyophilization.
Purity/Purification
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Preparation and Storage
Store at -80 degree C for 12 months (Avoid repeated freezing and thawing)
Shipping: Blue Ice
Molecular Weight
96,122 Da
Chromosome Location
Chromosome: 22; NC_000022.10 (17565851..17596584). Location: 22q11.1
OMIM
605461
3D Structure
ModBase 3D Structure for Q96F46
Source
Human
Conjugation
C- 6xHis tag
Reconstitution
Reconstitute with deionized water
Applications Tested/Suitable for IL17RA recombinant protein
Western Blot (WB)

ELISA (EIA) of IL17RA recombinant protein

Figure 1. Human IL17RA Protein, His Tag on SDS-PAGE under reducing condition.
IL17RA Recombinant Protein – Cat# MBS188148

SDS-Page of IL17RA recombinant protein

Figure 1. Human IL17RA Protein, His Tag on SDS-PAGE under reducing condition.
IL17RA Recombinant Protein, SDS-Page – Cat# MBS188148

Other Notes

Small volumes of IL17RA recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL17RA purchase

MBS188148 is a recombinant protein targeting IL17RA. Also known as Recombinant human IL17RA protein with C-terminal 6xHis tag. Host: HEK293 cells.

Additional Details

NCBI/Uniprot data below describe general gene information for IL17RA. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
interleukin-17 receptor A
NCBI Official Synonym Full Names
interleukin 17 receptor A
NCBI Official Symbol
IL17RA
NCBI Official Synonym Symbols
CD217; IL17R; CANDF5; CDw217; IL-17RA; hIL-17R
UniProt Protein Name
Interleukin-17 receptor A
UniProt Synonym Protein Names
CDw217
UniProt Gene Name
IL17RA
UniProt Synonym Gene Names
IL17R; IL-17 receptor A; IL-17RA
UniProt Entry Name
I17RA_HUMAN
NCBI Protein Information
interleukin-17 receptor A; IL-17 receptor A

NCBI Summary for IL17RA

Interleukin 17A (IL17A)is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. [provided by RefSeq, Jul 2008]
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UniProt Comments for IL17RA

IL17RA: Receptor for IL17A and IL17F. Binds its IL17A ligand with low affinity, suggesting that additional components are involved in IL17A-induced signaling. Widely expressed.

Protein type: Receptor, cytokine; Membrane protein, integral

Chromosomal Location of Human Ortholog: 22q11.1

Cellular Component: integral to plasma membrane; extracellular region

Molecular Function: protein binding; interleukin-17 receptor activity

Biological Process: cell surface receptor linked signal transduction; positive regulation of interleukin-23 production; cytokine and chemokine mediated signaling pathway

Disease: Candidiasis, Familial, 5
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with IL17RA recombinant protein

 Reference Product  PubMed Publications
 IL17A recombinant protein  >87 publications with IL17RA and IL17A
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