Neisseria Gonorrhoeae Antibody – Mouse Monoclonal

Neisseria gonorrhoeae is a gram-negative coccus and is the cause of the sexually transmitted disease gonorrhea with humans as its only natural host. Although it does not produce any exotoxins, Neisseria gonorrhoeae has a wide range of virulence determinants. The first stages of infection, which include adherence and invasion, are mediated by surface components; N. gonorrhoeae first attaches to epithelial cells by means of its fimbriae. After initial attachment, the bacteria enter a second stage of binding mediated by the outer membrane protein P.II (also known as Opa) which is needed for tight binding and invasion of epithelial cells. P.II from one bacterium will bind to lipooligosaccharide of an adjacent bacterium, which allows for the construction of a small colony that may function similarly to a biofilm. Neisseria gonorrhoeae also produces an IgA1 protease that may take part in the colonization stage.

Small volumes of anti-Neisseria gonorrhoeae antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS190351 is an antibody targeting Neisseria gonorrhoeae. Also known as Neisseria gonorrhoeae Monoclonal Antibody. Host: Mouse.